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References (10)
-
B. Blumberg, A. Sutnick, W. London (1968)
Hepatitis and leukemia: their relation to Australia antigen.Bulletin of the New York Academy of Medicine, 44 12
-
S. Krugman, J. Giles (1970)
Viral hepatitis. New light on an old disease.JAMA, 212 6
-
Sutnick AI Blumberg BS (1968)
Hepatitis and leukemia: Their relation to Australia antigenBull NY Acad Med, 44
-
G. Mirick, R. Shank (1959)
An epidemic of serum hepatits studied under controlled conditions.Transactions of the American Clinical and Climatological Association, 71
-
J. Giles, S. Krugman (1969)
Viral hepatitis. Immunoglobulin response during the course of the disease.JAMA, 208 3
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R. Mccollum (1969)
Viral HepatitisThe Yale Journal of Biology and Medicine, 52
-
McCollum RW Giles JP (1969)
Relationship of Australia/SH antigen to the Willowbrook MS-2 strainNew Eng J Med, 281
-
S. Krugman, J. Giles, J. Hammond (1967)
Infectious hepatitis. Evidence for two distinctive clinical, epidemiological, and immunological types of infection.JAMA, 200 5
-
Prince AM (1968)
An antigen detected in the blood during the incubation period of serum hepatitisProc Nat Acad Sci USA, 60
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A. Prince (1968)
An antigen detected in the blood during the incubation period of serum hepatitis.Proceedings of the National Academy of Sciences of the United States of America, 60 3
- Publisher
- American Medical Association
- Copyright
- Copyright © 1972 American Medical Association. All Rights Reserved.
- ISSN
- 0002-922X
- DOI
- 10.1001/archpedi.1972.02110100013005
- Publisher site
- See Article on Publisher Site
Abstract
Abstract Knowledge of the clinical, epidemiological, and laboratory aspects of viral hepatitis is essential for the differential diagnosis of infections caused by A (IH) and B (SH) viruses. Studies of the natural history of the disease and observations of patients during the course of epidemics have provided valuable clues for the differentiation of infectious hepatitis from serum hepatitis. Clinical Aspects The incubation period of viral hepatitis, type A ranges between 15 to 50 days with an average of about 30 days regardless of the route of infection; it is essentially the same following an oral or parenteral exposure.1 In contrast, the incubation period of viral hepatitis, type B is much longer, ranging between 60 and 160 days, the average is 90 days. Although hepatitis B virus is usually transmitted by the parenteral route, it is well recognized that it can also be spread by contact and by the oral route. References 1. Krugman S, Giles JP: Viral hepatitis: New light on an old disease . JAMA 212:1019-1029, 1970.Crossref 2. Mirick GS, Shank RE: An epidemic of serum hepatitis studied under controlled conditions . Trans Amer Clin Climat Assoc 71:176-190, 1959. 3. Krugman S, Giles JP, Hammond J: Infectious hepatitis: Evidence for two distinctive clinical, epidemiological and immunological types of infection . JAMA 200:365-375, 1967.Crossref 4. Blumberg BS, Sutnick AI, London WT: Hepatitis and leukemia: Their relation to Australia antigen . Bull NY Acad Med 44:1566-1586, 1968. 5. Giles JP, Krugman S: Viral hepatitis: Immunoglobulin response during the course of the disease . JAMA 208:497-503, 1969.Crossref 6. Prince AM: An antigen detected in the blood during the incubation period of serum hepatitis . Proc Nat Acad Sci USA 60:814-821, 1968.Crossref 7. Giles JP, McCollum RW, Berndtson LW Jr, et al: Relationship of Australia/SH antigen to the Willowbrook MS-2 strain . New Eng J Med 281:119-122, 1969.Crossref
Journal
American Journal of Diseases of Children – American Medical Association
Published: Apr 1, 1972