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When Should Clinicians Act on Non–Statistically Significant Results From Clinical Trials?

When Should Clinicians Act on Non–Statistically Significant Results From Clinical Trials? This Viewpoint discusses considerations that might lead physicians to change their practice based on RCTs reporting non–statistically significant differences in primary outcomes, including trial methodology, totality of evidence, cost, invasiveness, and labor-intensiveness of the interventions being compared. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

When Should Clinicians Act on Non–Statistically Significant Results From Clinical Trials?

JAMA , Volume 323 (22) – Jun 9, 2020

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Publisher
American Medical Association
Copyright
Copyright 2020 American Medical Association. All Rights Reserved.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2020.3508
Publisher site
See Article on Publisher Site

Abstract

This Viewpoint discusses considerations that might lead physicians to change their practice based on RCTs reporting non–statistically significant differences in primary outcomes, including trial methodology, totality of evidence, cost, invasiveness, and labor-intensiveness of the interventions being compared.

Journal

JAMAAmerican Medical Association

Published: Jun 9, 2020

References