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Toxic Epidermal Necrolysis: Acute Pemphigus

Toxic Epidermal Necrolysis: Acute Pemphigus Abstract A striking dermatologic disease resembling scalding, namely acute pemphigus, has been recently renamed toxic epidermal necrolysis by Lyell,1 or epidermolysis necroticans combustiformis by Soltermann.2 Already, mention has been made in the literature of a score or more examples under these names, and the disease is apparently not rare.3 However, no recent mention of it has been made in the American literature, and for this reason the following example is reported. Report of a Case A Negro girl, aged 22 months, was well until March 11, 1960, when she had an upper respiratorytract infection with cough, coryza, and otitis media but no pharyngitis. She received, by injection, aqueous and procaine penicillin on March 13, and an oral mixed sulfonamide preparation for 10 days. Aspirin and a cough medicine containing saccharated thyme were also given. By March 25, she felt well again. On March 30, the child fell References 1. Lyell, A.: Toxic Epidermal Necrolysis: An Eruption Resembling Scalding of the Skin , Brit. J. Dermat. 68:355-361, 1960.Crossref 2. Soltermann, W.: Toxic Epidermal Necrolysis (Lyell): Neues Syndrom oder besonders schwere Verlaufsform einer Allergodermie?) , Dermatologica 118:265-278, 1959.Crossref 3. Walker, J.: Toxic Epidermal Necrolysis , Brit. M.J. 2:1094, 1959.Crossref 4. Gill, N.: A Case of Toxic Epidermal Necrolysis (Lyell) , Brit. J. Dermat. 70:302-303, 1958.Crossref 5. Rook, A.: Toxic Epidermal Necrolysis (Lyell) , Arch. belges dermat. et syph. 13:391-398, 1958. 6. Lang, R., and Walker, J.: An Unusual Bullous Eruption , South African M.J. 30:97-98, 1956. 7. Lang, R., and Walker, J.: Toxic Epidermal Necrolysis , South African M.J. 31:713-716, 1957. 8. Jaeger, H., and Delacretaz, J.: Eruption médicamenteuse grave à l'actinomycine (erythrodermie pemphigoïde) , Dermatologica 110:53, 1955.Crossref 9. Frain-Bell, W., and Koblenzer, P.: Two Cases of Toxic Epidermal Necrolysis , Proc. Roy. Soc. Med. 52:1029-1031, 1959. 10. Catto, J. V. F.: Toxic Epidermal Necrolysis , Brit. M.J. 2:544-545, 1959.Crossref 11. Evans, C.: Toxic Epidermal Necrolysis , Brit. M.J. 2:827, 1959.Crossref 12. Ruskin, D. B.: Fulminating Dermatitis Bullosa Medicamentosa Due to "Mesantoin," J.A.M.A. 137:1031-1035, 1948.Crossref 13. Jaeger, H.: Eruption mortelle due aux sels d'or erythematobulleuse, pemphigoïde, à marche rapide , Dermatologica 103:280-282, 1951.Crossref 14. Haber, H., in discussion of article cited by Frain-Bell and Koblenzer.9 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Toxic Epidermal Necrolysis: Acute Pemphigus

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Publisher
American Medical Association
Copyright
Copyright © 1960 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1960.01580060057006
Publisher site
See Article on Publisher Site

Abstract

Abstract A striking dermatologic disease resembling scalding, namely acute pemphigus, has been recently renamed toxic epidermal necrolysis by Lyell,1 or epidermolysis necroticans combustiformis by Soltermann.2 Already, mention has been made in the literature of a score or more examples under these names, and the disease is apparently not rare.3 However, no recent mention of it has been made in the American literature, and for this reason the following example is reported. Report of a Case A Negro girl, aged 22 months, was well until March 11, 1960, when she had an upper respiratorytract infection with cough, coryza, and otitis media but no pharyngitis. She received, by injection, aqueous and procaine penicillin on March 13, and an oral mixed sulfonamide preparation for 10 days. Aspirin and a cough medicine containing saccharated thyme were also given. By March 25, she felt well again. On March 30, the child fell References 1. Lyell, A.: Toxic Epidermal Necrolysis: An Eruption Resembling Scalding of the Skin , Brit. J. Dermat. 68:355-361, 1960.Crossref 2. Soltermann, W.: Toxic Epidermal Necrolysis (Lyell): Neues Syndrom oder besonders schwere Verlaufsform einer Allergodermie?) , Dermatologica 118:265-278, 1959.Crossref 3. Walker, J.: Toxic Epidermal Necrolysis , Brit. M.J. 2:1094, 1959.Crossref 4. Gill, N.: A Case of Toxic Epidermal Necrolysis (Lyell) , Brit. J. Dermat. 70:302-303, 1958.Crossref 5. Rook, A.: Toxic Epidermal Necrolysis (Lyell) , Arch. belges dermat. et syph. 13:391-398, 1958. 6. Lang, R., and Walker, J.: An Unusual Bullous Eruption , South African M.J. 30:97-98, 1956. 7. Lang, R., and Walker, J.: Toxic Epidermal Necrolysis , South African M.J. 31:713-716, 1957. 8. Jaeger, H., and Delacretaz, J.: Eruption médicamenteuse grave à l'actinomycine (erythrodermie pemphigoïde) , Dermatologica 110:53, 1955.Crossref 9. Frain-Bell, W., and Koblenzer, P.: Two Cases of Toxic Epidermal Necrolysis , Proc. Roy. Soc. Med. 52:1029-1031, 1959. 10. Catto, J. V. F.: Toxic Epidermal Necrolysis , Brit. M.J. 2:544-545, 1959.Crossref 11. Evans, C.: Toxic Epidermal Necrolysis , Brit. M.J. 2:827, 1959.Crossref 12. Ruskin, D. B.: Fulminating Dermatitis Bullosa Medicamentosa Due to "Mesantoin," J.A.M.A. 137:1031-1035, 1948.Crossref 13. Jaeger, H.: Eruption mortelle due aux sels d'or erythematobulleuse, pemphigoïde, à marche rapide , Dermatologica 103:280-282, 1951.Crossref 14. Haber, H., in discussion of article cited by Frain-Bell and Koblenzer.9

Journal

Archives of DermatologyAmerican Medical Association

Published: Dec 1, 1960

References