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Treatment of Hirschsprung's Disease with Entire Colon Involved in Aganglionic Defect

Treatment of Hirschsprung's Disease with Entire Colon Involved in Aganglionic Defect Abstract In our experience with 150 patients having Hirschsprung's disease, 2 patients have been encountered in whom the entire colon was deficient in ganglion cells. Diagnosis and treatment of this condition required variations from that followed in the usual cases of Hirschsprung's disease where the aganglionic segment is limited to the rectum and rectosigmoid. The two patients with deficient Auerbach's plexus ganglion cells throughout the colon presented so bizarre a clinical picture in comparison with that typically encountered in congenital megacolon, that they posed a considerable diagnostic problem. Both of these infants were admitted to the hospital because of abdominal distention and vomiting. Roentgenograms with barium revealed the colon to be essentially normal in size, the abdominal distention being due to small bowel dilatation. There was some attempt to empty the colon; however, a portion of the barium was retained in the colon and was still there in one patient several References 1. References 1 to 5. 2. Bruening, F.: Zur Ätiologie und Therapie der Hirschsprungschen Krankheit , Arch. klin, Chir. 138:453-448, 1925. 3. Junghanns, H.: Volkommene Dickdarmentfernung bei Hirschsprungschen Krankheit , Deutsche Ztschr. Chir. 257:609-620, 1943.Crossref 4. Grimson, K. S.; Vandegrift, H. N., and Dratz, H. M.: Surgery in Obstinate Megacolon: Radical One Stage Resection and Ileosigmoidostomy , Surg., Gynec. & Obst. 80:164-173, 1945. 5. d'Allaines, F.: Colectomie totale pour megacolon , Mém. Acad. chir. 73:246-249, 1947. 6. Hepp, J., and Petit, P.: Colectomie totale pour maladie de Hirschsprung après échec d'une double sympathectomie lombaire et d'une hémicolectomie gauche , Arch. mal. app. digest. 36:387-392, 1947. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives Surgery American Medical Association

Treatment of Hirschsprung's Disease with Entire Colon Involved in Aganglionic Defect

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Publisher
American Medical Association
Copyright
Copyright © 1955 American Medical Association. All Rights Reserved.
ISSN
0096-6908
DOI
10.1001/archsurg.1955.01270100061010
Publisher site
See Article on Publisher Site

Abstract

Abstract In our experience with 150 patients having Hirschsprung's disease, 2 patients have been encountered in whom the entire colon was deficient in ganglion cells. Diagnosis and treatment of this condition required variations from that followed in the usual cases of Hirschsprung's disease where the aganglionic segment is limited to the rectum and rectosigmoid. The two patients with deficient Auerbach's plexus ganglion cells throughout the colon presented so bizarre a clinical picture in comparison with that typically encountered in congenital megacolon, that they posed a considerable diagnostic problem. Both of these infants were admitted to the hospital because of abdominal distention and vomiting. Roentgenograms with barium revealed the colon to be essentially normal in size, the abdominal distention being due to small bowel dilatation. There was some attempt to empty the colon; however, a portion of the barium was retained in the colon and was still there in one patient several References 1. References 1 to 5. 2. Bruening, F.: Zur Ätiologie und Therapie der Hirschsprungschen Krankheit , Arch. klin, Chir. 138:453-448, 1925. 3. Junghanns, H.: Volkommene Dickdarmentfernung bei Hirschsprungschen Krankheit , Deutsche Ztschr. Chir. 257:609-620, 1943.Crossref 4. Grimson, K. S.; Vandegrift, H. N., and Dratz, H. M.: Surgery in Obstinate Megacolon: Radical One Stage Resection and Ileosigmoidostomy , Surg., Gynec. & Obst. 80:164-173, 1945. 5. d'Allaines, F.: Colectomie totale pour megacolon , Mém. Acad. chir. 73:246-249, 1947. 6. Hepp, J., and Petit, P.: Colectomie totale pour maladie de Hirschsprung après échec d'une double sympathectomie lombaire et d'une hémicolectomie gauche , Arch. mal. app. digest. 36:387-392, 1947.

Journal

A.M.A. Archives Surgery – American Medical Association

Published: Apr 1, 1955

References

  • Zur Ätiologie und Therapie der Hirschsprungschen Krankheit
    Bruening , F.
  • Volkommene Dickdarmentfernung bei Hirschsprungschen Krankheit
    Junghanns , H.
  • Surgery in Obstinate Megacolon: Radical One Stage Resection and Ileosigmoidostomy
    Grimson , K. S.; Vandegrift, H. N., and Dratz, H. M.
  • Colectomie totale pour megacolon
    d'Allaines , F.
  • Colectomie totale pour maladie de Hirschsprung après échec d'une double sympathectomie lombaire et d'une hémicolectomie gauche
    Hepp , J., and Petit, P.