Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Unilateral Adrenal Catecholamine Excess: Pheochromocytoma or Possible Sporadic Medullary Hyperplasia

Unilateral Adrenal Catecholamine Excess: Pheochromocytoma or Possible Sporadic Medullary Hyperplasia Abstract • A 60-year-old man had clinical and biochemical evidence of pheochromocytoma. Venous blood from the left adrenal gland had strikingly higher concentrations of l-norepinephrine, epinephrine, and dopamine than that from the right adrenal gland. The patient's condition was cured following left adrenalectomy. Pathologic examination of the left adrenal gland did not reveal either pheochromocytoma or medullary hyperplasia but rather hemorrhagic degeneration of the medulla of an enlarged adrenal gland. Although only one adrenal gland was removed, Addison's disease developed. (Arch Intern Med 1982;142:377-378) References 1. Melicow MM: One hundred cases of pheochromocytoma (107 tumors) at the Columbia-Presbyterian Medical Center: 1926-1976. Cancer 1977;40:1987-2004.Crossref 2. Drukker W, Formijne P, vdSchoot JB: Hyperplasia of the adrenal medulla. Br Med J 1957;1:186-189.Crossref 3. Montalbano FP, Baronofsky ID, Ball H: Hyperplasia of the adrenal medulla. JAMA 1962;182:264-267.Crossref 4. Carney JA, Sizemore GW, Tyce GM: Bilateral adrenal medullary hyperplasia in multiple endocrine neoplasia, type 2. Mayo Clin Proc 1975;50:3-10. 5. Carney JA, Sizemore GW, Sheps SG: Adrenal medullary disease in multiple endocrine neoplasia, type 2. Am J Clin Pathol 1976;66:279-290. 6. Gagel RF, Melvin KEW, Tashjian AH Jr, et al: Natural history of the familial medullary thyroid carcinoma-pheochromocytoma syndrome and the identification of preneoplastic stages by screening studies: A five-year report. Trans Assoc Am Physicians 1975;88:177-191. 7. Webb TA, Sheps SG, Carney JA: Differences between sporadic pheochromocytoma and pheochromocytoma in multiple endocrine neoplasia, type 2. Am J Surg Pathol 1980;4:121-126.Crossref 8. Liddle GW: The adrenal cortex: Part 1 , in Williams RH (ed): Textbook of Endocrinology , ed 5. Philadelphia, WB Saunders Co, 1974, pp 233-283. 9. Harrison TS, Freier DT: Pitfalls in the technique and interpretation of regional venous sampling for localizing pheochromocytoma. Surg Clin North Am 1974;54:339-347. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

Unilateral Adrenal Catecholamine Excess: Pheochromocytoma or Possible Sporadic Medullary Hyperplasia

Archives of Internal Medicine , Volume 142 (2) – Feb 1, 1982

Loading next page...
 
/lp/american-medical-association/unilateral-adrenal-catecholamine-excess-pheochromocytoma-or-possible-dWay82hX1q
Publisher
American Medical Association
Copyright
Copyright © 1982 American Medical Association. All Rights Reserved.
ISSN
0003-9926
eISSN
1538-3679
DOI
10.1001/archinte.1982.00340150177031
Publisher site
See Article on Publisher Site

Abstract

Abstract • A 60-year-old man had clinical and biochemical evidence of pheochromocytoma. Venous blood from the left adrenal gland had strikingly higher concentrations of l-norepinephrine, epinephrine, and dopamine than that from the right adrenal gland. The patient's condition was cured following left adrenalectomy. Pathologic examination of the left adrenal gland did not reveal either pheochromocytoma or medullary hyperplasia but rather hemorrhagic degeneration of the medulla of an enlarged adrenal gland. Although only one adrenal gland was removed, Addison's disease developed. (Arch Intern Med 1982;142:377-378) References 1. Melicow MM: One hundred cases of pheochromocytoma (107 tumors) at the Columbia-Presbyterian Medical Center: 1926-1976. Cancer 1977;40:1987-2004.Crossref 2. Drukker W, Formijne P, vdSchoot JB: Hyperplasia of the adrenal medulla. Br Med J 1957;1:186-189.Crossref 3. Montalbano FP, Baronofsky ID, Ball H: Hyperplasia of the adrenal medulla. JAMA 1962;182:264-267.Crossref 4. Carney JA, Sizemore GW, Tyce GM: Bilateral adrenal medullary hyperplasia in multiple endocrine neoplasia, type 2. Mayo Clin Proc 1975;50:3-10. 5. Carney JA, Sizemore GW, Sheps SG: Adrenal medullary disease in multiple endocrine neoplasia, type 2. Am J Clin Pathol 1976;66:279-290. 6. Gagel RF, Melvin KEW, Tashjian AH Jr, et al: Natural history of the familial medullary thyroid carcinoma-pheochromocytoma syndrome and the identification of preneoplastic stages by screening studies: A five-year report. Trans Assoc Am Physicians 1975;88:177-191. 7. Webb TA, Sheps SG, Carney JA: Differences between sporadic pheochromocytoma and pheochromocytoma in multiple endocrine neoplasia, type 2. Am J Surg Pathol 1980;4:121-126.Crossref 8. Liddle GW: The adrenal cortex: Part 1 , in Williams RH (ed): Textbook of Endocrinology , ed 5. Philadelphia, WB Saunders Co, 1974, pp 233-283. 9. Harrison TS, Freier DT: Pitfalls in the technique and interpretation of regional venous sampling for localizing pheochromocytoma. Surg Clin North Am 1974;54:339-347.

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Feb 1, 1982

References