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Treatment of Herpes Simplex Keratitis with Copper Sulfate Iontophoresis: A Preliminary Report

Treatment of Herpes Simplex Keratitis with Copper Sulfate Iontophoresis: A Preliminary Report Abstract At present there is no completely satisfactory treatment for herpes simplex keratitis, as evidenced by the high incidence of recurrences, the stromal scarring from repeated attacks and repeated cauterization treatments, and the prolonged course of the stromal forms of the disease. Because of this, various methods of treatment are being studied, and the purpose of this paper is to present a preliminary report of the results of copper sulfate iontophoresis treatment of herpes simplex keratitis. Materials Twenty patients with various forms of herpes simplex keratitis were treated, of which there were 9 eyes with dendritic ulcers; 8 eyes with acute or chronic ulcers and stromal involvement; 2 eyes with reactivation of deep stromal as well as epithelial keratitis; and 1 eye with disciform keratitis. Steroid preparations had been used by 5 of the patients prior to their first visit; 4 topically and 1 systemically as well as topically. Method The References 1. Goodman, L. S., and Gillman, A.: Pharmacological Basis of Therapeutics , New York, The MacMillan Commpany, 1955, p. 1108. 2. Byers, J.; Holland, M. G., and Allen, J. H.: Cephalosporium Keratitis , Amer. J. Ophthal. 49:267, 1960. 3. Ferron,: Chemotherapy of the Herpetic Diseases in Ophthalmology , Arch. Soc. Oftal. Hisp.-Amer. 12:1106, 1952. 4. Sery, T. W., and Furgiuele, F. P.: Inactivation of Herpes Simplex Virus by Chemical Agents , Amer. J. Ophthal. 51:42, 1961. 5. Erlanger, G.: Iontophoresis: A Scientific and Practical Tool in Ophthalmology , Ophthalmologica , 128:232, 1954.Crossref 6. Gundersen, T.: Herpes Corneae , Arch. Ophthal. 15:225, 1936.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Treatment of Herpes Simplex Keratitis with Copper Sulfate Iontophoresis: A Preliminary Report

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Publisher
American Medical Association
Copyright
Copyright © 1962 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1962.00960020453011
Publisher site
See Article on Publisher Site

Abstract

Abstract At present there is no completely satisfactory treatment for herpes simplex keratitis, as evidenced by the high incidence of recurrences, the stromal scarring from repeated attacks and repeated cauterization treatments, and the prolonged course of the stromal forms of the disease. Because of this, various methods of treatment are being studied, and the purpose of this paper is to present a preliminary report of the results of copper sulfate iontophoresis treatment of herpes simplex keratitis. Materials Twenty patients with various forms of herpes simplex keratitis were treated, of which there were 9 eyes with dendritic ulcers; 8 eyes with acute or chronic ulcers and stromal involvement; 2 eyes with reactivation of deep stromal as well as epithelial keratitis; and 1 eye with disciform keratitis. Steroid preparations had been used by 5 of the patients prior to their first visit; 4 topically and 1 systemically as well as topically. Method The References 1. Goodman, L. S., and Gillman, A.: Pharmacological Basis of Therapeutics , New York, The MacMillan Commpany, 1955, p. 1108. 2. Byers, J.; Holland, M. G., and Allen, J. H.: Cephalosporium Keratitis , Amer. J. Ophthal. 49:267, 1960. 3. Ferron,: Chemotherapy of the Herpetic Diseases in Ophthalmology , Arch. Soc. Oftal. Hisp.-Amer. 12:1106, 1952. 4. Sery, T. W., and Furgiuele, F. P.: Inactivation of Herpes Simplex Virus by Chemical Agents , Amer. J. Ophthal. 51:42, 1961. 5. Erlanger, G.: Iontophoresis: A Scientific and Practical Tool in Ophthalmology , Ophthalmologica , 128:232, 1954.Crossref 6. Gundersen, T.: Herpes Corneae , Arch. Ophthal. 15:225, 1936.Crossref

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Apr 1, 1962

References