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'Tricks' of trade aid kidney transplants

'Tricks' of trade aid kidney transplants This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract Monoclonal antibodies directed against specific T-lymphocyte antigens, donor-specific blood transfusions, and cyclosporine are permitting many patients to be successfully transplanted with poorly matched kidneys, according to reports at a recent National Kidney Foundation meeting in Washington, DC. Thus, use of these methods is further improving graft survival rates. (Even between 1977 and 1980—before these methods came into general use—graft survival rates increased substantially. In an interview with JAMA MEDICAL NEWS, Henry Krakauer, MD, PhD, noted that rates increased from 52% to 61% at one year for cadaveric transplants and from 70% to 82% for grafts from living related donors. Krakauer, of the Genetics and Transplantation Branch, National Institute of Allergy and Infectious Diseases, Bethesda, Md, derived his figures from various sources, including raw data from the Health Care Financing Administration.) Because mature T lymphocytes appear to be the principal effector cells in most cases of graft rejection, eliminating or suppressing http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

'Tricks' of trade aid kidney transplants

JAMA , Volume 249 (17) – May 6, 1983

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Publisher
American Medical Association
Copyright
Copyright © 1983 American Medical Association. All Rights Reserved.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1983.03330410004002
Publisher site
See Article on Publisher Site

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract Monoclonal antibodies directed against specific T-lymphocyte antigens, donor-specific blood transfusions, and cyclosporine are permitting many patients to be successfully transplanted with poorly matched kidneys, according to reports at a recent National Kidney Foundation meeting in Washington, DC. Thus, use of these methods is further improving graft survival rates. (Even between 1977 and 1980—before these methods came into general use—graft survival rates increased substantially. In an interview with JAMA MEDICAL NEWS, Henry Krakauer, MD, PhD, noted that rates increased from 52% to 61% at one year for cadaveric transplants and from 70% to 82% for grafts from living related donors. Krakauer, of the Genetics and Transplantation Branch, National Institute of Allergy and Infectious Diseases, Bethesda, Md, derived his figures from various sources, including raw data from the Health Care Financing Administration.) Because mature T lymphocytes appear to be the principal effector cells in most cases of graft rejection, eliminating or suppressing

Journal

JAMAAmerican Medical Association

Published: May 6, 1983

There are no references for this article.