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S. Madsbad, O. Faber, C. Binder, P. Mcnair, C. Christiansen, I. Transbøl (1978)
Prevalence of Residual Beta-cell Function in Insulin-Dependent Diabetics in Relation to Age at Onset and Duration of DiabetesDiabetes, 27
M. Block, R. Rosenfield, M. Mako, D. Steiner, A. Rubenstein (1973)
Sequential changes in beta-cell function in insulin-treated diabetic patients assessed by C-peptide immunoreactivity.The New England journal of medicine, 288 22
R. Turner, S. Mccarthy, R. Holman, E. Harris (1976)
Beta-cell function improved by supplementing basal insulin secretion in mild diabetes.British Medical Journal, 1
W. Tamborlane, R. Sherwin, M. Genel, P. Felig (1979)
RESTORATION OF NORMAL LIPID AND AMINOACID METABOLISM IN DIABETIC PATIENTS TREATED WITH A PORTABLE INSULIN-INFUSION PUMPThe Lancet, 313
M. Belmonte, E. Sarkozy, E. Harpur (1967)
Urine Sugar Determination by the Two-drop Clinitest MethodDiabetes, 16
Heding LG Ludvigsson J (1977)
C-peptide in juvenile diabetics beyond the postinitial remission periodActa Paediatr Scand, 66
Horwitz DL Kuzuya H (1974)
Blood sugar control in insulin requiring diabetics: Relationship of exogenous and endogenous insulin, abstractedClin Res, 22
Lørup B Deckert T (1976)
Regulation of brittle diabetics by a preplanned insulin infusion programmeDiabetologia, 12
Diane Fabiny, G. Ertingshausen (1971)
Automated reaction-rate method for determination of serum creatinine with the CentrifiChem.Clinical chemistry, 17 8
D. Horwitz, A. Rubenstein, M. Mako, A. Cruz, P. Blix (1978)
C-Peptide in Conditions Other Than Diabetes MellitusDiabetes, 27
Tina LU Papadopoulou ZL (1978)
Children Are Different: Developmental Physiology
J. Pickup, H. Keen, J. Parsons, K. Alberti, A. Rowe (1979)
CONTINUOUS SUBCUTANEOUS INSULIN INFUSION: IMPROVED BLOOD-GLUCOSE AND INTERMEDIARY-METABOLITE CONTROL IN DIABETICSThe Lancet, 313
(1979)
New insulin-delivery systems for diabeticsLancet, 1
Binder C Faber OK (1977)
β-Cell function and blood glucose control in insulin-dependent diabetics within the first month of insulin treatmentDiabetologia, 13
Heding LG Ludvigsson J (1976)
C-peptide in children with juvenile diabetes: A preliminary reportDiabetologia, 12
Hewett JE Jackson RL (1978)
Objective criteria for classifying degree of control in children with insulin dependent diabetesDiabetes, 27
S. Genuth (1977)
Insulin secretion in obesity and diabetes: an illustrative case.Annals of internal medicine, 87 6
D. Horwitz, A. Rubenstein, A. Katz (1977)
Quantitation of Human Pancreatic Beta-cell Function by Immunoassay of C-Peptide in UrineDiabetes, 26
L. Trivelli, H. Ranney, H. Lai (1971)
Hemoglobin components in patients with diabetes mellitus.The New England journal of medicine, 284 7
Murthy DYN Jackson RL (1974)
Importance of early insulin treatment and good regulation of children with diabetesMo Med, 71
Rasmussen SM Heding LG (1975)
Human C-peptide in normal and diabetic subjectsDiabetologia, 11
K. Gabbay, Karen Hasty, J. Breslow, R. Ellison, H. Bunn, P. Gallop (1977)
Glycosylated hemoglobins and long-term blood glucose control in diabetes mellitus.The Journal of clinical endocrinology and metabolism, 44 5
Selam JL Mirouze J (1978)
Sustained insulin-induced remissions of juvenile diabetes by means of an external artificial pancreasDiabetologia, 14
Jackson Rl, M. Dy (1974)
Importance of early insulin treatment and good regulation of children with diabetes.Missouri medicine, 71
Guthrie RA Jackson RL (1972)
The child with diabetesMo Med, 69
Jackson Rl, Guthrie Ra (1972)
The child with diabetes.Missouri medicine, 69
C. Morgan, A. Lazarow (1963)
Immunoassay of Insulin: Two Antibody System: Plasma Insulin Levels of Normal, Subdiabetic and Diabetic RatsDiabetes, 12
L. Grajwer, R. Pildes, D. Horwitz, A. Rubenstein (1977)
Control of juvenile diabetes mellitus and its relationship to endogenous insulin secretion as measured by C-peptide immunoreactivity.The Journal of pediatrics, 90 1
Lazarow A Morgan CR (1963)
Immunoassay of insulin: Two antibody systemDiabetes, 12
S. Nakagawa, H. Nakayama, Takashi Sasaki, K. Yoshino, Yune Yu, K. Shinozaki, S. Aoki, K. Mashimo (1973)
A Simple Method for the Determination of Serum Free Insulin Levels in Insulin-treated PatientsDiabetes, 22
Abstract • Urinary C-peptide excretion was investigated as a method for monitoring β-cell function in diabetic patients and for studying the contribution of endogenous insulin production to diabetic control. Control subjects had variations in serum and urine C-peptide immunoreactivity that correlated with basal and meal-related insulin secretion. In a group of well-controlled juvenile diabetic patients, those receiving high doses of insulin had low or negligible C-peptide excretion, whereas most patients with low exogenous insulin requirements had near-normal urinary C-peptide excretion. Patients treated for diabetic ketoacidosis had recovery of β-cell function as measured by C-peptide immunoreactivity in serial urine specimens. Thus, measurement of urinary C-peptide excretion is a simple technique that may be useful in assessing endogenous insulin production in juvenile diabetic patients. (Am J Dis Child 134:1129-1133, 1980) References 1. Block MB, Rosenfield RL, Mako ME, et al: Sequential changes in β-cell function in insulin-treated diabetic patients assessed by C-peptide immunoreactivity . N Engl J Med 288:1144-1148, 1973.Crossref 2. Faber OK, Binder C: β-Cell function and blood glucose control in insulin-dependent diabetics within the first month of insulin treatment . Diabetologia 13:263-268, 1977.Crossref 3. Grajwer LA, Pildes RS, Horwitz DL, et al: Control of juvenile diabetes mellitus and its relationship to endogenous insulin secretion as measured by C-peptide immunoreactivity . J Pediatr 90:42-48, 1977.Crossref 4. Heding LG, Rasmussen SM: Human C-peptide in normal and diabetic subjects . Diabetologia 11:201-206, 1975.Crossref 5. Ludvigsson J, Heding LG: C-peptide in children with juvenile diabetes: A preliminary report . Diabetologia 12:627-630, 1976.Crossref 6. Ludvigsson J, Heding LG, Larsson Y, et al: C-peptide in juvenile diabetics beyond the postinitial remission period . Acta Paediatr Scand 66:177-184, 1977.Crossref 7. Madsbad S, Faber OK, Binder C, et al: Prevalence of residual β-cell function in insulin-dependent diabetics in relation to age at onset and duration of diabetes . Diabetes 27:262-264, 1978.Crossref 8. Horwitz DL, Rubenstein AH, Katz AI: Quantitation of human pancreatic β-cell function by immunoassay of C-peptide in urine . Diabetes 26:30-35, 1977.Crossref 9. Horwitz DL, Rubenstein AH, Mako ME, et al: C-peptide in conditions other than diabetes mellitus . Diabetes 27:267-271, 1978.Crossref 10. Fabiny DL, Ertingshausen G: Automated reaction rate method for determination of creatinine with the centrifichem . Clin Chem 17:696-700, 1971. 11. Trivelli LA, Ranney HM, Lai HT: Hemoglobin components in patients with diabetes mellitus . N Engl J Med 284:353-357, 1971.Crossref 12. Gabbay KG, Hasty K, Breslow JL, et al: Glycosylated hemoglobins and long-term blood glucose control in diabetes mellitus . J Clin Endocrinol Metab 44:859-864, 1977.Crossref 13. Nakagawa S, Nakayama H, Saski T, et al: A simple method for the determination of serum free insulin levels in insulin treated patients . Diabetes 22:590-600, 1973. 14. Belmonte MM, Sarkozy E, Harpur ER: Urine sugar determination by the two-drop Clinitest method . Diabetes 16:557-559, 1967. 15. Morgan CR, Lazarow A: Immunoassay of insulin: Two antibody system . Diabetes 12:115-126, 1963. 16. Papadopoulou ZL, Tina LU, Sandler P, et al: Size and function of the kidneys , in Johnson TR, Moore WM, Jeffries JE (eds): Children Are Different: Developmental Physiology . Columbus, Ohio, Ross Laboratories, 1978, p 99. 17. Jackson RL, Guthrie RA: The child with diabetes . Mo Med 69:351-358, 1972. 18. Kuzuya H, Horwitz DL, Stelling M, et al: Blood sugar control in insulin requiring diabetics: Relationship of exogenous and endogenous insulin, abstracted . Clin Res 22:618A, 1974. 19. Jackson RL, Hewett JE, Hess RL, et al: Objective criteria for classifying degree of control in children with insulin dependent diabetes , abstract No. 54. Diabetes 27:444, 1978. 20. Turner RC, McCarthy ST, Holman RR, et al: β-Cell function improved by supplementing basal insulin secretion in mild diabetes . Br Med J 1:1252-1254, 1976.Crossref 21. Mirouze J, Selam JL, Pham TC, et al: Sustained insulin-induced remissions of juvenile diabetes by means of an external artificial pancreas . Diabetologia 14:223-227, 1978.Crossref 22. Genuth SM: Insulin secretion in obesity and diabetes: An illustrative case . Ann Intern Med 87:714-716, 1977.Crossref 23. Jackson RL, Murthy DYN: Importance of early insulin treatment and good regulation of children with diabetes . Mo Med 71:173-176, 1974. 24. New insulin-delivery systems for diabetics , editorial. Lancet 1:1275-1277, 1979. 25. Pickup JC, Keen H, Parsons JA, et al: Continuous subcutaneous insulin infusion: Improved blood-glucose and intermediary-metabolite control in diabetics . Lancet 1:1255-1257, 1979.Crossref 26. Tamborlane WV, Sherwin RS, Genel M, et al: Restoration of normal lipid and aminoacid metabolism in diabetic patients treated with a portable insulin-infusion pump . Lancet 1:1258-1261, 1979.Crossref 27. Deckert T, Lørup B: Regulation of brittle diabetics by a preplanned insulin infusion programme . Diabetologia 12:573-579, 1976.Crossref
American Journal of Diseases of Children – American Medical Association
Published: Dec 1, 1980
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