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TWO YEARS' EXPERIENCE WITH CHEMOPALLIDECTOMY

TWO YEARS' EXPERIENCE WITH CHEMOPALLIDECTOMY Fifty-three patients underwent chemopallidectomy as treatment for dystonias believed to originate in the basal ganglions. In 43 the symptoms were those of Parkinsonism. The procedure consisted in passing a catheter through an incision and bur hole just superior to the zygomatic process of the temporal bone. The catheter was timed directly at the roof of the third ventricle and advanced until its tip would deliver injected materials (ethylcellulose and ethyl alcohol) 1.5 cm. lateral to the wall of the third ventricle. Two components of Parkinsonism were considerably reduced by the operation, namely the plastic rigidity and the pill-rolling tremor. But the patients could be easily identified as having Parkinsonism after operation, and none of them reestablished a wholly normal synergistic motor pattern. Patients with congenital athetosis and spasmodic torticollis were not helped, but good results were obtained in two with dystonia musculorum deformans and three with acquired choreiform movements. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

TWO YEARS' EXPERIENCE WITH CHEMOPALLIDECTOMY

JAMA , Volume 168 (6) – Oct 11, 1958

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References (4)

Publisher
American Medical Association
Copyright
Copyright © 1958 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1958.03000060039009
Publisher site
See Article on Publisher Site

Abstract

Fifty-three patients underwent chemopallidectomy as treatment for dystonias believed to originate in the basal ganglions. In 43 the symptoms were those of Parkinsonism. The procedure consisted in passing a catheter through an incision and bur hole just superior to the zygomatic process of the temporal bone. The catheter was timed directly at the roof of the third ventricle and advanced until its tip would deliver injected materials (ethylcellulose and ethyl alcohol) 1.5 cm. lateral to the wall of the third ventricle. Two components of Parkinsonism were considerably reduced by the operation, namely the plastic rigidity and the pill-rolling tremor. But the patients could be easily identified as having Parkinsonism after operation, and none of them reestablished a wholly normal synergistic motor pattern. Patients with congenital athetosis and spasmodic torticollis were not helped, but good results were obtained in two with dystonia musculorum deformans and three with acquired choreiform movements.

Journal

JAMAAmerican Medical Association

Published: Oct 11, 1958

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