Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Transcatheter Valve Replacement for Bicuspid Aortic Stenosis

Transcatheter Valve Replacement for Bicuspid Aortic Stenosis Opinion EDITORIAL Catherine M. Otto, MD; David E. Newby, MD Bicuspid aortic valve (BAV) disease is a congenital condition cluded.Moredataarethereforeneededonproceduralsuccessand that affects an estimated 1% of the world’s population. While outcomes of TAVR for severe aortic stenosis in patients with BAV. initial valve function is relatively normal and has little early clini- In this issue of JAMA, Makkar and colleagues present ob- cal consequence, progressive servational data from 7058 patients with BAV at low surgical risk valve fibrosis and calcifica- who underwent TAVR and who accounted for 4.4% of low-risk Related article page 1034 tion eventually results in se- participants (n = 159 661) included in the Society of Thoracic vere aortic stenosis, requiring aortic valve replacement in nearly Surgeons (STS)/American College of Cardiology (ACC) Trans- all patients with BAV in later life. catheter Valve Therapies Registry from 2015 to 2020. In the pri- BAV disease has a wide phenotypic spectrum with valve mary analysis, involving 3168 propensity-matched pairs of pa- anatomy characterized by fusion of 2 of the normal 3 leaflets tients with bicuspid and trileaflet aortic stenosis at low surgical (90%-95%) or 2 equal hemispherical leaflets (5%-7% of risk, procedural success was not significantly different be- 2,3 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Transcatheter Valve Replacement for Bicuspid Aortic Stenosis

JAMA , Volume 326 (11) – Sep 21, 2021

Loading next page...
 
/lp/american-medical-association/transcatheter-valve-replacement-for-bicuspid-aortic-stenosis-yyCyspT5E9
Publisher
American Medical Association
Copyright
Copyright 2021 American Medical Association. All Rights Reserved.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2021.13229
Publisher site
See Article on Publisher Site

Abstract

Opinion EDITORIAL Catherine M. Otto, MD; David E. Newby, MD Bicuspid aortic valve (BAV) disease is a congenital condition cluded.Moredataarethereforeneededonproceduralsuccessand that affects an estimated 1% of the world’s population. While outcomes of TAVR for severe aortic stenosis in patients with BAV. initial valve function is relatively normal and has little early clini- In this issue of JAMA, Makkar and colleagues present ob- cal consequence, progressive servational data from 7058 patients with BAV at low surgical risk valve fibrosis and calcifica- who underwent TAVR and who accounted for 4.4% of low-risk Related article page 1034 tion eventually results in se- participants (n = 159 661) included in the Society of Thoracic vere aortic stenosis, requiring aortic valve replacement in nearly Surgeons (STS)/American College of Cardiology (ACC) Trans- all patients with BAV in later life. catheter Valve Therapies Registry from 2015 to 2020. In the pri- BAV disease has a wide phenotypic spectrum with valve mary analysis, involving 3168 propensity-matched pairs of pa- anatomy characterized by fusion of 2 of the normal 3 leaflets tients with bicuspid and trileaflet aortic stenosis at low surgical (90%-95%) or 2 equal hemispherical leaflets (5%-7% of risk, procedural success was not significantly different be- 2,3

Journal

JAMAAmerican Medical Association

Published: Sep 21, 2021

References