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E. Boas (1929)
The ventricular rate in auricular fibrillation studies with the cardiotachometerAmerican Heart Journal, 4
H. Gold, N. Kwit, H. Otto, T. Fox (1939)
ON VAGAL AND EXTRAVAGAL FACTORS IN CARDIAC SLOWING BY DIGITALIS IN PATIENTS WITH AURICULAR FIBRILLATION.The Journal of clinical investigation, 18 4
H. Gold, N. Kwit, H. Otto, T. Fox (1939)
PHYSIOLOGICAL ADAPTATIONS IN CARDIAC SLOWING BY DIGITALIS AND THEIR BEARING ON PROBLEMS OF DIGITALIZATION IN PATIENTS WITH AURICULAR FIBRILLATIONJournal of Pharmacology and Experimental Therapeutics, 67
H. Gasser, W. Meek (1914)
A STUDY OF THE MECHANISMS BY WHICH MUSCULAR EXERCISE PRODUCES ACCELERATION OF THE HEARTAmerican Journal of Physiology, 34
E. Boas (1931)
Digitalis dosage in auricular fibrillationAmerican Heart Journal, 6
W. Weinstein, J. Plaut, L. Katz (1940)
LIMITATIONS OF THE USE OF DIGITALIS FOR AMBULATORY PATIENTS WITH AURICULAR FIBRILLATION.The American Journal of the Medical Sciences, 199
The ventricular rate serves as the chief guide to the degree of digitalization of patients with auricular fibrillation. The customary procedure is to give enough digitalis to reduce the rate of the ventricles to about 70 beats a minute and to maintain it at that level. It is well known, however, that if this result is attained with the patient at complete physical rest the rate in some cases mounts considerably when the patient is up and about. Furthermore, it may show wide fluctuations with moderate effort. Sir Thomas Lewis1 stated: "Although it is usually possible to control the rate in cases of auricular fibrillation, when the patients are at rest or quietly exercising, it is rarely possible to control the rates adequately in conditions of freer exercise." In a recent report by Weinstein, Plaut and Katz2 a contrary observation was made. In a previous study3 it
JAMA – American Medical Association
Published: May 17, 1941
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