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TREATMENT OF CHROMOBLASTOMYCOSIS WITH CALCIFEROL: Report of Three Cases

TREATMENT OF CHROMOBLASTOMYCOSIS WITH CALCIFEROL: Report of Three Cases Abstract This report deals with the results of the treatment of chromoblastomycosis with large doses of calciferol. The use of calciferol in the treatment of this disorder originated with Latapí,* who believes that calciferol dissolves the granulomatous infiltrate of tuberculous diseases and thus enables the body to destroy the organism. Since the histologic changes in chromoblastomycosis are also granulomatous in character, it occurred to me to use calciferol in patients showing the extensive nodules and patches with a hard, verrucous surface typical of the advanced stages of the disease. Previous treatment had failed to benefit these patients. The high incidence of chromoblastomycosis in Costa Rica presents a serious problem. REPORT OF CASES Case 1.—A 62-year-old man, a carpenter, was seen in the outpatient department of the hospital on Jan. 7, 1953, with the history of having injured his hand on a piece of wood while at work a year previously. A References 1. Latapí, F.: Personal communication to the author. 2. Sterogyl 15 was supplied by the Laboratories Group Roussel, Paris, France. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Dermatology & Syphilology American Medical Association

TREATMENT OF CHROMOBLASTOMYCOSIS WITH CALCIFEROL: Report of Three Cases

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Publisher
American Medical Association
Copyright
Copyright © 1954 American Medical Association. All Rights Reserved.
ISSN
0096-5979
DOI
10.1001/archderm.1954.01540230115015
Publisher site
See Article on Publisher Site

Abstract

Abstract This report deals with the results of the treatment of chromoblastomycosis with large doses of calciferol. The use of calciferol in the treatment of this disorder originated with Latapí,* who believes that calciferol dissolves the granulomatous infiltrate of tuberculous diseases and thus enables the body to destroy the organism. Since the histologic changes in chromoblastomycosis are also granulomatous in character, it occurred to me to use calciferol in patients showing the extensive nodules and patches with a hard, verrucous surface typical of the advanced stages of the disease. Previous treatment had failed to benefit these patients. The high incidence of chromoblastomycosis in Costa Rica presents a serious problem. REPORT OF CASES Case 1.—A 62-year-old man, a carpenter, was seen in the outpatient department of the hospital on Jan. 7, 1953, with the history of having injured his hand on a piece of wood while at work a year previously. A References 1. Latapí, F.: Personal communication to the author. 2. Sterogyl 15 was supplied by the Laboratories Group Roussel, Paris, France.

Journal

A.M.A. Archives of Dermatology & SyphilologyAmerican Medical Association

Published: Nov 1, 1954

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