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Work of Respiration In Bronchiolitis

Work of Respiration In Bronchiolitis Abstract Bronchiolitis in infancy is characterized by the rapid development of respiratory distress caused by obstructive lesions at the bronchiolar level which lead to acute pulmonary over-distention. When severe respiratory distress continues unabated by therapy, these infants appear to become exhausted. Exhaustion has been implicated as a factor contributing to the demise of such infants. It is important to determine to what extent this is true. The role of mechanical devices capable of aiding respiration has remained uncertain partly because this rather complex question has not been answered as yet. As part of a study on the mechanics of respiration in bronchiolitis, we have calculated the work of respiration in this disease and compared it with that performed by a group of infants with bronchopneumonia. Bronchopneumonia was selected because respiratory distress occurs without the apparent development of exhaustion. The purpose of this study was to ascertain whether the actual work performed References 1. Krieger, I.: Studies on Mechanics of Respiration in Infancy , Amer J Dis Child 105:439, 1963. 2. Cook, C. D., et al: Studies of Respiratory Physiology in Newborn Infant: III. Measurements of Mechanics of Respiration , J Clin Invest 36:440, 1957.Crossref 3. Otis, A. B.; Fenn, W. O.; and Rahn, H.: Mechanics of Breathing in Man , J Appl Physiol 2:592, 1950. 4. Krieger, I.: Mechanics of Respiration in Bronchiolitis , Pediatrics 33:45, 1964. 5. Otis, A. B., et al: Mechanical Factors in Distribution of Pulmonary Ventilation , J Appl Physiol 8:427, 1956. 6. Rossier, P. H.; Buhlmann, A. A.; and Wiesinger, K.: Respiration , Physiologic Principles and Their Clinical Applications, St. Louis: C. V. Mosby Co., 1960. 7. Helliesen, P. J., et al: Studies of Respiratory Physiology in Children , Pediatrics 22:80, 1958. 8. Cook, C. D., et al: Studies of Respiratory Physiology in Children: II. Lung Volumes and Mechanics of Respiration in Sixty-Four Patients With Cystic Fibrosis of the Pancreas , Pediatrics 24:181, 1959. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

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References (9)

Publisher
American Medical Association
Copyright
Copyright © 1964 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1964.02080060388010
Publisher site
See Article on Publisher Site

Abstract

Abstract Bronchiolitis in infancy is characterized by the rapid development of respiratory distress caused by obstructive lesions at the bronchiolar level which lead to acute pulmonary over-distention. When severe respiratory distress continues unabated by therapy, these infants appear to become exhausted. Exhaustion has been implicated as a factor contributing to the demise of such infants. It is important to determine to what extent this is true. The role of mechanical devices capable of aiding respiration has remained uncertain partly because this rather complex question has not been answered as yet. As part of a study on the mechanics of respiration in bronchiolitis, we have calculated the work of respiration in this disease and compared it with that performed by a group of infants with bronchopneumonia. Bronchopneumonia was selected because respiratory distress occurs without the apparent development of exhaustion. The purpose of this study was to ascertain whether the actual work performed References 1. Krieger, I.: Studies on Mechanics of Respiration in Infancy , Amer J Dis Child 105:439, 1963. 2. Cook, C. D., et al: Studies of Respiratory Physiology in Newborn Infant: III. Measurements of Mechanics of Respiration , J Clin Invest 36:440, 1957.Crossref 3. Otis, A. B.; Fenn, W. O.; and Rahn, H.: Mechanics of Breathing in Man , J Appl Physiol 2:592, 1950. 4. Krieger, I.: Mechanics of Respiration in Bronchiolitis , Pediatrics 33:45, 1964. 5. Otis, A. B., et al: Mechanical Factors in Distribution of Pulmonary Ventilation , J Appl Physiol 8:427, 1956. 6. Rossier, P. H.; Buhlmann, A. A.; and Wiesinger, K.: Respiration , Physiologic Principles and Their Clinical Applications, St. Louis: C. V. Mosby Co., 1960. 7. Helliesen, P. J., et al: Studies of Respiratory Physiology in Children , Pediatrics 22:80, 1958. 8. Cook, C. D., et al: Studies of Respiratory Physiology in Children: II. Lung Volumes and Mechanics of Respiration in Sixty-Four Patients With Cystic Fibrosis of the Pancreas , Pediatrics 24:181, 1959.

Journal

American Journal of Diseases of ChildrenAmerican Medical Association

Published: Apr 1, 1964

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