Abstract We report the clinical, hematologic, and survival characteristics of 12 patients with lymphosarcoma primarily involving the marrow but without substantial nodal disease. The importance of the biopsy in establishing this diagnosis is stressed, since in 7 of the 12 cases the diagnosis would not have been made had only a marrow aspiration been performed. (Arch Intern Med 137:52-54, 1977) References 1. Han T, Stutzman L, Roque A: Bone marrow biopsy in Hodgkin's disease and other neoplastic disease . JAMA 217:1239-1251, 1971.Crossref 2. Gram V, Pool JL, Mayer K: Comparative study of bone marrow aspiration and biopsy in patients with neoplastic disease . Cancer 19:1898-1900, 1966.Crossref 3. Webb DI, Ubogy G, Silver RT: Importance of bone marrow biopsy in the clinical staging of Hodgkin's disease . Cancer 26:313-317, 1970.Crossref 4. Vinciguerra V, Silver RT: The importance of bone marrow biopsy in the staging of patients with lymphosarcoma . Blood 41:913-920, 1973. 5. Silver RT: Morphology of the Blood and Marrow in Clinical Practice . New York, Grune & Stratton, 1970. 6. Rappaport H, Winter WJ, Hicks EB: Follicular lymphoma: A reevaluation of its position in the scheme of malignant lymphoma, based on a survey of 253 cases . Cancer 9:792-821, 1956.Crossref 7. Kozinger B, Ellman L, Aisenberg A: Lymphoma present as bone marrow failure . Cancer 35:1426-1429, 1975.Crossref 8. Zacharski L, Linman J: Chronic lymphocytic leukemia versus chronic lymphosarcoma cell leukemia . Am J Med 47:76-81, 1969.Crossref 9. McFarland W, Dameshek W: Biopsy of the bone marrow with the Vim-Silverman needle . JAMA 166:1464-1466, 1958.Crossref 10. Rosenberg SA, Diamond HD, Jaslowitz B, et al: Lymphosarcoma: A review of 1,269 cases . Medicine 40:31, 1961.Crossref 11. Gall EA, Mallory RB: Malignant lymphoma . Am J Pathol 18:381, 1942. 12. Sugarbaker ED, Craver LF: Lymphosarcoma . JAMA 115:17, 1940. 13. Wethererly-Meir G, Smith P, Grake MR, et al: Follicular lymphoma . Quart J Med 21:327, 1952. 14. Galton DAG, Goldman JM, Wiltshaw E, et al: Prolymphocytic leukemia . Br J Haematol 27:7, 1974.Crossref 15. Peters MV, Masselback MD, Brown TS: The natural history of the lymphomas related to clinical classification , in Chris JD, Zarafonetes MD (eds): Proceedings of the International Conference of Leukemia and Lymphoma . Philadelphia, Lea & Febiger Publishers, 1968. 16. Ultman JE, Nixon DD: The therapy of lymphoma . Semin Hematol 6:376, 1969.
Archives of Internal Medicine – American Medical Association
Published: Jan 1, 1977