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Vaccination Status of Patients in an Outbreak of Acute Poliomyelitis

Vaccination Status of Patients in an Outbreak of Acute Poliomyelitis Abstract Considerable interest has been aroused in the degree of protection afforded by partial or complete poliomyelitis vaccination to persons who became infected with the virus of poliomyelitis. Related to this is the probability that commercially prepared poliomyelitis vaccine is of inconstant potency and therefore produces inconstant degrees of protection. A high incidence of acute poliomyelitis occurred in the middle Tennessee area during the summer of 1959 and made possible a study of the effects of vaccination with killed virus vaccine on the characteristics of the disease. An effort was made to relate vaccination status to the degree of paralysis. Patient Material Sixty-nine patients were seen during the acute phase of the disease and are included in this study. The clinical diagnosis was based on the characteristic historical, physical, and laboratory findings of acute poliomyelitis. For each patient, the diagnosis was confirmed by virus isolation and/or serological data. Patients who were References 1. Schmidt, N. J., and Lennette, E. H.: A Complement Fixation Test for Poliomyelitis , J. Exper. Med. 102:133, 1955.Crossref 2. Gonnella, C.; Harmon, G., and Jacobs, M.: Role of Physical Therapist in Gamma Globulin Poliomyelitis Prevention Study , Phys. Therapy Rev. 33:337, 1953. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

Vaccination Status of Patients in an Outbreak of Acute Poliomyelitis

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Publisher
American Medical Association
Copyright
Copyright © 1960 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1960.04020040859008
Publisher site
See Article on Publisher Site

Abstract

Abstract Considerable interest has been aroused in the degree of protection afforded by partial or complete poliomyelitis vaccination to persons who became infected with the virus of poliomyelitis. Related to this is the probability that commercially prepared poliomyelitis vaccine is of inconstant potency and therefore produces inconstant degrees of protection. A high incidence of acute poliomyelitis occurred in the middle Tennessee area during the summer of 1959 and made possible a study of the effects of vaccination with killed virus vaccine on the characteristics of the disease. An effort was made to relate vaccination status to the degree of paralysis. Patient Material Sixty-nine patients were seen during the acute phase of the disease and are included in this study. The clinical diagnosis was based on the characteristic historical, physical, and laboratory findings of acute poliomyelitis. For each patient, the diagnosis was confirmed by virus isolation and/or serological data. Patients who were References 1. Schmidt, N. J., and Lennette, E. H.: A Complement Fixation Test for Poliomyelitis , J. Exper. Med. 102:133, 1955.Crossref 2. Gonnella, C.; Harmon, G., and Jacobs, M.: Role of Physical Therapist in Gamma Globulin Poliomyelitis Prevention Study , Phys. Therapy Rev. 33:337, 1953.

Journal

American Journal of Diseases of ChildrenAmerican Medical Association

Published: Dec 1, 1960

References