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Trabecular Carcinoma of the Skin

Trabecular Carcinoma of the Skin Abstract Five patients had trabecular carcinomas of the skin. The growths originate within the dermis or in the immediate subcutis, and display a uniform morphology. They are composed of solid trabeculae that lack definite acini. A derivation from cells that are capable of reproducing primitive sudoriferous structures is postulated. The lesions have been encountered in elderly patients of both sexes, and the larger tumors have disseminated actively by lymphatic pathways. Trabecular carcinomas may occasion diagnostic difficulty, for they may be misinterpreted as cutaneous metastases from visceral cancers. The histological features of these tumors are not sufficiently distinctive to permit differentiation from anaplastic metastatic carcinomas. Confirmation of their primary dermal origin is dependent upon the clinical outcome. Familiarity with their existence is, however, of importance in the evaluation of cutaneous malignancy. References 1. Elliot GB, Ramsey DW: Sweat gland carcinoma. Ann Surg 144:99-106, 1956.Crossref 2. Grant RA: Sweat gland carcinoma with metastases. JAMA 173:490-492, 1960.Crossref 3. Kay S, Hall WEB: Sweat gland carcinoma with proved metastases. Cancer 7:373-376, 1954.Crossref 4. Keasbey LE, Hadley GG: Clear cell hidradenoma. Cancer 7:934-952, 1954.Crossref 5. Kersting DW: Clear cell hidradenoma and hidradenocarcinoma. Arch Derm 87:323-332, 1963.Crossref 6. Stout AP, Cooley SGE: Carcinoma of sweat glands. Cancer 4:521-536, 1951.Crossref 7. Teloh HA: Sweat gland carcinoma. Cancer 8:1003-1008, 1955.Crossref 8. Teloh HA, Balkin RE, Grier JP: Metastasising sweat gland carcinoma: Report of a case. Arch Derm 76:80-86, 1957.Crossref 9. Mackenzie DH: A clear-cell hidradenocarcinoma with metastases. Cancer 10:1021-1023, 1957.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Trabecular Carcinoma of the Skin

Archives of Dermatology , Volume 105 (1) – Jan 1, 1972

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Publisher
American Medical Association
Copyright
Copyright © 1972 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1972.01620040075020
Publisher site
See Article on Publisher Site

Abstract

Abstract Five patients had trabecular carcinomas of the skin. The growths originate within the dermis or in the immediate subcutis, and display a uniform morphology. They are composed of solid trabeculae that lack definite acini. A derivation from cells that are capable of reproducing primitive sudoriferous structures is postulated. The lesions have been encountered in elderly patients of both sexes, and the larger tumors have disseminated actively by lymphatic pathways. Trabecular carcinomas may occasion diagnostic difficulty, for they may be misinterpreted as cutaneous metastases from visceral cancers. The histological features of these tumors are not sufficiently distinctive to permit differentiation from anaplastic metastatic carcinomas. Confirmation of their primary dermal origin is dependent upon the clinical outcome. Familiarity with their existence is, however, of importance in the evaluation of cutaneous malignancy. References 1. Elliot GB, Ramsey DW: Sweat gland carcinoma. Ann Surg 144:99-106, 1956.Crossref 2. Grant RA: Sweat gland carcinoma with metastases. JAMA 173:490-492, 1960.Crossref 3. Kay S, Hall WEB: Sweat gland carcinoma with proved metastases. Cancer 7:373-376, 1954.Crossref 4. Keasbey LE, Hadley GG: Clear cell hidradenoma. Cancer 7:934-952, 1954.Crossref 5. Kersting DW: Clear cell hidradenoma and hidradenocarcinoma. Arch Derm 87:323-332, 1963.Crossref 6. Stout AP, Cooley SGE: Carcinoma of sweat glands. Cancer 4:521-536, 1951.Crossref 7. Teloh HA: Sweat gland carcinoma. Cancer 8:1003-1008, 1955.Crossref 8. Teloh HA, Balkin RE, Grier JP: Metastasising sweat gland carcinoma: Report of a case. Arch Derm 76:80-86, 1957.Crossref 9. Mackenzie DH: A clear-cell hidradenocarcinoma with metastases. Cancer 10:1021-1023, 1957.Crossref

Journal

Archives of DermatologyAmerican Medical Association

Published: Jan 1, 1972

References