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TROPHOBLASTIC PULMONARY THROMBOSIS WITH COR PULMONALE

TROPHOBLASTIC PULMONARY THROMBOSIS WITH COR PULMONALE The patient's first pregnancy, in 1953, terminated at five and one-half months with the expulsion of a mass that was described, on the basis of microscopic examination, as a benign hydatiform mole. Five years later, after repeated pulmonary complaints, the patient was found to have infiltration of the left lung field and left pleural effusion. After hospitalization, her condition deteriorated steadily. Postmortem examination confirmed the clinical impression of multiple pulmonary infarction and cor pulmonale. The infarcts were due to choriocarcinomatous tumor thrombi originating from a Y-shaped saddle type of trophoblastic tumor obstructing the pulmonary arteries bilaterally. It is unlikely that administration of chorionic gonadotropin to the patient in the five-year interval for infertility stimulated trophoblastic proliferation, but this possibility cannot be entirely excluded. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

TROPHOBLASTIC PULMONARY THROMBOSIS WITH COR PULMONALE

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Publisher
American Medical Association
Copyright
Copyright © 1959 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1959.03010160014005
Publisher site
See Article on Publisher Site

Abstract

The patient's first pregnancy, in 1953, terminated at five and one-half months with the expulsion of a mass that was described, on the basis of microscopic examination, as a benign hydatiform mole. Five years later, after repeated pulmonary complaints, the patient was found to have infiltration of the left lung field and left pleural effusion. After hospitalization, her condition deteriorated steadily. Postmortem examination confirmed the clinical impression of multiple pulmonary infarction and cor pulmonale. The infarcts were due to choriocarcinomatous tumor thrombi originating from a Y-shaped saddle type of trophoblastic tumor obstructing the pulmonary arteries bilaterally. It is unlikely that administration of chorionic gonadotropin to the patient in the five-year interval for infertility stimulated trophoblastic proliferation, but this possibility cannot be entirely excluded.

Journal

JAMAAmerican Medical Association

Published: Aug 15, 1959

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