Key PointsQuestionWhat is known about the clinical and histopathologic features and treatment of childhood-onset lupus erythematosus panniculitis? FindingsIn this case series describing 4 patients with childhood-onset lupus erythematosus panniculitis refractory to many therapies, improvement was noted after treatment with rituximab. MeaningLupus erythematosus panniculitis is a rare and disfiguring cutaneous disease in childhood with no criterion standard therapies; however, the findings from this case series suggest that rituximab may be an effective and well-tolerated treatment.
JAMA Dermatology – American Medical Association
Published: May 12, 2020