Treatment of Water Intoxication With Mannitol-Reply
Abstract
Abstract In Reply.—Since water intoxication has been a rare entity, it is not surprising that studies providing critical comparison of hypertonic saline vs mannitol have not been published. I agree with Nutman and Hill that mannitol is a reasonable choice, but it has not been proven to be safer or more effective. Although discussion of refinements of therapy is interesting, prevention is a more attractive topic. Interventions directed to the population at risk might include education,...