Abstract • Papillary cystadenolymphoma, or Warthin's tumor, is a monomorphic adenoma found in salivary glands. It nearly always occurs in the parotid gland, and is reported to occur in 5% to 14% of all parotid tumors according to most studies. The tumor has a universally accepted male predominance, with an increasing incidence in females having been reported over the last four decades. A review of all primary parotid gland tumors seen at York (Pa) Hospital for the last 10 years was performed. Warthin's tumor was diagnosed histologically in 42 (30%) of 138 primary parotid gland tumors, with no significant sex predominance identified (22 men, 20 women). A significantly higher percentage of all parotid gland tumors, and especially Warthin's tumor, was associated with smoking in both males and females. (Arch Otolaryngol Head Neck Surg. 1992;118:477-478) References 1. Hildebrand O. Uber Angeborene Epitheliale Cysten und Fisteln des Halses . Arch Klin Chir . 1895;49:167-206. 2. Warthin AS. Papillary cystadenoma lymphomatosum: a rare teratoid of the parotid region . J Cancer Res . 1929;13:116-125. 3. Chapnik JS. The controversy of Warthin's tumor . Laryngoscope . 1983;93:695-716.Crossref 4. Attie JN, Sciubba JJ. Tumors of major and minor salivary glands: clinical and pathologic features . Curr Probl Surg . 1981;18:65-155.Crossref 5. Illes RW, Brian MB. A review of the tumors of the salivary gland . Surg Gynecol Obstet . 1986;163:399-404. 6. Eveson JW, Cawson RA. Warthin's tumor (cystadenolymphoma) of the salivary glands: a clinicopathological investigation of 278 cases . Oral Surg . 1986;61:256-262.Crossref 7. Lamelas J, Terry JH Jr, Alphonso AE. Warthin's tumor: multicentricity and increasing incidence in women . Am J Surg . 1987;154:347-351.Crossref 8. Ebbs SR, Webb AJ. Adenolymphoma of the parotid: aetiology, diagnosis and treatment . Br J Surg . 1986;73:627-630.Crossref 9. Kennedy TL. Warthin's tumor: a review indicating no male predominance . Laryngoscope . 1983;93:889-891.Crossref 10. Dietert SE. Papillary cystadenoma lymphomatosum (Warthin's tumor) in patients in a general hospital over a 24-year period . Am J Clin Pathol . 1975;63:866-875. 11. Wackym PA, Gray GF Jr, Rosenfeld L, Friedman I. Papillary cystic oncocytoma and Warthin's tumor of the parotid gland . J Laryngol Otol . 1988;100:679-686.Crossref 12. Allegra SR. Warthin's tumor: a hypersensitivity disease? Hum Pathol . 1971;2:403-420.Crossref 13. Marcus AC, Shopland DR, Crane LA, Lynn WR. Prevalence of cigarette smoking in the United States: estimates from the 1985 current population survey . J Natl Cancer Inst . 1989;81:409-414.Crossref 14. Sanders JR Jr, Hirata RM, Jaques DA. Salivary glands . Surg Clin North Am . 1986;66:59-81.
Archives of Otolaryngology - Head & Neck Surgery – American Medical Association
Published: May 1, 1992
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