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Treatment of Childhood-Onset Lupus Erythematosus Panniculitis With Rituximab

Treatment of Childhood-Onset Lupus Erythematosus Panniculitis With Rituximab Key PointsQuestionWhat is known about the clinical and histopathologic features and treatment of childhood-onset lupus erythematosus panniculitis? FindingsIn this case series describing 4 patients with childhood-onset lupus erythematosus panniculitis refractory to many therapies, improvement was noted after treatment with rituximab. MeaningLupus erythematosus panniculitis is a rare and disfiguring cutaneous disease in childhood with no criterion standard therapies; however, the findings from this case series suggest that rituximab may be an effective and well-tolerated treatment. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Dermatology American Medical Association

Treatment of Childhood-Onset Lupus Erythematosus Panniculitis With Rituximab

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Publisher
American Medical Association
Copyright
Copyright 2020 American Medical Association. All Rights Reserved.
ISSN
2168-6068
eISSN
2168-6084
DOI
10.1001/jamadermatol.2019.4984
Publisher site
See Article on Publisher Site

Abstract

Key PointsQuestionWhat is known about the clinical and histopathologic features and treatment of childhood-onset lupus erythematosus panniculitis? FindingsIn this case series describing 4 patients with childhood-onset lupus erythematosus panniculitis refractory to many therapies, improvement was noted after treatment with rituximab. MeaningLupus erythematosus panniculitis is a rare and disfiguring cutaneous disease in childhood with no criterion standard therapies; however, the findings from this case series suggest that rituximab may be an effective and well-tolerated treatment.

Journal

JAMA DermatologyAmerican Medical Association

Published: May 12, 2020

References