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TREATMENT OF TRICHOMONAS VAGINITIS WITH CONCENTRATED SALT SOLUTION

TREATMENT OF TRICHOMONAS VAGINITIS WITH CONCENTRATED SALT SOLUTION Abstract At present, various chemical agents are being applied in order to destroy Trichomonas vaginalis. However, chemotherapy is frequently unsatisfactory for the following reasons: 1. In order to be effective, many chemicals must be used in concentrations that may be harmful to the vaginal mucosa, especially during prolonged treatment. 2. There is always a possibility that in the course of treatment a strain of the parasite may develop that is resistant to the chemotherapeutic agent. 3. Most of the chemotherapeutic methods are relatively complicated and cannot be applied by the patient at her home. Taking into consideration the fact that protozoa in general are sensitive to variations in osmotic pressure of the surrounding medium, it occurred to us that the vaginal protozoon may also be affected by such variations. We therefore decided to study the action of hypertonic salt solutions on Trichomonas vaginalis. The fact that Trichomonas vaginalis is an extra-cellular References 1. Schewiakoff, W.: Scheintod und Wiederbelebung sowie andere Schutzbildungen bei Marinen Infusorien , Publ. della Staz. Zoolog. Napoli 9: 59, 1928. 2. Davis, C. H.: Leukorrhea , in Curtis, H. H.: Obstetrics and Gynecology , Philadelphia, W. B. Saunders Company 3:439, 1933. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

TREATMENT OF TRICHOMONAS VAGINITIS WITH CONCENTRATED SALT SOLUTION

JAMA , Volume 105 (2) – Jul 13, 1935

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References (3)

Publisher
American Medical Association
Copyright
Copyright © 1935 American Medical Association. All Rights Reserved.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1935.02760280017005
Publisher site
See Article on Publisher Site

Abstract

Abstract At present, various chemical agents are being applied in order to destroy Trichomonas vaginalis. However, chemotherapy is frequently unsatisfactory for the following reasons: 1. In order to be effective, many chemicals must be used in concentrations that may be harmful to the vaginal mucosa, especially during prolonged treatment. 2. There is always a possibility that in the course of treatment a strain of the parasite may develop that is resistant to the chemotherapeutic agent. 3. Most of the chemotherapeutic methods are relatively complicated and cannot be applied by the patient at her home. Taking into consideration the fact that protozoa in general are sensitive to variations in osmotic pressure of the surrounding medium, it occurred to us that the vaginal protozoon may also be affected by such variations. We therefore decided to study the action of hypertonic salt solutions on Trichomonas vaginalis. The fact that Trichomonas vaginalis is an extra-cellular References 1. Schewiakoff, W.: Scheintod und Wiederbelebung sowie andere Schutzbildungen bei Marinen Infusorien , Publ. della Staz. Zoolog. Napoli 9: 59, 1928. 2. Davis, C. H.: Leukorrhea , in Curtis, H. H.: Obstetrics and Gynecology , Philadelphia, W. B. Saunders Company 3:439, 1933.

Journal

JAMAAmerican Medical Association

Published: Jul 13, 1935

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