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Vision in Patients With Leber Congenital Amaurosis

Vision in Patients With Leber Congenital Amaurosis Abstract We read with interest the article by Fulton and coworkers1 in which the visual course of children with Leber congenital amaurosis was described. We applaud their efforts to measure the grating acuity of these preverbal children using Teller acuity cards, although we have some reservations about the correlation between grating acuities and optotype acuities.2-4 We reported a similar visual course in a cohort of 45 children that we observed longitudinally for a mean of 6.4 years.5 Six of these 45 patients had a documented deterioration of their visual acuity. The most severe visual deterioration occurred in a 15-year-old patient whose visual acuity had decreased from 20/120 to counting fingers at 3 ft OD and from 10/200 to hand movements OS during a 12-year period. All 6 of these patients, who were teenagers or young adults when reexamined, described this visual loss as slow and insidious. Three patients References 1. Fulton AB, Hansen RM, Mayer L. Vision in Leber congenital amaurosis . Arch Ophthalmol . 1996;114:698-703.Crossref 2. Kushner BJ. Grating acuity tests should not be used for social service purposes in preliterate children . Arch Ophthalmol . 1994;112:1030-1031.Crossref 3. Kushner BJ. Grating acuity tests should not be used for social service purposes in preliterate children . Arch Ophthalmol . 1995;113:971.Crossref 4. Kushner BJ, Lucchese NJ, Morton GV. Grating visual acuity with Teller cards compared with Snellen visual acuity in literate patients . Arch Ophthalmol . 1995;113:485-493.Crossref 5. Lambert SR, Kriss A, Taylor D, Coffey R, Pembrey M. Follow-up and diagnostic reappraisal of 75 patients with Leber's congenital amaurosis . Am J Ophthalmol . 1989;107:624-631. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Vision in Patients With Leber Congenital Amaurosis

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Publisher
American Medical Association
Copyright
Copyright © 1997 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1997.01100150295035
Publisher site
See Article on Publisher Site

Abstract

Abstract We read with interest the article by Fulton and coworkers1 in which the visual course of children with Leber congenital amaurosis was described. We applaud their efforts to measure the grating acuity of these preverbal children using Teller acuity cards, although we have some reservations about the correlation between grating acuities and optotype acuities.2-4 We reported a similar visual course in a cohort of 45 children that we observed longitudinally for a mean of 6.4 years.5 Six of these 45 patients had a documented deterioration of their visual acuity. The most severe visual deterioration occurred in a 15-year-old patient whose visual acuity had decreased from 20/120 to counting fingers at 3 ft OD and from 10/200 to hand movements OS during a 12-year period. All 6 of these patients, who were teenagers or young adults when reexamined, described this visual loss as slow and insidious. Three patients References 1. Fulton AB, Hansen RM, Mayer L. Vision in Leber congenital amaurosis . Arch Ophthalmol . 1996;114:698-703.Crossref 2. Kushner BJ. Grating acuity tests should not be used for social service purposes in preliterate children . Arch Ophthalmol . 1994;112:1030-1031.Crossref 3. Kushner BJ. Grating acuity tests should not be used for social service purposes in preliterate children . Arch Ophthalmol . 1995;113:971.Crossref 4. Kushner BJ, Lucchese NJ, Morton GV. Grating visual acuity with Teller cards compared with Snellen visual acuity in literate patients . Arch Ophthalmol . 1995;113:485-493.Crossref 5. Lambert SR, Kriss A, Taylor D, Coffey R, Pembrey M. Follow-up and diagnostic reappraisal of 75 patients with Leber's congenital amaurosis . Am J Ophthalmol . 1989;107:624-631.

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Feb 1, 1997

References

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