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Treatments for Centruroides exilicauda Envenomation

Treatments for Centruroides exilicauda Envenomation Abstract • We treated two cases of severe envenomation by the scorpion Centruroides exilicauda. The first infant was treated with a species-specific scorpion antivenom, which produced a delayed but dramatic return of all vital signs to normal. A second infant was treated with two doses of intravenous propranolol hydrochloride and had a rapid, dramatic decrease in heart rate but only gradual resolution of neurologic symptoms. These cases demonstrate the severe symptoms of envenomation by this scorpion in the infant and show two possible treatments. (AJDC 1984;138:1136-1139) References 1. Stahnke HL: The genus Centruroides (Buthidae) and its venom , in Bettini S (ed): Arthropod Venom . New York, Springer Publishing Co Inc, 1978, vol 48, pp 277-307. 2. Likes KE, Banner W Jr, Chavez ML: Centruroides exilicauda envenomation in Arizona. West J Med, in press. 3. Zlotkin E, Miranda F, Rochat H: Chemistry and pharmacology of Buthidae scorpion venoms , in Bettini S (ed): Arthropod Venom . New York, Springer Publishing Co Inc, 1978, vol 48, pp 317-369. 4. Wang GK, Strichartz GR: Purification and physiological characterization of neurotoxins from venom of the scorpions Centruroides sculpturatus and Leiuvus quinquestriatus . Mol Pharmacol 1983;23:519-533. 5. Yarom R: Scorpion venom: A tutorial review of its effects in men and experimental animals . Clin Toxicol 1970;3:561-569.Crossref 6. Rimsza ME, Zimmerman DR, Bergeson PS: Scorpion envenomation . Pediatrics 1980; 66:298-302. 7. LaGrange RG: Elevation of blood pressure and plasma renin levels by venom from scorpions, Centruroides sculpturatus and Leiuvus quinquestriatus . Toxicon 1977;15:429-433.Crossref 8. Stahnke HL: Arizona's lethal scorpion . Ariz Med 1972;29:490-493. 9. Stahnke HL: The Arizona scorpion problem . Ariz Med 1950;7:23-29. 10. Stahnke HL: Hypothermia and scorpion venomation . SW Med 1965;49:286-287. 11. Stahnke HL: The treatment of scorpion sting . Ariz Med 1957;14:576-580. 12. Scorpion antivenom (lyophilized) package insert. Tempe, Ariz, Iatric Laboratories, 1973. 13. Gueron M, Adolph RJ, Grupp IL, et al: Hemodynamic and myocardial consequences of scorpion venom . Am J Cardiol 1980;45:979-986.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

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Publisher
American Medical Association
Copyright
Copyright © 1984 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1984.02140500042015
Publisher site
See Article on Publisher Site

Abstract

Abstract • We treated two cases of severe envenomation by the scorpion Centruroides exilicauda. The first infant was treated with a species-specific scorpion antivenom, which produced a delayed but dramatic return of all vital signs to normal. A second infant was treated with two doses of intravenous propranolol hydrochloride and had a rapid, dramatic decrease in heart rate but only gradual resolution of neurologic symptoms. These cases demonstrate the severe symptoms of envenomation by this scorpion in the infant and show two possible treatments. (AJDC 1984;138:1136-1139) References 1. Stahnke HL: The genus Centruroides (Buthidae) and its venom , in Bettini S (ed): Arthropod Venom . New York, Springer Publishing Co Inc, 1978, vol 48, pp 277-307. 2. Likes KE, Banner W Jr, Chavez ML: Centruroides exilicauda envenomation in Arizona. West J Med, in press. 3. Zlotkin E, Miranda F, Rochat H: Chemistry and pharmacology of Buthidae scorpion venoms , in Bettini S (ed): Arthropod Venom . New York, Springer Publishing Co Inc, 1978, vol 48, pp 317-369. 4. Wang GK, Strichartz GR: Purification and physiological characterization of neurotoxins from venom of the scorpions Centruroides sculpturatus and Leiuvus quinquestriatus . Mol Pharmacol 1983;23:519-533. 5. Yarom R: Scorpion venom: A tutorial review of its effects in men and experimental animals . Clin Toxicol 1970;3:561-569.Crossref 6. Rimsza ME, Zimmerman DR, Bergeson PS: Scorpion envenomation . Pediatrics 1980; 66:298-302. 7. LaGrange RG: Elevation of blood pressure and plasma renin levels by venom from scorpions, Centruroides sculpturatus and Leiuvus quinquestriatus . Toxicon 1977;15:429-433.Crossref 8. Stahnke HL: Arizona's lethal scorpion . Ariz Med 1972;29:490-493. 9. Stahnke HL: The Arizona scorpion problem . Ariz Med 1950;7:23-29. 10. Stahnke HL: Hypothermia and scorpion venomation . SW Med 1965;49:286-287. 11. Stahnke HL: The treatment of scorpion sting . Ariz Med 1957;14:576-580. 12. Scorpion antivenom (lyophilized) package insert. Tempe, Ariz, Iatric Laboratories, 1973. 13. Gueron M, Adolph RJ, Grupp IL, et al: Hemodynamic and myocardial consequences of scorpion venom . Am J Cardiol 1980;45:979-986.Crossref

Journal

American Journal of Diseases of ChildrenAmerican Medical Association

Published: Dec 1, 1984

References

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