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TREATMENT OF NEUROSYPHILIS BY MALARIA: FURTHER OBSERVATIONS

TREATMENT OF NEUROSYPHILIS BY MALARIA: FURTHER OBSERVATIONS Abstract In May, 1925, we reported the first year's observation of thirty-five cases of neurosyphilis treated with malaria,1 as suggested by Wagner von Jauregg.2 At that time we did not draw conclusions but attempted only to report our brief experience with the method. Some of the patients had shown such definite improvement one or two months after the course of malaria that a summary of the results was included, but we made no effort to interpret their significance. We felt that conclusions should be drawn only after treating a larger series of patients and observing them for several years. In this paper we shall report the second year's observations on the original thirty-five patients treated (first group) and add sixty-five additional cases (second group) in which treatment has been given during the year just past. The bulk of this report will be the result of the continued observations on References 1. O'Leary, P. A.; Goeckerman, W. H., and Parker, S. T.: Treatment of Neurosyphilis by Malaria: A Preliminary Report , Arch. Dermat. & Syph. 13: 301-320 ( (March) ) 1926. 2. Wagner von Jauregg, Julius: Ueber die Einwirkung fieberhafter Erkrankungen auf Psychosen , Jahrb. f. Psychiat. 7:94-131, 1887 3. Ueber die Behandlung der progressiven Paralyse , Wien. med. Wchnschr. 59:2124-2127, 1909 4. Ueber die Einwirkung der Malaria auf die progressive Paralyse , Psychiat.-neurol. Wchnschr. 20:132 and 251, 1918-1919 5. Ikhtemann, M.: Rosenblum's Priority for Malaria Treatment of General Paralysis , Ann. d. mal. vén. 20:561-565, 1925 6. O'Leary, P. A., and Becker, S. W.: Further Observations on the Treatment of Neurosyphilis with Tryparsamide , M. J. & Record 123:305-308, 1926. 7. Purves-Stewart, James: The Treatment of General Paralysis , Brit. M. J. 1:508-510, 1924. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology and Syphilology American Medical Association

TREATMENT OF NEUROSYPHILIS BY MALARIA: FURTHER OBSERVATIONS

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Publisher
American Medical Association
Copyright
Copyright © 1926 American Medical Association. All Rights Reserved.
ISSN
0096-6029
DOI
10.1001/archderm.1926.02370230051005
Publisher site
See Article on Publisher Site

Abstract

Abstract In May, 1925, we reported the first year's observation of thirty-five cases of neurosyphilis treated with malaria,1 as suggested by Wagner von Jauregg.2 At that time we did not draw conclusions but attempted only to report our brief experience with the method. Some of the patients had shown such definite improvement one or two months after the course of malaria that a summary of the results was included, but we made no effort to interpret their significance. We felt that conclusions should be drawn only after treating a larger series of patients and observing them for several years. In this paper we shall report the second year's observations on the original thirty-five patients treated (first group) and add sixty-five additional cases (second group) in which treatment has been given during the year just past. The bulk of this report will be the result of the continued observations on References 1. O'Leary, P. A.; Goeckerman, W. H., and Parker, S. T.: Treatment of Neurosyphilis by Malaria: A Preliminary Report , Arch. Dermat. & Syph. 13: 301-320 ( (March) ) 1926. 2. Wagner von Jauregg, Julius: Ueber die Einwirkung fieberhafter Erkrankungen auf Psychosen , Jahrb. f. Psychiat. 7:94-131, 1887 3. Ueber die Behandlung der progressiven Paralyse , Wien. med. Wchnschr. 59:2124-2127, 1909 4. Ueber die Einwirkung der Malaria auf die progressive Paralyse , Psychiat.-neurol. Wchnschr. 20:132 and 251, 1918-1919 5. Ikhtemann, M.: Rosenblum's Priority for Malaria Treatment of General Paralysis , Ann. d. mal. vén. 20:561-565, 1925 6. O'Leary, P. A., and Becker, S. W.: Further Observations on the Treatment of Neurosyphilis with Tryparsamide , M. J. & Record 123:305-308, 1926. 7. Purves-Stewart, James: The Treatment of General Paralysis , Brit. M. J. 1:508-510, 1924.

Journal

Archives of Dermatology and Syphilology – American Medical Association

Published: Nov 1, 1926

References

  • Treatment of Neurosyphilis by Malaria: A Preliminary Report
    O'Leary , P. A.; Goeckerman, W. H., and Parker, S. T.
  • Ueber die Einwirkung fieberhafter Erkrankungen auf Psychosen
    Wagner von Jauregg , Julius
  • Ueber die Behandlung der progressiven Paralyse
  • Ueber die Einwirkung der Malaria auf die progressive Paralyse
  • Rosenblum's Priority for Malaria Treatment of General Paralysis
    Ikhtemann , M.
  • Further Observations on the Treatment of Neurosyphilis with Tryparsamide
    O'Leary , P. A., and Becker, S. W.
  • The Treatment of General Paralysis
    Purves-Stewart , James