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When Should Renal Allografts be Removed?

When Should Renal Allografts be Removed? Abstract Most patients who receive a cadaver renal transplant have not been offered a kidney from a related, potential donor and are, for a variety of reasons, unsuitable candidates for chronic hemodialysis. The paucity of suitable donors limits the number of transplants that can be performed, and requires some recipients to wait as long as two years before a suitable donor becomes available. Furthermore, to decrease the risk of failure, it has become customary to perform transplants only when no circulating cytotoxic antibodies against the prospective donor exist in the recipient,1 and when the histocompatibility locus A (HL-A) match between donor and recipient is C or better, using the nomenclature of Terasaki.1,2 Despite these precautions complications have developed in the transplant or in the recipient. Under such circumstances removal of the transplant in anticipation of a second or third transplant at a later date must be considered. If there References 1. Terasaki, P.I.; Vredevoe, D.L.; and Mickey, M.R.: Serotyping for Homotransplantation. X. Survival of 196 Grafted Kidneys Subsequent to Typing , Transplantation 5( (suppl) ):1057-1070 (July) 1967.Crossref 2. Dossetor, J.B., et al: Cadaver Renal Transplants: Immunological Aspects, Proceedings of the Sixth International Congress on Allergology, ICS 144, Excerpta Medica, to be published. 3. MacKinnon, K.J., et al: Cadaver Renal Transplantation: Emphasis on Urological Aspects , J Urol 99:486-490 ( (May) ) 1968. 4. Dossetor, J.B., et al: Cadaver Kidney Transplant , Transplantation 5:844-853 ( (July) ) 1967.Crossref 5. Pitzele, S., et al: Method and Apparatus for Functional Evaluation of Isolated Hearts , Surgery 64:308-314 ( (July) ) 1968. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

When Should Renal Allografts be Removed?

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References (5)

Publisher
American Medical Association
Copyright
Copyright © 1969 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1969.01340140141021
Publisher site
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Abstract

Abstract Most patients who receive a cadaver renal transplant have not been offered a kidney from a related, potential donor and are, for a variety of reasons, unsuitable candidates for chronic hemodialysis. The paucity of suitable donors limits the number of transplants that can be performed, and requires some recipients to wait as long as two years before a suitable donor becomes available. Furthermore, to decrease the risk of failure, it has become customary to perform transplants only when no circulating cytotoxic antibodies against the prospective donor exist in the recipient,1 and when the histocompatibility locus A (HL-A) match between donor and recipient is C or better, using the nomenclature of Terasaki.1,2 Despite these precautions complications have developed in the transplant or in the recipient. Under such circumstances removal of the transplant in anticipation of a second or third transplant at a later date must be considered. If there References 1. Terasaki, P.I.; Vredevoe, D.L.; and Mickey, M.R.: Serotyping for Homotransplantation. X. Survival of 196 Grafted Kidneys Subsequent to Typing , Transplantation 5( (suppl) ):1057-1070 (July) 1967.Crossref 2. Dossetor, J.B., et al: Cadaver Renal Transplants: Immunological Aspects, Proceedings of the Sixth International Congress on Allergology, ICS 144, Excerpta Medica, to be published. 3. MacKinnon, K.J., et al: Cadaver Renal Transplantation: Emphasis on Urological Aspects , J Urol 99:486-490 ( (May) ) 1968. 4. Dossetor, J.B., et al: Cadaver Kidney Transplant , Transplantation 5:844-853 ( (July) ) 1967.Crossref 5. Pitzele, S., et al: Method and Apparatus for Functional Evaluation of Isolated Hearts , Surgery 64:308-314 ( (July) ) 1968.

Journal

Archives of Surgery – American Medical Association

Published: Aug 1, 1969

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