Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You and Your Team.

Learn More →

VACCINE-DERIVED POLIOMYELITIS

VACCINE-DERIVED POLIOMYELITIS Abstract To the Editor.—The case report, "Paralytic Poliomyelitis in an Unimmunized Child: Apparent Result of a Vaccine-Derived Poliovirus" by Cesario and others (Amer J Dis Child118:895, 1969) is a careful report of clinical and laboratory studies with factual material with which no one could disagree. A 5-year-old child developed clinical polio, was found to have type 2 in his stool, and antibodies rose against the strain. Quite acceptably the patient had type 2 poliomyelitis. Laboratory tests showed that the isolate, by way of Wecker and temperature markers, was a "vaccine-like" strain. His sister also harbored a fecal infection which was type 2 but showed marks of an "intermediate strain (which)... was possibly a vaccine derived strain." One may justifiably conclude that with intimate household exposure the virus isolates were identical even though they had different marker characteristics; it is unlikely that the type 2 viruses were simultaneously acquired References 1. Wilson G: The Hazards of Immunization . London, Athlone Press of the University of London, 1967. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

VACCINE-DERIVED POLIOMYELITIS

Abstract

Abstract To the Editor.—The case report, "Paralytic Poliomyelitis in an Unimmunized Child: Apparent Result of a Vaccine-Derived Poliovirus" by Cesario and others (Amer J Dis Child118:895, 1969) is a careful report of clinical and laboratory studies with factual material with which no one could disagree. A 5-year-old child developed clinical polio, was found to have type 2 in his stool, and antibodies rose against the strain. Quite acceptably the patient had type 2...
Loading next page...
 
/lp/american-medical-association/vaccine-derived-poliomyelitis-IVwKrbVc0z
Publisher
American Medical Association
Copyright
Copyright © 1970 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1970.02100050548017
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor.—The case report, "Paralytic Poliomyelitis in an Unimmunized Child: Apparent Result of a Vaccine-Derived Poliovirus" by Cesario and others (Amer J Dis Child118:895, 1969) is a careful report of clinical and laboratory studies with factual material with which no one could disagree. A 5-year-old child developed clinical polio, was found to have type 2 in his stool, and antibodies rose against the strain. Quite acceptably the patient had type 2 poliomyelitis. Laboratory tests showed that the isolate, by way of Wecker and temperature markers, was a "vaccine-like" strain. His sister also harbored a fecal infection which was type 2 but showed marks of an "intermediate strain (which)... was possibly a vaccine derived strain." One may justifiably conclude that with intimate household exposure the virus isolates were identical even though they had different marker characteristics; it is unlikely that the type 2 viruses were simultaneously acquired References 1. Wilson G: The Hazards of Immunization . London, Athlone Press of the University of London, 1967.

Journal

American Journal of Diseases of ChildrenAmerican Medical Association

Published: Jun 1, 1970

References