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References (15)
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E. Marshall, P. Long (1939)
THE INTRAVENOUS USE OF SODIUM SULFAPYRIDINEJAMA, 112
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H. Hodes, W. Stifler, E. Walker, M. Mccarty, R. Shirley (1939)
The use of sulfapyridine in primary pneumococcic pneumonia and in pneumococcic pneumonia associated with measlesThe Journal of Pediatrics, 14
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H. Barnett, A. Hartmann, A. Perley, Mary Ruhoff (1939)
THE TREATMENT OF PNEUMOCOCCIC INFECTIONS IN INFANTS AND CHILDREN WITH SULFAPYRIDINEJAMA, 112
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ACQUIRED TOLERANCE OF PNEUMOCOCCUS TO M. & B. 693The Lancet, 233
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H. Flippin, J. Lockwood, D. Pepper, L. Schwartz (1939)
THE TREATMENT OF PNEUMOCOCCIC PNEUMONIA WITH SULFAPYRIDINE: A PROGRESS REPORT ON OBSERVATIONS IN 100 CASESJAMA, 112
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L. Whitby (1938)
CHEMOTHERAPY OF PNEUMOCOCCAL AND OTHER INFECTIONS: WITH 2-(p-AMINOBENZENESULPHONAMIDO) PYRIDINEThe Lancet, 231
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E. Marshall, A. Bratton, J. Litchfield (1938)
THE TOXICITY AND ABSORPTION OF 2-SULFANILAMIDOPYRIDINE AND ITS SOLUBLE SODIUM SALT.Science, 88 2295
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PNEUMOCOCCAL MENINGITIS TREATED WITH M. & B. 693The Lancet, 233
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THE TREATMENT OF PNEUMOCOCCIC PNEUMONIA WITH SULFAPYRIDINE.Canadian Medical Association journal, 40 4
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PNEUMOCOCCAL MENINGITIS TREATED WITH M. & B. 693: RECOVERYThe Lancet, 232
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SULFAPYRIDINE IN PNEUMONIAJAMA, 112
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W. MacColl (1939)
Clinical experience with sulfapyridineThe Journal of Pediatrics, 14
- Publisher
- American Medical Association
- Copyright
- Copyright © 1939 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
- ISSN
- 0098-7484
- eISSN
- 1538-3598
- DOI
- 10.1001/jama.1939.02800430006002
- Publisher site
- See Article on Publisher Site
Abstract
Since the demonstration by Whitby1 of the effectiveness of sulfapyridine against pneumococcic infections in mice, many clinical reports have shown that the drug is of definite value in the treatment of pneumonia in man. It appears that the mortality rate from pneumonia in both children and adults is reduced when sulfapyridine is used.2 Reports have appeared which indicate that the drug may be of value also in pneumococcic meningitis.3 However, the number of cases thus far described is so small that one cannot be certain that the prognosis in this disease will be, in general, altered by the use of sulfapyridine. There are published in the literature the records of only fourteen patients with pneumococcic meningitis who were treated with sulfapyridine alone. Eight of the fourteen recovered. The present communication deals with the use of sulfapyridine and its sodium salt4 in the treatment of seventeen patients with pneumococcic meningitis admitted to the Sydenham Hospital between October 1938 and May 1939. Eight of these seventeen (47 per cent) recovered completely. Antipneumococcic serum
Journal
JAMA – American Medical Association
Published: Oct 28, 1939