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Unsuspected Malignant Melanoma: Enucleation Following Trauma and Endophthalmitis

Unsuspected Malignant Melanoma: Enucleation Following Trauma and Endophthalmitis Abstract Ten percent of choroidal malignant melanomas diagnosed microscopically are unsuspected.1 Advanced glaucoma is the reason for enucleation in over 90% of such cases. About 25% of these unsuspected tumors are markedly necrotic; they are often manifested clinically by signs of a severe uveitis, endophthalmitis, or panophthalmitis. Phthisical eyes, blind for years and removed for cosmetic reasons, occasionally contain a malignant melanoma.2 Acute trauma, on the other hand, is an unusual cause for enucleation of an eye that contains a malignant melanoma. The purpose of this report is to record such a case. Report of a Case A 53-year-old white woman was examined because of an inflamed right eye. There was extensive chemosis, and conjunctival tissue appeared to have grown over the cornea. The globe was hard, and there was no light perception. Although no wound was apparent, a penetrating injury was thought to have occurred several weeks earlier. References 1. Kirk, H.Q., and Petty, R.W.: Malignant Melanoma of the Choroid: A Correlation of Clinical and Histopathologic Findings , Arch Ophthal 56:843-860, 1956.Crossref 2. Hogan, M.J., and Zimmerman, L.E.: Ophthalmic Pathology , Philadelphia: W. B. Saunders Co., 1962. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Unsuspected Malignant Melanoma: Enucleation Following Trauma and Endophthalmitis

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Publisher
American Medical Association
Copyright
Copyright © 1966 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1966.03850010580017
Publisher site
See Article on Publisher Site

Abstract

Abstract Ten percent of choroidal malignant melanomas diagnosed microscopically are unsuspected.1 Advanced glaucoma is the reason for enucleation in over 90% of such cases. About 25% of these unsuspected tumors are markedly necrotic; they are often manifested clinically by signs of a severe uveitis, endophthalmitis, or panophthalmitis. Phthisical eyes, blind for years and removed for cosmetic reasons, occasionally contain a malignant melanoma.2 Acute trauma, on the other hand, is an unusual cause for enucleation of an eye that contains a malignant melanoma. The purpose of this report is to record such a case. Report of a Case A 53-year-old white woman was examined because of an inflamed right eye. There was extensive chemosis, and conjunctival tissue appeared to have grown over the cornea. The globe was hard, and there was no light perception. Although no wound was apparent, a penetrating injury was thought to have occurred several weeks earlier. References 1. Kirk, H.Q., and Petty, R.W.: Malignant Melanoma of the Choroid: A Correlation of Clinical and Histopathologic Findings , Arch Ophthal 56:843-860, 1956.Crossref 2. Hogan, M.J., and Zimmerman, L.E.: Ophthalmic Pathology , Philadelphia: W. B. Saunders Co., 1962.

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Oct 1, 1966

References

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