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Treating Hypertension in the Elderly

Treating Hypertension in the Elderly Research Original Investigation Antihypertensive Medications and Serious Falls Invited Commentary Should the Risk of Falls Be Part of the Equation? Sarah D. Berry, MD, MPH; Douglas P. Kiel, MD, MPH Hypertension affects two-thirds of persons 60 years or older. An interesting observation from pharmacoepidemiologic Treatment of hypertension has clear cardiovascular benefits studies of antihypertensive medications and injurious falls is in younger adults, but, as is true for most classes of medica- that these drugs affect falls differently according to duration tions, it is less clear whether of use. A population-based, self-controlled case series found these benefits extend to the that users of antihypertensive medications are at greatest risk Related article page 588 growing elderly population. for hip fracture in the 45 days after drug initiation. Using a Medications used to treat hy- case-crossover study design, investigators in one study found pertension are often prescribed for the remaining years of a pa- an increased risk of hip fracture within the first 7 days after tient’s life, increasing the risk of adverse effects and financial initiation of a loop diuretic and within 8 to 14 days after ini- strain. Clinicians must balance the uncertain cardiovascular tiation of thiazide diuretic treatment. These http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Internal Medicine American Medical Association

Treating Hypertension in the Elderly

JAMA Internal Medicine , Volume 174 (4) – Apr 1, 2014

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Publisher
American Medical Association
Copyright
Copyright 2014 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6106
eISSN
2168-6114
DOI
10.1001/jamainternmed.2013.13746
pmid
24566852
Publisher site
See Article on Publisher Site

Abstract

Research Original Investigation Antihypertensive Medications and Serious Falls Invited Commentary Should the Risk of Falls Be Part of the Equation? Sarah D. Berry, MD, MPH; Douglas P. Kiel, MD, MPH Hypertension affects two-thirds of persons 60 years or older. An interesting observation from pharmacoepidemiologic Treatment of hypertension has clear cardiovascular benefits studies of antihypertensive medications and injurious falls is in younger adults, but, as is true for most classes of medica- that these drugs affect falls differently according to duration tions, it is less clear whether of use. A population-based, self-controlled case series found these benefits extend to the that users of antihypertensive medications are at greatest risk Related article page 588 growing elderly population. for hip fracture in the 45 days after drug initiation. Using a Medications used to treat hy- case-crossover study design, investigators in one study found pertension are often prescribed for the remaining years of a pa- an increased risk of hip fracture within the first 7 days after tient’s life, increasing the risk of adverse effects and financial initiation of a loop diuretic and within 8 to 14 days after ini- strain. Clinicians must balance the uncertain cardiovascular tiation of thiazide diuretic treatment. These

Journal

JAMA Internal MedicineAmerican Medical Association

Published: Apr 1, 2014

References