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Ultraviolet-Laser Ablation of Skin

Ultraviolet-Laser Ablation of Skin Abstract • We report on the use of pulsed ultraviolet-laser irradiation at 193 nm from an argon-fluoride laser and at 248 nm from a krypton-fluoride laser to ablate skin. In vitro, both wavelengths performed comparably, removing tissue precisely and cleanly, and leaving minimal thermal damage to the surrounding tissue. In vivo, the 193-nm laser radiation failed to remove tissue after bleeding began. The 248-nm radiation, however, continued to remove tissue despite bleeding and left a clean incision with only minimal thermal damage. The krypton-fluoride excimer laser beam at 248 nm, which should be deliverable through a quartz optical fiber, has great potential as a surgical instrument. (Arch Dermatol 1985;121:609-617) References 1. Srinivasan R, Mayne-Banton V: Self-developing photoetching of poly(ethylene terephthalate) films by far-ultraviolet laser radiation . Appl Physics Lett 1982;41:576-578.Crossref 2. Srinivasan R, Leigh WJ: Ablative photodecomposition: Action of far-ultraviolet (193 nm) laser radiation on poly(ethylene terephthalate) films . J Am Chem Soc 1982;104:6784-6785.Crossref 3. Srinivasan R: Kinetics of the ablative photodecomposition of organic polymers in the far-ultraviolet (193 nm) . J Vacuum Sci Technol 1983;B1:923-926.Crossref 4. Srinivasan R, Wynne JJ, Blum SE: Far-UV photoetching of organic material . Laser Focus 1983;19( (May) ):62-66. 5. Linsker R, Srinivasan R, Wynne JJ, et al: Far-ultraviolet laser ablation of atherosclerotic lesions . Lasers Surg Med 1984; 4:201-206.Crossref 6. Trokel SL, Srinivasan R, Braren B: Excimer laser surgery of the cornea . Am J Ophthalmol 1983;96:710-715. 7. Rhodes CK (ed): Excimer Lasers , in Topics in Applied Physics . New York, Springer Publishing Co, 1979, vol 30. 8. McKee T, Nilson JA: Excimer applications . Laser Focus 1982; 18( (June) ):51-55. 9. Bailin PL: Use of the CO2 laser for non-PWS cutaneous lesions , in Arndt KA, Noe JM, Rosen S (eds): Cutaneous Laser Therapy: Principles and Methods . New York, John Wiley & Sons Inc, 1983, pp 187-199. 10. Rosen S: Vascular supply of normal skin and the comparative histologic effects of the tunable dye (at 577 nm) laser and argon laser on normal skin , in Arndt KA, Noe JM, Rosen S (eds): Cutaneous Laser Therapy: Principles and Methods . New York, John Wiley & Sons Inc, 1983, pp 53-63. 11. Rabinowitch E: Electron transfer spectra and their photochemical effect . Rev Mod Physics 1942;14:112-131.Crossref 12. Blandamer MJ, Fox MF: Theory and applications of chargetransfer-to-solvent spectra . Chem Rev 1970;70:59-93.Crossref 13. Parrish J, Anderson R: Considerations of selectivity in laser therapy , in Arndt KA, Noe JM, Rosen S (eds): Cutaneous Laser Therapy: Principles and Methods . New York, John Wiley & Sons Inc, 1983, pp 41-51. 14. Urbach F (ed): The Biological Effects of Ultraviolet Radiation (With Emphasis on the Skin) . New York, Pergamon Press, 1969. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

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Publisher
American Medical Association
Copyright
Copyright © 1985 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1985.01660050061016
Publisher site
See Article on Publisher Site

Abstract

Abstract • We report on the use of pulsed ultraviolet-laser irradiation at 193 nm from an argon-fluoride laser and at 248 nm from a krypton-fluoride laser to ablate skin. In vitro, both wavelengths performed comparably, removing tissue precisely and cleanly, and leaving minimal thermal damage to the surrounding tissue. In vivo, the 193-nm laser radiation failed to remove tissue after bleeding began. The 248-nm radiation, however, continued to remove tissue despite bleeding and left a clean incision with only minimal thermal damage. The krypton-fluoride excimer laser beam at 248 nm, which should be deliverable through a quartz optical fiber, has great potential as a surgical instrument. (Arch Dermatol 1985;121:609-617) References 1. Srinivasan R, Mayne-Banton V: Self-developing photoetching of poly(ethylene terephthalate) films by far-ultraviolet laser radiation . Appl Physics Lett 1982;41:576-578.Crossref 2. Srinivasan R, Leigh WJ: Ablative photodecomposition: Action of far-ultraviolet (193 nm) laser radiation on poly(ethylene terephthalate) films . J Am Chem Soc 1982;104:6784-6785.Crossref 3. Srinivasan R: Kinetics of the ablative photodecomposition of organic polymers in the far-ultraviolet (193 nm) . J Vacuum Sci Technol 1983;B1:923-926.Crossref 4. Srinivasan R, Wynne JJ, Blum SE: Far-UV photoetching of organic material . Laser Focus 1983;19( (May) ):62-66. 5. Linsker R, Srinivasan R, Wynne JJ, et al: Far-ultraviolet laser ablation of atherosclerotic lesions . Lasers Surg Med 1984; 4:201-206.Crossref 6. Trokel SL, Srinivasan R, Braren B: Excimer laser surgery of the cornea . Am J Ophthalmol 1983;96:710-715. 7. Rhodes CK (ed): Excimer Lasers , in Topics in Applied Physics . New York, Springer Publishing Co, 1979, vol 30. 8. McKee T, Nilson JA: Excimer applications . Laser Focus 1982; 18( (June) ):51-55. 9. Bailin PL: Use of the CO2 laser for non-PWS cutaneous lesions , in Arndt KA, Noe JM, Rosen S (eds): Cutaneous Laser Therapy: Principles and Methods . New York, John Wiley & Sons Inc, 1983, pp 187-199. 10. Rosen S: Vascular supply of normal skin and the comparative histologic effects of the tunable dye (at 577 nm) laser and argon laser on normal skin , in Arndt KA, Noe JM, Rosen S (eds): Cutaneous Laser Therapy: Principles and Methods . New York, John Wiley & Sons Inc, 1983, pp 53-63. 11. Rabinowitch E: Electron transfer spectra and their photochemical effect . Rev Mod Physics 1942;14:112-131.Crossref 12. Blandamer MJ, Fox MF: Theory and applications of chargetransfer-to-solvent spectra . Chem Rev 1970;70:59-93.Crossref 13. Parrish J, Anderson R: Considerations of selectivity in laser therapy , in Arndt KA, Noe JM, Rosen S (eds): Cutaneous Laser Therapy: Principles and Methods . New York, John Wiley & Sons Inc, 1983, pp 41-51. 14. Urbach F (ed): The Biological Effects of Ultraviolet Radiation (With Emphasis on the Skin) . New York, Pergamon Press, 1969.

Journal

Archives of DermatologyAmerican Medical Association

Published: May 1, 1985

References