Key PointsQuestionHow has reperfusion therapy for in-hospital onset of ischemic stroke changed in the endovascular era? FindingsThis cohort study of 2 237 793 patients found that in-hospital stroke onset was increasingly reported. Endovascular therapy use steadily increased after 2015, whereas the rate of intravenous thrombolysis use doubled since 2008; however, patients with in-hospital stroke onset underwent intravenous thrombolysis and endovascular therapies at significantly slower rates with worse functional outcomes than those with out-of-hospital onset. MeaningAlthough patients with in-hospital stroke onset were increasingly reported and treated with reperfusion therapy, disparities in care persisted, highlighting opportunities to further care for these patients, including the use of dedicated inpatient stroke protocols to bridge this disparity in stroke care.
JAMA Neurology – American Medical Association
Published: Dec 21, 2020