Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Treatment of Cluster Headache: A Double-blind Comparison of Oxygen v Air Inhalation

Treatment of Cluster Headache: A Double-blind Comparison of Oxygen v Air Inhalation Abstract • Nineteen men, aged 20 to 50 years, were treated in a double-blind crossover study comparing oxygen v air inhalation at 6 L/min via nonrebreathing face masks for 15 minutes or less, for up to six headaches. Patients scored their own degree of relief for each treatment as none, slight, substantial, or complete relief. The average (±SE) relief score for all oxygen-treated patients was 1.93 ± 0.22 out of a possible total score of 3.0, and for air the treatment relief score was 0.77 ± 0.23. This difference is highly statistically significant by an analysis-of-variance F test; it documents that patients with cluster headache can benefit from oxygen inhalation during acute attacks. References 1. Dexter JD, Weitzman ED: The relationship of nocturnal headaches to sleep stage patterns . Neurology 1970;20:513-518.Crossref 2. Kudrow L: Cluster Headache: Mechanisms and Management . Oxford, England, Oxford University Press, 1980, p 18. 3. Ekbom K: Nitroglycerin as a provocative agent in cluster headache . Arch Neurol 1968; 19:487-493.Crossref 4. Horton BT: The use of histamine in the treatment of specific types of headaches . JAMA 1941;116:377-383.Crossref 5. Sakai F, Meyer JS: Regional cerebral hemodynamics during migraine and cluster headaches measured by the 133Xe inhalation method . Headache 1978;18:122-132.Crossref 6. Friedman AP, Mikropoulos MD: Cluster headaches . Neurology 1958;8:653-663.Crossref 7. Sakai F, Meyer JS: Abnormal cerebrovascular reactivity in patients with migraine and cluster headache . Headache 1979;19:257-266.Crossref 8. Kudrow L: Response of cluster headache attacks to oxygen inhalation . Headache 1981; 21:1-4.Crossref 9. Ad Hoc Committee on Classification of Headache: Classification of headache . JAMA 1962;179:717-718.Crossref 10. Jenrich RI, Sampson P: General mixed model analysis of variance , in Dixon WJ (ed): BMDP Statistical Software . Berkeley, Calif, University of California Press, 1981, pp 413-426. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Neurology American Medical Association

Treatment of Cluster Headache: A Double-blind Comparison of Oxygen v Air Inhalation

Archives of Neurology , Volume 42 (4) – Apr 1, 1985

Loading next page...
 
/lp/american-medical-association/treatment-of-cluster-headache-a-double-blind-comparison-of-oxygen-v-HMv7wRZd9o
Publisher
American Medical Association
Copyright
Copyright © 1985 American Medical Association. All Rights Reserved.
ISSN
0003-9942
eISSN
1538-3687
DOI
10.1001/archneur.1985.04060040072015
Publisher site
See Article on Publisher Site

Abstract

Abstract • Nineteen men, aged 20 to 50 years, were treated in a double-blind crossover study comparing oxygen v air inhalation at 6 L/min via nonrebreathing face masks for 15 minutes or less, for up to six headaches. Patients scored their own degree of relief for each treatment as none, slight, substantial, or complete relief. The average (±SE) relief score for all oxygen-treated patients was 1.93 ± 0.22 out of a possible total score of 3.0, and for air the treatment relief score was 0.77 ± 0.23. This difference is highly statistically significant by an analysis-of-variance F test; it documents that patients with cluster headache can benefit from oxygen inhalation during acute attacks. References 1. Dexter JD, Weitzman ED: The relationship of nocturnal headaches to sleep stage patterns . Neurology 1970;20:513-518.Crossref 2. Kudrow L: Cluster Headache: Mechanisms and Management . Oxford, England, Oxford University Press, 1980, p 18. 3. Ekbom K: Nitroglycerin as a provocative agent in cluster headache . Arch Neurol 1968; 19:487-493.Crossref 4. Horton BT: The use of histamine in the treatment of specific types of headaches . JAMA 1941;116:377-383.Crossref 5. Sakai F, Meyer JS: Regional cerebral hemodynamics during migraine and cluster headaches measured by the 133Xe inhalation method . Headache 1978;18:122-132.Crossref 6. Friedman AP, Mikropoulos MD: Cluster headaches . Neurology 1958;8:653-663.Crossref 7. Sakai F, Meyer JS: Abnormal cerebrovascular reactivity in patients with migraine and cluster headache . Headache 1979;19:257-266.Crossref 8. Kudrow L: Response of cluster headache attacks to oxygen inhalation . Headache 1981; 21:1-4.Crossref 9. Ad Hoc Committee on Classification of Headache: Classification of headache . JAMA 1962;179:717-718.Crossref 10. Jenrich RI, Sampson P: General mixed model analysis of variance , in Dixon WJ (ed): BMDP Statistical Software . Berkeley, Calif, University of California Press, 1981, pp 413-426.

Journal

Archives of NeurologyAmerican Medical Association

Published: Apr 1, 1985

References