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Variations in Recurrent Active Toxoplasmic Retinochoroiditis

Variations in Recurrent Active Toxoplasmic Retinochoroiditis Abstract Toxoplasmic retinochoroiditis in 63 referred patients first occurred between ages 7 and 57 with a mean age of 25 years. Each patient had an average of 2.7 episodes, with a range of 1 to 13. The episodes averaged 4.2 months, ranging from one week to two years. Three morphologic variations were seen: large destructive, punctate inner retinal, and punctate deep with subretinal fluid at the macula. These types had different prognoses for vision, episode duration, and complications. Recognition of variations is essential for design of therapeutic trials. References 1. van Metre, T.E.; Knox, D.L.; and Maumenee, A.E.: The Relations Between Toxoplasmosis and Focal Exudative Retinochoroiditis , Amer J Ophthal 58:8-21 ( (July) ) 1964. 2. Perkins, E.S.: Uveitis and Toxoplasmosis , Boston: Little, Brown and Company, 1961. 3. Perkins, E.S.; Smith, C.H.; and Schofield, P.B.: Treatment of Uveitis With Pyrimethamine (Daraprim) , Brit J Ophthal 40:577-586, 1956.Crossref 4. Acers, T.E.: Toxoplasma Retinochoroiditis: A Double Blind Study , Arch Ophthal 71:58-62 ( (Jan) ) 1964.Crossref 5. Ghosh, M.; Levy, P.M.; and Leopold, I.: Therapy of Toxoplasmosis , Amer J Ophthal 59:55-61 ( (Jan) ) 1965. 6. Hogan, M.J.; Kimura, S.; and O'Connor, G.R.: Ocular Toxoplasmosis , Arch Ophthal 72:592-600 ( (Nov) ) 1964.Crossref 7. Maumenee, A.E. (ed.): Uveitis, Symposium by the Council for Research Into Glaucoma and Allied Diseases , Survey Ophthal 4:271-423 ( (June) ) 1959. 8. Maumenee, A.E. (ed.): Toxoplasmosis, Symposium by the Council for Research Into Glaucoma and Allied Diseases , Survey Ophthal 6:699-972 ( (Dec 1) ) 1961. 9. O'Conner, G.R., and Remington, J.: Therapy of Toxoplasmic Retinochoroiditis, Letter to the Editor , Arch Ophthal 71:883-884 ( (June) ) 1964.Crossref 10. Desmonts, G.: Definitive Serological Diagnosis of Ocular Toxoplasmosis , Arch Ophthal 76:839-851 ( (Dec) ) 1966.Crossref 11. Braley, A.E.: in Maumenee, A.E.( ed.): Uveitis, Symposium by the Council for Research Into Glaucoma and Allied Diseases , Survey Ophthal 4:238 ( (June) ) 1959. 12. Hogan, M.J.: in Maumenee, A.E. (ed.): Toxoplasmosis, Symposium by the Council for Research Into Glaucoma and Allied Diseases , Survey Ophthal 6:848 ( (Dec 1) ) 1961. 13. Hogan, M.J.: in Maumenee, A.E. (ed.): Uveitis, Symposium by the Council for Research Into Glaucoma and Allied Diseases , Survey Ophthal 4:228 ( (June) ) 1959. 14. Hogan, M.J.: in Maumenee, A.E. (ed.): Uveitis, Symposium by the Council for Research Into Glaucoma and Allied Diseases , Survey Ophthal 4:244 ( (June) ) 1959. 15. Frenkel, J.: Pathogenesis of Toxoplasmosis With a Consideration of Cyst Rupture in Besnoitia Infection , Survey Ophthal 6:799-825, 1961. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Variations in Recurrent Active Toxoplasmic Retinochoroiditis

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Publisher
American Medical Association
Copyright
Copyright © 1969 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1969.00990010483005
Publisher site
See Article on Publisher Site

Abstract

Abstract Toxoplasmic retinochoroiditis in 63 referred patients first occurred between ages 7 and 57 with a mean age of 25 years. Each patient had an average of 2.7 episodes, with a range of 1 to 13. The episodes averaged 4.2 months, ranging from one week to two years. Three morphologic variations were seen: large destructive, punctate inner retinal, and punctate deep with subretinal fluid at the macula. These types had different prognoses for vision, episode duration, and complications. Recognition of variations is essential for design of therapeutic trials. References 1. van Metre, T.E.; Knox, D.L.; and Maumenee, A.E.: The Relations Between Toxoplasmosis and Focal Exudative Retinochoroiditis , Amer J Ophthal 58:8-21 ( (July) ) 1964. 2. Perkins, E.S.: Uveitis and Toxoplasmosis , Boston: Little, Brown and Company, 1961. 3. Perkins, E.S.; Smith, C.H.; and Schofield, P.B.: Treatment of Uveitis With Pyrimethamine (Daraprim) , Brit J Ophthal 40:577-586, 1956.Crossref 4. Acers, T.E.: Toxoplasma Retinochoroiditis: A Double Blind Study , Arch Ophthal 71:58-62 ( (Jan) ) 1964.Crossref 5. Ghosh, M.; Levy, P.M.; and Leopold, I.: Therapy of Toxoplasmosis , Amer J Ophthal 59:55-61 ( (Jan) ) 1965. 6. Hogan, M.J.; Kimura, S.; and O'Connor, G.R.: Ocular Toxoplasmosis , Arch Ophthal 72:592-600 ( (Nov) ) 1964.Crossref 7. Maumenee, A.E. (ed.): Uveitis, Symposium by the Council for Research Into Glaucoma and Allied Diseases , Survey Ophthal 4:271-423 ( (June) ) 1959. 8. Maumenee, A.E. (ed.): Toxoplasmosis, Symposium by the Council for Research Into Glaucoma and Allied Diseases , Survey Ophthal 6:699-972 ( (Dec 1) ) 1961. 9. O'Conner, G.R., and Remington, J.: Therapy of Toxoplasmic Retinochoroiditis, Letter to the Editor , Arch Ophthal 71:883-884 ( (June) ) 1964.Crossref 10. Desmonts, G.: Definitive Serological Diagnosis of Ocular Toxoplasmosis , Arch Ophthal 76:839-851 ( (Dec) ) 1966.Crossref 11. Braley, A.E.: in Maumenee, A.E.( ed.): Uveitis, Symposium by the Council for Research Into Glaucoma and Allied Diseases , Survey Ophthal 4:238 ( (June) ) 1959. 12. Hogan, M.J.: in Maumenee, A.E. (ed.): Toxoplasmosis, Symposium by the Council for Research Into Glaucoma and Allied Diseases , Survey Ophthal 6:848 ( (Dec 1) ) 1961. 13. Hogan, M.J.: in Maumenee, A.E. (ed.): Uveitis, Symposium by the Council for Research Into Glaucoma and Allied Diseases , Survey Ophthal 4:228 ( (June) ) 1959. 14. Hogan, M.J.: in Maumenee, A.E. (ed.): Uveitis, Symposium by the Council for Research Into Glaucoma and Allied Diseases , Survey Ophthal 4:244 ( (June) ) 1959. 15. Frenkel, J.: Pathogenesis of Toxoplasmosis With a Consideration of Cyst Rupture in Besnoitia Infection , Survey Ophthal 6:799-825, 1961.

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Apr 1, 1969

References