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Unusual Multiply Resistant Pneumococci-Reply

Unusual Multiply Resistant Pneumococci-Reply Abstract In Reply.—Drs Conde-Glez and Calderon are uncertain about the number of MRPS pneumococci isolated at daycare centers. Twenty strains of multiply resistant pneumococci were isolated (from 7.9% of the children). Minimum inhibitory concentrations were determined for penicillin, tetracycline, erythromycin, clindamycin, and the combination product of trimethoprim and sulfamethoxazole against all these strains. Fifteen strains were tested against ten additional antibiotics, and these data were presented in Table 3 of our report. Minimum inhibitory concentrations of penicillin were thus performed for all 20 isolates, not just 15 strains as suggested by Drs Conde-Glez and Calderon. Table 2 gives data for three strains that showed penicillin resistance. These were among the 20 multiply resistant strains isolated but were not MRPS pneumococci by definition. These strains were identified as penicillin resistant by MICs and because their methicillin disk zone sizes were less than 25 mm. The false susceptibility rate of 20% (three References 1. Jacobs MR, Gaspar MN, Robins-Browne RM, et al: Antimicrobial susceptibility testing of pneumococci: II. Determination of optimal disc diffusion test for detection of penicillin G resistance . J Antimicrob Chemother 1980;6:53-64.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

Unusual Multiply Resistant Pneumococci-Reply

Abstract

Abstract In Reply.—Drs Conde-Glez and Calderon are uncertain about the number of MRPS pneumococci isolated at daycare centers. Twenty strains of multiply resistant pneumococci were isolated (from 7.9% of the children). Minimum inhibitory concentrations were determined for penicillin, tetracycline, erythromycin, clindamycin, and the combination product of trimethoprim and sulfamethoxazole against all these strains. Fifteen strains were tested against ten additional antibiotics, and these...
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References (1)

Publisher
American Medical Association
Copyright
Copyright © 1988 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1988.02150030019009
Publisher site
See Article on Publisher Site

Abstract

Abstract In Reply.—Drs Conde-Glez and Calderon are uncertain about the number of MRPS pneumococci isolated at daycare centers. Twenty strains of multiply resistant pneumococci were isolated (from 7.9% of the children). Minimum inhibitory concentrations were determined for penicillin, tetracycline, erythromycin, clindamycin, and the combination product of trimethoprim and sulfamethoxazole against all these strains. Fifteen strains were tested against ten additional antibiotics, and these data were presented in Table 3 of our report. Minimum inhibitory concentrations of penicillin were thus performed for all 20 isolates, not just 15 strains as suggested by Drs Conde-Glez and Calderon. Table 2 gives data for three strains that showed penicillin resistance. These were among the 20 multiply resistant strains isolated but were not MRPS pneumococci by definition. These strains were identified as penicillin resistant by MICs and because their methicillin disk zone sizes were less than 25 mm. The false susceptibility rate of 20% (three References 1. Jacobs MR, Gaspar MN, Robins-Browne RM, et al: Antimicrobial susceptibility testing of pneumococci: II. Determination of optimal disc diffusion test for detection of penicillin G resistance . J Antimicrob Chemother 1980;6:53-64.Crossref

Journal

American Journal of Diseases of ChildrenAmerican Medical Association

Published: Mar 1, 1988

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