Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You and Your Team.

Learn More →

TREATMENT OF JUVENILE PAPILLOMA OF THE LARYNX WITH RESIN OF PODOPHYLLUM: A Preliminary Report

TREATMENT OF JUVENILE PAPILLOMA OF THE LARYNX WITH RESIN OF PODOPHYLLUM: A Preliminary Report Abstract PAPILLOMA of the larynx in children is an extremely distressing disorder. Obstructive symptoms and the resulting severe infections of the respiratory tract frequently increase in spite of continuous care. Ferguson and Scott1 reviewed 15 of their cases from 1933 to 1942 in which death resulted from asphyxia in 2 and laryngeal diphtheria developed with ensuing death in 1. A great variety of treatments, including irradiation and hormone therapy, have been tried without consistent good results.2 The disorder has been considered to be self limited, with recurrences, and eventually to cease. Many have reached the conclusion that the only therapy indicated is insurance of adequate airway by repeated removal of the lesions and tracheotomy if necessary.3 Long hospitalization and repeated instrumentation are necessary with this therapy. Extension or implantation of the papilloma low in the trachea with ensuing obstruction is a serious problem and cause of great frustration to the one References 1. Ferguson, C. F., and Scott, H. W.: Papillomatosis of the Larynx in Childhood , New England J. Med. 230:477-482 ( (April) ) 1944.Crossref 2. New, G. B.: Treatment of Multiple Papillomas of Larynx in Children , Ann. Otol., Rhin. & Laryng. 30:631-636 ( (Sept.) ) 1921. 3. Foster, J. H.: Papillomatosis Laryngis , Ann. Otol., Rhin. & Laryng. 42:548-559 ( (June) ) 1933. 4. Broyles, E. N.: Treatment of Laryngeal Papilloma in Children with Estrogenic Hormones: Preliminary Report , Bull. Johns Hopkins Hosp. 55:319-322 ( (May) ) 1940. 5. Jackson, C., and Jackson, C. L.: Diseases and Injuries of the Larynx , ed. 2, New York, The Macmillan Company, 1942. 6. Eggston, A. A., and Wolff, D.: Histopathology of the Ear, Nose and Throat , Baltimore, Williams & Wilkins Company, 1947. 7. Kaplan, I. W.: Condylomata Acuminata , New Orleans M. & S. J. 94:388-390 ( (Feb.) ) 1942. 8. Sullivan, M.: Treatment of Cutaneous Carcinoma with Podophyllin , Bull. Johns Hopkins Hosp. 85:200-203 ( (Sept.) ) 1949. 9. King, L. S., and Sullivan, M.: Effects of Podophyllin and of Colchicine on Normal Skin, on Condyloma Acuminatum and on Verruca Vulgaris , Arch. Path. 43:374-386 ( (April) ) 1947. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngology American Medical Association

TREATMENT OF JUVENILE PAPILLOMA OF THE LARYNX WITH RESIN OF PODOPHYLLUM: A Preliminary Report

Loading next page...
 
/lp/american-medical-association/treatment-of-juvenile-papilloma-of-the-larynx-with-resin-of-PwkQTw0NgQ
Publisher
American Medical Association
Copyright
Copyright © 1950 American Medical Association. All Rights Reserved.
ISSN
0003-9977
DOI
10.1001/archotol.1950.00700030101011
Publisher site
See Article on Publisher Site

Abstract

Abstract PAPILLOMA of the larynx in children is an extremely distressing disorder. Obstructive symptoms and the resulting severe infections of the respiratory tract frequently increase in spite of continuous care. Ferguson and Scott1 reviewed 15 of their cases from 1933 to 1942 in which death resulted from asphyxia in 2 and laryngeal diphtheria developed with ensuing death in 1. A great variety of treatments, including irradiation and hormone therapy, have been tried without consistent good results.2 The disorder has been considered to be self limited, with recurrences, and eventually to cease. Many have reached the conclusion that the only therapy indicated is insurance of adequate airway by repeated removal of the lesions and tracheotomy if necessary.3 Long hospitalization and repeated instrumentation are necessary with this therapy. Extension or implantation of the papilloma low in the trachea with ensuing obstruction is a serious problem and cause of great frustration to the one References 1. Ferguson, C. F., and Scott, H. W.: Papillomatosis of the Larynx in Childhood , New England J. Med. 230:477-482 ( (April) ) 1944.Crossref 2. New, G. B.: Treatment of Multiple Papillomas of Larynx in Children , Ann. Otol., Rhin. & Laryng. 30:631-636 ( (Sept.) ) 1921. 3. Foster, J. H.: Papillomatosis Laryngis , Ann. Otol., Rhin. & Laryng. 42:548-559 ( (June) ) 1933. 4. Broyles, E. N.: Treatment of Laryngeal Papilloma in Children with Estrogenic Hormones: Preliminary Report , Bull. Johns Hopkins Hosp. 55:319-322 ( (May) ) 1940. 5. Jackson, C., and Jackson, C. L.: Diseases and Injuries of the Larynx , ed. 2, New York, The Macmillan Company, 1942. 6. Eggston, A. A., and Wolff, D.: Histopathology of the Ear, Nose and Throat , Baltimore, Williams & Wilkins Company, 1947. 7. Kaplan, I. W.: Condylomata Acuminata , New Orleans M. & S. J. 94:388-390 ( (Feb.) ) 1942. 8. Sullivan, M.: Treatment of Cutaneous Carcinoma with Podophyllin , Bull. Johns Hopkins Hosp. 85:200-203 ( (Sept.) ) 1949. 9. King, L. S., and Sullivan, M.: Effects of Podophyllin and of Colchicine on Normal Skin, on Condyloma Acuminatum and on Verruca Vulgaris , Arch. Path. 43:374-386 ( (April) ) 1947.

Journal

Archives of OtolaryngologyAmerican Medical Association

Published: Jul 1, 1950

References