Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

TREATMENT OF PYOGENIC DERMATOSES WITH TOPICAL CHLORAMPHENICOL (CHLOROMYCETIN®)

TREATMENT OF PYOGENIC DERMATOSES WITH TOPICAL CHLORAMPHENICOL (CHLOROMYCETIN®) Abstract The list of topical antibacterial preparations used for the treatment of pyogenic infections of the skin continues to grow. Some of the most effective topical agents in common use are ammoniated mercury, chlorhydroxyquinoline, iodochlorohydroxyquinoline (vioform®), nitrofurazone (furacin®) acriflavine, sulfonamides, penicillin, bacitracin, and aureomycin. The aim has been toward the development of topical agents which would be effective against a wide range of micro-organisms and at the same time have a low index of sensitivity. The sulfonamides and penicillin have fallen into disrepute because of the high incidence of sensitization seen following their use. Miller and co-workers 1 state that in early use penicillin sensitized 6% of patients; sulfonamides, 5%, and nitrofurazone, 5%. The newer antibiotics, such as bacitracin and aureomycin, incorporated into ointment form appear to be approaching more nearly the ideal type of topical antibacterial medication because of their apparent low index of sensitivity as well as their effectiveness. References 1. Miller, J. L.; Slatkin, M. H., and Johnson, B. A.: Evaluation of Bacitracin in Local Treatment of Pyogenic Infections , Arch. Dermat. & Syph. 60:106-120 ( (July) ) 1949. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Dermatology & Syphilology American Medical Association

TREATMENT OF PYOGENIC DERMATOSES WITH TOPICAL CHLORAMPHENICOL (CHLOROMYCETIN®)

Loading next page...
 
/lp/american-medical-association/treatment-of-pyogenic-dermatoses-with-topical-chloramphenicol-KL90VY689e
Publisher
American Medical Association
Copyright
Copyright © 1951 American Medical Association. All Rights Reserved.
ISSN
0096-5979
DOI
10.1001/archderm.1951.01570080096022
Publisher site
See Article on Publisher Site

Abstract

Abstract The list of topical antibacterial preparations used for the treatment of pyogenic infections of the skin continues to grow. Some of the most effective topical agents in common use are ammoniated mercury, chlorhydroxyquinoline, iodochlorohydroxyquinoline (vioform®), nitrofurazone (furacin®) acriflavine, sulfonamides, penicillin, bacitracin, and aureomycin. The aim has been toward the development of topical agents which would be effective against a wide range of micro-organisms and at the same time have a low index of sensitivity. The sulfonamides and penicillin have fallen into disrepute because of the high incidence of sensitization seen following their use. Miller and co-workers 1 state that in early use penicillin sensitized 6% of patients; sulfonamides, 5%, and nitrofurazone, 5%. The newer antibiotics, such as bacitracin and aureomycin, incorporated into ointment form appear to be approaching more nearly the ideal type of topical antibacterial medication because of their apparent low index of sensitivity as well as their effectiveness. References 1. Miller, J. L.; Slatkin, M. H., and Johnson, B. A.: Evaluation of Bacitracin in Local Treatment of Pyogenic Infections , Arch. Dermat. & Syph. 60:106-120 ( (July) ) 1949.

Journal

A.M.A. Archives of Dermatology & SyphilologyAmerican Medical Association

Published: Aug 1, 1951

References