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(1993)
Protecting human research subjects : institutional review board guidebook
A. McCarthy, L. Richman, R. Hoffman, L. Rubenstein (2001)
Psychological screening of children for participation in nontherapeutic invasive research.Archives of pediatrics & adolescent medicine, 155 11
EDITORIAL FEW YEARS AGO, we rented the videotape Research involving children is always morally prob- of Roald Dahl’s book The Witches. My kids lematic. Such research is important to understand chil- generally like Dahl, especially Charlie and dren’s unique physiologic and pathologic characteris- the Chocolate Factory, and we thought that tics. This knowledge allows better medical treatment of A The Witches might be a fun movie. It was pediatric problems. However, children often cannot fully a big mistake. The movie starts out in the home of a happy, understand the risks and benefits of research, so they can- loving family. It evokes Disneylike comfort and charm. not give fully informed consent. Instead, children are The attentive parents are going out to dinner, and their asked to give their assent to participation, and parents son is staying with his grandmother. He is scared be- are asked for their permission to allow their children to cause his parents are leaving. They assure him that they participate. In the United States and Canada, a wide- will be home soon and kiss him good night. Then things spread consensus seems to have developed around the start to go bad. issue of pediatric research
JAMA Pediatrics – American Medical Association
Published: Nov 1, 2001
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