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Trends in Reperfusion Therapy for In-Hospital Ischemic Stroke in the Endovascular Therapy Era

Trends in Reperfusion Therapy for In-Hospital Ischemic Stroke in the Endovascular Therapy Era Key PointsQuestionHow has reperfusion therapy for in-hospital onset of ischemic stroke changed in the endovascular era? FindingsThis cohort study of 2 237 793 patients found that in-hospital stroke onset was increasingly reported. Endovascular therapy use steadily increased after 2015, whereas the rate of intravenous thrombolysis use doubled since 2008; however, patients with in-hospital stroke onset underwent intravenous thrombolysis and endovascular therapies at significantly slower rates with worse functional outcomes than those with out-of-hospital onset. MeaningAlthough patients with in-hospital stroke onset were increasingly reported and treated with reperfusion therapy, disparities in care persisted, highlighting opportunities to further care for these patients, including the use of dedicated inpatient stroke protocols to bridge this disparity in stroke care. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Neurology American Medical Association

Trends in Reperfusion Therapy for In-Hospital Ischemic Stroke in the Endovascular Therapy Era

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Publisher
American Medical Association
Copyright
Copyright 2020 American Medical Association. All Rights Reserved.
ISSN
2168-6149
eISSN
2168-6157
DOI
10.1001/jamaneurol.2020.3362
Publisher site
See Article on Publisher Site

Abstract

Key PointsQuestionHow has reperfusion therapy for in-hospital onset of ischemic stroke changed in the endovascular era? FindingsThis cohort study of 2 237 793 patients found that in-hospital stroke onset was increasingly reported. Endovascular therapy use steadily increased after 2015, whereas the rate of intravenous thrombolysis use doubled since 2008; however, patients with in-hospital stroke onset underwent intravenous thrombolysis and endovascular therapies at significantly slower rates with worse functional outcomes than those with out-of-hospital onset. MeaningAlthough patients with in-hospital stroke onset were increasingly reported and treated with reperfusion therapy, disparities in care persisted, highlighting opportunities to further care for these patients, including the use of dedicated inpatient stroke protocols to bridge this disparity in stroke care.

Journal

JAMA NeurologyAmerican Medical Association

Published: Dec 21, 2020

References