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Vitamin D and Breast Cancer Survival—In Reply

Vitamin D and Breast Cancer Survival—In Reply Letters In Reply We appreciate the thoughtful comments of Grube and mor progression, poor prognosis, drug resistance, and shorter 1 2,3 Cardenas in response to our recent article. patient survival. Concordantly, positive expression of sur- We agree with the observation that many commercial in- vivin has been associated with a significantly higher risk of re- surance plans do cover the cost of secobarbital for use in aid- currence and decreased overall survival rates in patients with in-dying. Of the 35 patients at our center participating in the breast cancer. Although it is described as a biomarker predic- Death With Dignity program who were prescribed secobarbi- tive of aggressive cancer, survivin has been corroborated to be tal between 2010 and 2016, 12 patients (34%), all of whom had the key player of a mechanism by which myocytes at risk of commercial insurance, received some degree of coverage for apoptosis retain their viability. Survivin myocardial expres- this medication. Copayments for these 12 patients ranged from sion after acute myocardial infarction (AMI) has been related $2.00 to $1236.26. The remaining 23 patients (66%) either to the survival of at-risk myocardium and to a more favorable chose to pay cash for the medication http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Oncology American Medical Association

Vitamin D and Breast Cancer Survival—In Reply

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Publisher
American Medical Association
Copyright
Copyright 2017 American Medical Association. All Rights Reserved.
ISSN
2374-2437
eISSN
2374-2445
DOI
10.1001/jamaoncol.2017.1477
Publisher site
See Article on Publisher Site

Abstract

Letters In Reply We appreciate the thoughtful comments of Grube and mor progression, poor prognosis, drug resistance, and shorter 1 2,3 Cardenas in response to our recent article. patient survival. Concordantly, positive expression of sur- We agree with the observation that many commercial in- vivin has been associated with a significantly higher risk of re- surance plans do cover the cost of secobarbital for use in aid- currence and decreased overall survival rates in patients with in-dying. Of the 35 patients at our center participating in the breast cancer. Although it is described as a biomarker predic- Death With Dignity program who were prescribed secobarbi- tive of aggressive cancer, survivin has been corroborated to be tal between 2010 and 2016, 12 patients (34%), all of whom had the key player of a mechanism by which myocytes at risk of commercial insurance, received some degree of coverage for apoptosis retain their viability. Survivin myocardial expres- this medication. Copayments for these 12 patients ranged from sion after acute myocardial infarction (AMI) has been related $2.00 to $1236.26. The remaining 23 patients (66%) either to the survival of at-risk myocardium and to a more favorable chose to pay cash for the medication

Journal

JAMA Oncology – American Medical Association

Published: Aug 8, 2017

References

  • Association of serum level of vitamin D at diagnosis with breast cancer survival: a case-cohort analysis in the Pathways Study
    Yao, S; Kwan, ML; Ergas, IJ
  • Prognostic effects of 25-hydroxyvitamin D levels in early breast cancer
    Goodwin, PJ; Ennis, M; Pritchard, KI; Koo, J; Hood, N
  • Effect of vitamin D and calcium supplementation on cancer incidence in older women: a randomized clinical trial
    Lappe, J; Watson, P; Travers-Gustafson, D
  • Genetically low vitamin D concentrations and increased mortality: Mendelian randomisation analysis in three large cohorts
    Afzal, S; Brøndum-Jacobsen, P; Bojesen, SE; Nordestgaard, BG
  • Effect of monthly high-dose vitamin D supplementation on cardiovascular disease in the Vitamin D Assessment Study: a randomized clinical trial
    Scragg, R; Stewart, AW; Waayer, D