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Total Sleep Deprivation on Endogenous Depression

Total Sleep Deprivation on Endogenous Depression Abstract • Ten endogenous depressive patients were deprived of sleep for two whole nights according to the following schedule: sleep/sleep deprivation/sleep/sleep deprivation/sleep. No drugs were administered. Experimental conditions were as neutral as possible. Blind and nonblind ratings were taken. The patients were generally rated as improved after sleep deprivation, but a substantial effect, though temporary with rapid relapse, occurred in only two cases. After subsequent sleep, relapse followed as a rule. The net antidepressive effect of the total procedure was slightly more than nil. References 1. Schulte W: Klinische Erfahrungen über das Herausgeraten aus der melancholischen Phase , in Hippius H, Selbach H (eds): Das depressive Syndrom . München, Urban Schwarzenberg, 1969, pp 415-420. 2. Schulte W: Zum Problem der Provokation und Kupierung von melancholischen Phasen . Schweiz Arch Neurol Neurochir Psychiatr 109:427-435, 1971. 3. Pflug B, Tölle R: Therapie endogener Depressionen durch Schlafentzug . Nervenarzt 42:117-124, 1971. 4. Pflug B: Über den Schlafentzug in der ambulanten Therapie endogener Depression . Nervenarzt 43:614-622, 1972. 5. Pflug B: Therapeutic aspects of sleep deprivation , in Koella WP, Levin P (eds): Sleep: Physiology, Biochemistry, Psychology, Pharmacology, Clinical Implications . Basel, Switzerland, Karger, 1973. 6. Webb WB, Agnew HW: Sleep and Dreams . Dubuque, Iowa, WC Brown Co, 1973. 7. Hamilton M: Development of a rating scale for primary depressive illness . Br J Soc Clin Psychol 6:278-296, 1967.Crossref 8. Aitken RCB: Measurement of feelings using visual analogue scales . Proc R Soc Med 62:989-993, 1969. 9. Zeally AK, Aitken RCB: Measurement of mood . Proc R Soc Med 62:993-996, 1969. 10. Hollander M, Wolfe DA: Nonparametric Statistical Methods . New York, John Wiley & Sons Inc, 1973. 11. Fleiss JL: Statistical Methods for Rates and Proportions . New York, John Wiley & Sons Inc, 1973. 12. Aitken RCB, Zeally AK: Measurements of mood . Br J Hosp Med 4:215-224, 1970. 13. Stallone F, Huba GJ, Lawlor WG, et al: Longitudinal studies of diurnal variations in depression: A sample of 643 patient days . Br J Psychiatry 123:311-318, 1973.Crossref 14. Wilkinson RT: Aftereffect of sleep deprivation . J Exp Psychol 66:439-442, 1963.Crossref 15. Vogel GW, Traub AC, Ben-Horin P, et al: REM deprivation: II. The effects on depressed patients . Arch Gen Psychiatry 18:301-311, 1968.Crossref 16. Vogel GW, Thompson FC Jr, Thurmond A, et al: The effect of REM deprivation in depression , in Koella WP, Levin P (eds): Sleep: Physiology, Biochemistry, Psychology, Pharmacology, Clinical Implications . Basel, Switzerland, Karger, 1973, pp 191-195. 17. Kahneman D: Attention and Effort . Englewood Cliffs, New Jersey, Prentice-Hall Inc, 1973. 18. Zung WWK, Wilson WP, Dodson WE: Effect of depressive disorders on sleep EEG responses . Arch Gen Psychiatry 10:439-445, 1964.Crossref 19. Zung WWK: Effect of antidepressant drugs on sleeping and dreaming: III. On the depressed patient . Biol Psychiatry 1:283-287, 1969. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of General Psychiatry American Medical Association

Total Sleep Deprivation on Endogenous Depression

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Publisher
American Medical Association
Copyright
Copyright © 1975 American Medical Association. All Rights Reserved.
ISSN
0003-990X
eISSN
1598-3636
DOI
10.1001/archpsyc.1975.01760270053005
Publisher site
See Article on Publisher Site

Abstract

Abstract • Ten endogenous depressive patients were deprived of sleep for two whole nights according to the following schedule: sleep/sleep deprivation/sleep/sleep deprivation/sleep. No drugs were administered. Experimental conditions were as neutral as possible. Blind and nonblind ratings were taken. The patients were generally rated as improved after sleep deprivation, but a substantial effect, though temporary with rapid relapse, occurred in only two cases. After subsequent sleep, relapse followed as a rule. The net antidepressive effect of the total procedure was slightly more than nil. References 1. Schulte W: Klinische Erfahrungen über das Herausgeraten aus der melancholischen Phase , in Hippius H, Selbach H (eds): Das depressive Syndrom . München, Urban Schwarzenberg, 1969, pp 415-420. 2. Schulte W: Zum Problem der Provokation und Kupierung von melancholischen Phasen . Schweiz Arch Neurol Neurochir Psychiatr 109:427-435, 1971. 3. Pflug B, Tölle R: Therapie endogener Depressionen durch Schlafentzug . Nervenarzt 42:117-124, 1971. 4. Pflug B: Über den Schlafentzug in der ambulanten Therapie endogener Depression . Nervenarzt 43:614-622, 1972. 5. Pflug B: Therapeutic aspects of sleep deprivation , in Koella WP, Levin P (eds): Sleep: Physiology, Biochemistry, Psychology, Pharmacology, Clinical Implications . Basel, Switzerland, Karger, 1973. 6. Webb WB, Agnew HW: Sleep and Dreams . Dubuque, Iowa, WC Brown Co, 1973. 7. Hamilton M: Development of a rating scale for primary depressive illness . Br J Soc Clin Psychol 6:278-296, 1967.Crossref 8. Aitken RCB: Measurement of feelings using visual analogue scales . Proc R Soc Med 62:989-993, 1969. 9. Zeally AK, Aitken RCB: Measurement of mood . Proc R Soc Med 62:993-996, 1969. 10. Hollander M, Wolfe DA: Nonparametric Statistical Methods . New York, John Wiley & Sons Inc, 1973. 11. Fleiss JL: Statistical Methods for Rates and Proportions . New York, John Wiley & Sons Inc, 1973. 12. Aitken RCB, Zeally AK: Measurements of mood . Br J Hosp Med 4:215-224, 1970. 13. Stallone F, Huba GJ, Lawlor WG, et al: Longitudinal studies of diurnal variations in depression: A sample of 643 patient days . Br J Psychiatry 123:311-318, 1973.Crossref 14. Wilkinson RT: Aftereffect of sleep deprivation . J Exp Psychol 66:439-442, 1963.Crossref 15. Vogel GW, Traub AC, Ben-Horin P, et al: REM deprivation: II. The effects on depressed patients . Arch Gen Psychiatry 18:301-311, 1968.Crossref 16. Vogel GW, Thompson FC Jr, Thurmond A, et al: The effect of REM deprivation in depression , in Koella WP, Levin P (eds): Sleep: Physiology, Biochemistry, Psychology, Pharmacology, Clinical Implications . Basel, Switzerland, Karger, 1973, pp 191-195. 17. Kahneman D: Attention and Effort . Englewood Cliffs, New Jersey, Prentice-Hall Inc, 1973. 18. Zung WWK, Wilson WP, Dodson WE: Effect of depressive disorders on sleep EEG responses . Arch Gen Psychiatry 10:439-445, 1964.Crossref 19. Zung WWK: Effect of antidepressant drugs on sleeping and dreaming: III. On the depressed patient . Biol Psychiatry 1:283-287, 1969.

Journal

Archives of General PsychiatryAmerican Medical Association

Published: Sep 1, 1975

References