Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You and Your Team.

Learn More →

Use of Electron-Beam Sterilized Hemodialysis Membranes and Risk of Thrombocytopenia

Use of Electron-Beam Sterilized Hemodialysis Membranes and Risk of Thrombocytopenia ORIGINAL CONTRIBUTION Use of Electron-Beam Sterilized Hemodialysis Membranes and Risk of Thrombocytopenia Mercedeh Kiaii, MD, FRCPC Context Thrombocytopenia is not widely recognized as a potential dialyzer-related complication. Following the observation of significant thrombocytopenia among 20 Ognjenka Djurdjev, MSc patients undergoing hemodialysis in a single dialysis unit after the introduction of dia- Myriam Farah, MD, FRCPC lyzers sterilized by electron beam (e-beam), a larger investigation was undertaken. Adeera Levin, MD, FRCPC Objective To determine the prevalence and etiology of thrombocytopenia in he- Beverly Jung, MD, FRCPC modialysis populations of 2 Canadian provinces (British Columbia and Alberta). Jennifer MacRae, MSc, MD, FRCPC Design, Setting, and Participants A cohort study of patients undergoing hemo- dialysis in British Columbia (n = 1706) and southern Alberta (n = 425) between April 1, DVERSE DEVICE REACTIONS TO 2009, and November 30, 2010. Retrospective analyses of historical patient, labora- hemodialysis treatments are tory, and dialyzer data predating conversion to e-beam dialyzers were undertaken, uncommon but can still oc- with prospective collection of predialysis and postdialysis platelet counts before and after the change from e-beam to non–e-beam sterilized dialyzers in September 2009. Acur in today’s era of hemodi- alysis membranes and technology. Dur- Main Outcome Measure Significant http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Use of Electron-Beam Sterilized Hemodialysis Membranes and Risk of Thrombocytopenia

Loading next page...
 
/lp/american-medical-association/use-of-electron-beam-sterilized-hemodialysis-membranes-and-risk-of-QdZ6sF0McJ
Publisher
American Medical Association
Copyright
Copyright 2011 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2011.1499
pmid
22009100
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL CONTRIBUTION Use of Electron-Beam Sterilized Hemodialysis Membranes and Risk of Thrombocytopenia Mercedeh Kiaii, MD, FRCPC Context Thrombocytopenia is not widely recognized as a potential dialyzer-related complication. Following the observation of significant thrombocytopenia among 20 Ognjenka Djurdjev, MSc patients undergoing hemodialysis in a single dialysis unit after the introduction of dia- Myriam Farah, MD, FRCPC lyzers sterilized by electron beam (e-beam), a larger investigation was undertaken. Adeera Levin, MD, FRCPC Objective To determine the prevalence and etiology of thrombocytopenia in he- Beverly Jung, MD, FRCPC modialysis populations of 2 Canadian provinces (British Columbia and Alberta). Jennifer MacRae, MSc, MD, FRCPC Design, Setting, and Participants A cohort study of patients undergoing hemo- dialysis in British Columbia (n = 1706) and southern Alberta (n = 425) between April 1, DVERSE DEVICE REACTIONS TO 2009, and November 30, 2010. Retrospective analyses of historical patient, labora- hemodialysis treatments are tory, and dialyzer data predating conversion to e-beam dialyzers were undertaken, uncommon but can still oc- with prospective collection of predialysis and postdialysis platelet counts before and after the change from e-beam to non–e-beam sterilized dialyzers in September 2009. Acur in today’s era of hemodi- alysis membranes and technology. Dur- Main Outcome Measure Significant

Journal

JAMAAmerican Medical Association

Published: Oct 19, 2011

References