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Treatment of Eczema Herpeticum with Gamma Globulin

Treatment of Eczema Herpeticum with Gamma Globulin Abstract Eczema herpeticum was first described in classical fashion by Kaposi1 in 1887. It is characterized by poorly grouped, umbilicated, vesicular lesions containing clear serum, which occur initially on the eczematous skin. The onset is very acute, accompanied by high fever and malaise, and other lesions may appear later on the noneczematous areas. As early as 1898 Juliusberg2 suggested that a virus might be the etiological agent because the lesions resembled vaccination pustules. However, for many years confusion existed because the term Kaposi's varicelliform eruption included both those eruptions resulting from a herpes simplex infection and those of the vaccinia virus. In 1941 Esser3 and Seidenberg4 isolated the virus of herpes simplex from cases of Kaposi's varicelliform eruption, and the suggestion of Juliusberg was verified. After this the two diseases came to be differentiated, with the eruption caused by the virus References 1. Kaposi, M.: Pathologie und therapie der Hautkrankheiten , in Vorlesungen für praktische Aerzte und Studirende , Vienna, Urban & Schwarzenberg: 1887, p. 483. 2. Juliusberg, F.: Über Pustulosis acuta varioliformis , Arch. Dermat. u. Syph. 46:21, 1898.Crossref 3. Esser, M.: Über eine kleine Epidemie von Pustulosis varioliformis acuta , Anna. pædiat. 157:156, 1941. 4. Seidenberg, S.: Zur Ätiologie der Pustulosis vacciniformis acuta , Schweiz. Ztschr. Path. u. Bakt. 4:398, 1941. 5. Lynch, F. W.; Evans, C. A.; Bolin, V. S., and Steves, R. J.: Kaposi's Varicelliform Eruption: Extensive Herpes Simplex as a Complication of Eczema , Arch. Dermat. & Syph. 51:129, 1945. 6. Barker, L. P., and Hallinger, E. S., Jr.: Systemic Herpes Simplex (Kaposi's Varicelliform Eruption) , J. A. M. A. 135:149, 1947. 7. Sulzberger, M. B., and Baer, R.: Editorial Comment, in The 1947 Year Book of Dermatology and Syphilology , Chicago, The Year Book Publishers, Inc., 1948, p. 345. 8. Barrow, G. I.: The Herpes Simplex Virus in Infantile Eczema , Brit. M. J. 1:482, 1954. 9. Ruchman, I.; Welsh, A. L., and Dodd, K.: Kaposi's Varicelliform Eruption: Isolation of the Virus of Herpes Simplex from the Cutaneous Lesions of Three Adults and One Infant , Arch. Dermat. & Syph. 56:846, 1947. 10. Brain, R. T.: The Clinical Varices of the Herpes Virus , Brit. M. J. 1:1061, 1956. 11. Ormsby, O. S., and Montgomery, H.: Diseases of the Skin , Ed. 8, Philadelphia, Lea & Febiger, 1954, 507. 12. O'Leary, P. A.: in discussion on Lane, C. W., and Herold, W. C.: Kaposi's Varicelliform Eruption , Arch. Dermat. & Syph. 50:396, 1944. 13. Lynch, F. W., and Steves, R. J.: Kaposi's Varicelliform Eruption , Arch. Dermat. & Syph. 55:327, 1947. 14. Blattner, R. J.; Heys, F. M., and Harrison, M. L. K.: Etiology of Kaposi's Varicelliform Eruption , J. Pediat. 27:207, 1945. 15. Blank, H., and Rake, G.: Viral and Rickettsial Diseases of the Skin, Eye, and Mucous Membranes in Viral and Rickettsial Infections of Man , Edited by T. M. Rivers, Ed. 2, Philadelphia, J. B. Lippincott Company, 1952, p. 54. 16. Buret, F., and Lush, D.: Herpes Simplex: Studies of the Antibody Content of Human Sera , Lancet 1:629, 1939. 17. Enders, J. F.: Clinical and Immunological Studies on the Products of Plasma Fractionation , J. Clin. Invest. 23:510, 1944. 18. Miller, O. B.; Arbesman, C., and Baer, R.: Disseminated Cutaneous Herpes Simplex, (Kaposi's Varicelliform Eruption) , Arch. Dermat. & Syph. 62:477, 1950. 19. Weintraub, I. I.: Treatment of Herpes Zoster with Gamma Globulin , J. A. M. A. 157:1611, 1955. 20. Rodarte, J. G., and Williams, B. H.: Treatment of Herpes Zoster and Chicken Pox with Immune Globulin , Arch. Dermat. & Syph. 73:553, 1956. 21. Fox, M. J., and Pica, V. B.: Treatment of Eczema Vaccinatum by Specific Gamma Globulin: A Case Report , Wisconsin M. J. 55:972, 1956. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Dermatology American Medical Association

Treatment of Eczema Herpeticum with Gamma Globulin

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Publisher
American Medical Association
Copyright
Copyright © 1957 American Medical Association. All Rights Reserved.
ISSN
0096-5359
DOI
10.1001/archderm.1957.01550230038006
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Abstract

Abstract Eczema herpeticum was first described in classical fashion by Kaposi1 in 1887. It is characterized by poorly grouped, umbilicated, vesicular lesions containing clear serum, which occur initially on the eczematous skin. The onset is very acute, accompanied by high fever and malaise, and other lesions may appear later on the noneczematous areas. As early as 1898 Juliusberg2 suggested that a virus might be the etiological agent because the lesions resembled vaccination pustules. However, for many years confusion existed because the term Kaposi's varicelliform eruption included both those eruptions resulting from a herpes simplex infection and those of the vaccinia virus. In 1941 Esser3 and Seidenberg4 isolated the virus of herpes simplex from cases of Kaposi's varicelliform eruption, and the suggestion of Juliusberg was verified. After this the two diseases came to be differentiated, with the eruption caused by the virus References 1. Kaposi, M.: Pathologie und therapie der Hautkrankheiten , in Vorlesungen für praktische Aerzte und Studirende , Vienna, Urban & Schwarzenberg: 1887, p. 483. 2. Juliusberg, F.: Über Pustulosis acuta varioliformis , Arch. Dermat. u. Syph. 46:21, 1898.Crossref 3. Esser, M.: Über eine kleine Epidemie von Pustulosis varioliformis acuta , Anna. pædiat. 157:156, 1941. 4. Seidenberg, S.: Zur Ätiologie der Pustulosis vacciniformis acuta , Schweiz. Ztschr. Path. u. Bakt. 4:398, 1941. 5. Lynch, F. W.; Evans, C. A.; Bolin, V. S., and Steves, R. J.: Kaposi's Varicelliform Eruption: Extensive Herpes Simplex as a Complication of Eczema , Arch. Dermat. & Syph. 51:129, 1945. 6. Barker, L. P., and Hallinger, E. S., Jr.: Systemic Herpes Simplex (Kaposi's Varicelliform Eruption) , J. A. M. A. 135:149, 1947. 7. Sulzberger, M. B., and Baer, R.: Editorial Comment, in The 1947 Year Book of Dermatology and Syphilology , Chicago, The Year Book Publishers, Inc., 1948, p. 345. 8. Barrow, G. I.: The Herpes Simplex Virus in Infantile Eczema , Brit. M. J. 1:482, 1954. 9. Ruchman, I.; Welsh, A. L., and Dodd, K.: Kaposi's Varicelliform Eruption: Isolation of the Virus of Herpes Simplex from the Cutaneous Lesions of Three Adults and One Infant , Arch. Dermat. & Syph. 56:846, 1947. 10. Brain, R. T.: The Clinical Varices of the Herpes Virus , Brit. M. J. 1:1061, 1956. 11. Ormsby, O. S., and Montgomery, H.: Diseases of the Skin , Ed. 8, Philadelphia, Lea & Febiger, 1954, 507. 12. O'Leary, P. A.: in discussion on Lane, C. W., and Herold, W. C.: Kaposi's Varicelliform Eruption , Arch. Dermat. & Syph. 50:396, 1944. 13. Lynch, F. W., and Steves, R. J.: Kaposi's Varicelliform Eruption , Arch. Dermat. & Syph. 55:327, 1947. 14. Blattner, R. J.; Heys, F. M., and Harrison, M. L. K.: Etiology of Kaposi's Varicelliform Eruption , J. Pediat. 27:207, 1945. 15. Blank, H., and Rake, G.: Viral and Rickettsial Diseases of the Skin, Eye, and Mucous Membranes in Viral and Rickettsial Infections of Man , Edited by T. M. Rivers, Ed. 2, Philadelphia, J. B. Lippincott Company, 1952, p. 54. 16. Buret, F., and Lush, D.: Herpes Simplex: Studies of the Antibody Content of Human Sera , Lancet 1:629, 1939. 17. Enders, J. F.: Clinical and Immunological Studies on the Products of Plasma Fractionation , J. Clin. Invest. 23:510, 1944. 18. Miller, O. B.; Arbesman, C., and Baer, R.: Disseminated Cutaneous Herpes Simplex, (Kaposi's Varicelliform Eruption) , Arch. Dermat. & Syph. 62:477, 1950. 19. Weintraub, I. I.: Treatment of Herpes Zoster with Gamma Globulin , J. A. M. A. 157:1611, 1955. 20. Rodarte, J. G., and Williams, B. H.: Treatment of Herpes Zoster and Chicken Pox with Immune Globulin , Arch. Dermat. & Syph. 73:553, 1956. 21. Fox, M. J., and Pica, V. B.: Treatment of Eczema Vaccinatum by Specific Gamma Globulin: A Case Report , Wisconsin M. J. 55:972, 1956.

Journal

A.M.A. Archives of DermatologyAmerican Medical Association

Published: Nov 1, 1957

References