Abstract In considering the toxicity of chloroform it is necessary to recall that a number of chemical processes are involved in its manufacture and that, in the various processes, a considerable number of chemical substances interact to give chloroform as one of the main products. Other products are formed, however, or remain from the mother substances which are used in the manufacturing process. The chloroform itself, of course, does not differ whether it be derived from acetone,1 alcohol, methane, carbon tetrachlorid1 or chloral, but there exist on the market many grades of chloroform, more or less contaminated with by-products of manufacture, in addition to the very best anesthetic grades freed from these products by purification, all of which are known under the general term "chloroform." Even chloroform of the anesthetic grade, however, is not pure CHCl3 but contains in addition a small amount of References 1. The most important sources of chloroform. 2. Baskerville and Hamor : Jour. Indust. and Engin. Chem. , 1912, iv, 212.Crossref 3. Fiegel and Meier : Biochem. Ztschr. , 1906, i, 316. 4. Schafer and Scharlieb : Jour. Physiol. Proc. , 1903, xxix, 17. 5. Embley and Martin: Jour. Physiol. , 1905, xxxii, 147. 6. Waller: Nature , 1907, lxxvi, 402. 7. Tunnicliffe: Pharm. Jour. , xviii, 315. 8. Lehmann: Arch. f. Hyg. , 1903, xlvi, 322. 9. Lee: Liverpool Med. Chir. Jour. , 1895, xv, 412. 10. Buxton: Brit. Med. Jour. , 1912, i, 582.Crossref 11. Squibb & Sons, Parke, Davis & Co., Mallinckrodt Chemical Works, and Albany Chemical Company. 12. It seems advisable to eliminate these figures in estimating the toxicity of a given chloroform as this is not nearly so important as the fact of death itself in measuring toxicity. These figures have been introduced into this and a later table merely to show the lack of relationship between them.
Archives of Internal Medicine – American Medical Association
Published: Jun 1, 1915
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera