EDITORIAL Use of Autologous Serum in the Treatment of Ocular Surface Disorders HE USE OF AUTOLOGOUS SERUM FOR TREAT- PERSISTENT EPITHELIAL DEFECTS ing ocular surface disorder has a long his- tory that dates back at least to the 1970s Several studies have described the successful use of au- when autologous serum was used via a mo- tologous serum in the treatment of persistent epithelial T bile ocular perfusion pump to treat ocu- defects recalcitrant to standard medical therapies. Dif- 1 2 lar alkali burns. Subsequently, a report in the rheuma- 3,4,7-10 ferent investigators have used concentrations of au- tologic literature appeared in 1984 discussing the use of tologous serum ranging from 20% to 100% in the treat- autologous serum as a tear substitute. Although prob- ment of persistent epithelial defects and have demonstrated ably used more often than it was publicized to be, the a healing rate of between 20% and 60% at 2 weeks and use of autologous serum for the treatment of ocular sur- between 47% and 83% at 4 weeks. Furthermore, it has face disorder did not appear to garner widespread inter- been suggested that the length of time required for heal- est until the late
JAMA Ophthalmology – American Medical Association
Published: Dec 1, 2011
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera