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Treatment of Viral Warts With Pressure-Sensitive Adhesive Tape Containing Bleomycin Sulfate

Treatment of Viral Warts With Pressure-Sensitive Adhesive Tape Containing Bleomycin Sulfate Abstract To the Editor.— The currently employed manipulations for the treatment of common and plantar warts depend mainly on physical and chemical destruction of the warts.1,2 One of the disadvantages in these maneuvers is associated pain at the treated site. Herein, we report the usefulness of pressure-sensitive adhesive tape containing bleomycin sulfate for common and plantar warts.Acrylic adhesive was casted on a nonwoven fabric laminated polyurethane film as a backing. The adhesive surface of the tape was coated evenly with a solution containing bleomycin sulfate (5.3 mg/mL in ethanol and water [9:1]) and dried at room temperature. The final content of bleomycin sulfate was 60 μg/sq cm of the tape, as assessed by high-performance liquid chromatography. Placebo tape did not contain bleomycin sulfate.Seven patients with common warts and two with plantar warts were selected to participate in our study. They had not been treated previously for warts. Bleomycin References 1. Nagington J, Rook A: Virus and related infection , in Rook A, Wilkinson DS, Ebling FJG (eds): Textbook of Dermatology , ed 3. Oxford, England, Blackwell Scientific Publications, 1979, pp 618-627. 2. Shumer SM, O'Keefe EJ: Bleomycin in the treatment of recalcitrant warts . J Am Acad Dermatol 1983;9:91-96.Crossref 3. Yagoda A, Mukherji B, Young C, et al: Bleomycin, an antitumor antibiotic: Clinical experience in 274 patients . Ann Intern Med 1972;77:861-870.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Treatment of Viral Warts With Pressure-Sensitive Adhesive Tape Containing Bleomycin Sulfate

Treatment of Viral Warts With Pressure-Sensitive Adhesive Tape Containing Bleomycin Sulfate

Abstract

Abstract To the Editor.— The currently employed manipulations for the treatment of common and plantar warts depend mainly on physical and chemical destruction of the warts.1,2 One of the disadvantages in these maneuvers is associated pain at the treated site. Herein, we report the usefulness of pressure-sensitive adhesive tape containing bleomycin sulfate for common and plantar warts.Acrylic adhesive was casted on a nonwoven fabric laminated polyurethane film as a backing. The adhesive...
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Publisher
American Medical Association
Copyright
Copyright © 1985 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1985.01660090022008
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor.— The currently employed manipulations for the treatment of common and plantar warts depend mainly on physical and chemical destruction of the warts.1,2 One of the disadvantages in these maneuvers is associated pain at the treated site. Herein, we report the usefulness of pressure-sensitive adhesive tape containing bleomycin sulfate for common and plantar warts.Acrylic adhesive was casted on a nonwoven fabric laminated polyurethane film as a backing. The adhesive surface of the tape was coated evenly with a solution containing bleomycin sulfate (5.3 mg/mL in ethanol and water [9:1]) and dried at room temperature. The final content of bleomycin sulfate was 60 μg/sq cm of the tape, as assessed by high-performance liquid chromatography. Placebo tape did not contain bleomycin sulfate.Seven patients with common warts and two with plantar warts were selected to participate in our study. They had not been treated previously for warts. Bleomycin References 1. Nagington J, Rook A: Virus and related infection , in Rook A, Wilkinson DS, Ebling FJG (eds): Textbook of Dermatology , ed 3. Oxford, England, Blackwell Scientific Publications, 1979, pp 618-627. 2. Shumer SM, O'Keefe EJ: Bleomycin in the treatment of recalcitrant warts . J Am Acad Dermatol 1983;9:91-96.Crossref 3. Yagoda A, Mukherji B, Young C, et al: Bleomycin, an antitumor antibiotic: Clinical experience in 274 patients . Ann Intern Med 1972;77:861-870.Crossref

Journal

Archives of DermatologyAmerican Medical Association

Published: Sep 1, 1985

References