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Validation of the Association Between Neurologic Improvement With Decline in Blood Pressure and Recanalization in Stroke—Reply

Validation of the Association Between Neurologic Improvement With Decline in Blood Pressure and... Letters Corresponding Author: Martin Ebinger, MD, Department of Neurology, Center 0.534-4.927; P = .28). The median NIHSS score of 20 points in for Stroke Research Berlin, Charité–Universitätsmedizin Berlin, Berlin 10117, our cohort is high enough to address the authors’ concern of Germany (martin.ebinger@charite.de). a poor relationship between low NIHSS score and drop in Conflict of Interest Disclosures: Dr Audebert has received speaker honoraria blood pressure with recanalization. In a separate cohort of from Boehringer Ingelheim, the manufacturer of alteplase (not involved in this 66 patients with internal carotid artery occlusion, there was trial), and speaker and consultancy honoraria from Lundbeck A/S, which has conducted an acute stroke thrombolysis trial. No other disclosures were similarly no significant association between a drop in blood reported. pressure of 20 mm Hg or greater with a reduction of NIHSS Funding/Support: The Prehospital Acute Neurological Treatment and score of 4 or more points and recanalization (odds ratio, Optimization of Medical Care in Stroke Study was supported by Zukunftsfonds 2.500; 95% CI, 0.530-11.785; P = .21). Berlin and the Technology Foundation Berlin, with cofinancing by the European We previously described a significant relationship be- Regional Development Fund. tween arterial recanalization and neurological improvement Role of http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Neurology American Medical Association

Validation of the Association Between Neurologic Improvement With Decline in Blood Pressure and Recanalization in Stroke—Reply

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Publisher
American Medical Association
Copyright
Copyright 2015 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6149
eISSN
2168-6157
DOI
10.1001/jamaneurol.2014.4690
pmid
25867726
Publisher site
See Article on Publisher Site

Abstract

Letters Corresponding Author: Martin Ebinger, MD, Department of Neurology, Center 0.534-4.927; P = .28). The median NIHSS score of 20 points in for Stroke Research Berlin, Charité–Universitätsmedizin Berlin, Berlin 10117, our cohort is high enough to address the authors’ concern of Germany (martin.ebinger@charite.de). a poor relationship between low NIHSS score and drop in Conflict of Interest Disclosures: Dr Audebert has received speaker honoraria blood pressure with recanalization. In a separate cohort of from Boehringer Ingelheim, the manufacturer of alteplase (not involved in this 66 patients with internal carotid artery occlusion, there was trial), and speaker and consultancy honoraria from Lundbeck A/S, which has conducted an acute stroke thrombolysis trial. No other disclosures were similarly no significant association between a drop in blood reported. pressure of 20 mm Hg or greater with a reduction of NIHSS Funding/Support: The Prehospital Acute Neurological Treatment and score of 4 or more points and recanalization (odds ratio, Optimization of Medical Care in Stroke Study was supported by Zukunftsfonds 2.500; 95% CI, 0.530-11.785; P = .21). Berlin and the Technology Foundation Berlin, with cofinancing by the European We previously described a significant relationship be- Regional Development Fund. tween arterial recanalization and neurological improvement Role of

Journal

JAMA NeurologyAmerican Medical Association

Published: Apr 1, 2015

References