Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Total Pancreatectomy for Pleomorphic Carcinoma: A Five-Year Cure

Total Pancreatectomy for Pleomorphic Carcinoma: A Five-Year Cure Abstract ADENOCARCINOMA is a common type of malignant tumor that arises from the pancreas. Pleomorphic carcinoma of the pancreas is a rare lesion which may be mistaken for rhabdomyosarcoma, malignant melanoma, angiosarcoma, or some other type of unusual neoplasm.1,2 In a study of specimens at autopsy, Sommers and Meissner3 found three pleomorphic carcinomas in 142 patients who died of pancreatic neoplasm. The case of a patient who had pleomorphic carcinoma of the pancreas and in whom total pancreatectomy was performed forms the basis of this report. Report of Case A 49-year-old physician entered the Mayo Clinic in February 1960 because of a daily periumbilical cramping pain of several weeks' duration. His appetite had decreased, but there were no other symptoms except for those associated with severe diabetes which had been present for 28 years. At the time of admission, he was taking a mixture of 40 units of lente References 1. Frantz, V.: " Tumors of the Pancreas ," in Atlas of Tumor Pathology , Armed Forces Institute of Pathology, National Research Council, 1959, sec 7, pt 27 and 28, pp 36-77. 2. Jordan, G.L., Jr.: "Benign and Malignant Tumors of the Pancreas and the Periampullary Region" and "Pancreatic Resection: Subtotal Pancreatic Resection," in Howard, J.M., and Jordan, G.L., Jr., (eds.): Surgical Diseases of the Pancreas , Philadelphia: J. B. Lippincott Co., 1960, pp 449-532 and 533-583. 3. Sommers, S.C., and Meissner, W.A.: Unusual Carcinomas of the Pancreas , Arch Path 58:101-111 ( (Aug) ) 1954. 4. Bell, E.T.: Carcinoma of the Pancreas: I. A Clinical and Pathological Study of 609 Necropsied Cases. II. The Relation of Carcinoma of the Pancreas to Diabetes Mellitus , Amer J Path 33:499-523 ( (May-June) ) 1957. 5. Mongé, J.J., et al: Clinicopathologic Observations on Radical Pancreatoduodenal Resection for Peripapillary Carcinoma , Surg Gynec Obstet 118:275-283 ( (Feb) ) 1964. 6. Dennis, C., and Varco, R.L.: Survival for More Than Five Years After Pancreatoduodenectomy for Cancers of the Ampulla and Pancreatic Head , Surgery 39:92-106 ( (Jan) ) 1956. 7. Miller, E.M., and Clagett, O.T.: Survival Five Years After Radical Pancreatoduodenectomy for Carcinoma of the Head of the Pancreas , Ann Surg 134:1013-1017 ( (Dec) ) 1951.Crossref 8. Mongé, J.J.; Judd, E.S.; and Gage, R.P.: Radical Pancreatoduodenectomy: A 22-Year Experience With the Complications, Mortality Rate, and Survival Rate , Ann Surg 160:711-719 ( (Oct) ) 1964.Crossref 9. Rhoads, J.H.; Zintel, H.A.; and Helwig, J., Jr.: Results of Operations of the Whipple Type of Pancreaticoduodenal Carcinoma , Ann Surg 146:661-665 ( (Oct) ) 1957.Crossref 10. Priestley, J.T.; Comfort, M.W.; and Radcliffe, J., Jr.: Total Pancreatectomy for Hyperinsulinism Due to an Islet-Cell Adenoma: Survival and Cure at 16 Months After Operation; Presentation of Metabolic Studies , Ann Surg 119:211-221 ( (Feb) ) 1944.Crossref 11. Priestley, J.T.; Comfort, M.W.; and Sprague, R.G.: Total Pancreatectomy for Hyperinsulinism Due to Islet-Cell Adenoma: Follow-up Report Five and One-Half Years After Operation, Including Metabolic Studies , Ann Surg 130:211-217 ( (Aug) ) 1949.Crossref 12. Bartlett, M.K.: The Status of Pancreaticoduodenal Resection , Surg Clin N Amer 27:1032-1036 ( (Oct) ) 1947. 13. Brunschwig, A.: Radical Pancreatoduodenectomy for Cancer of the Head of the Pancreas , Cancer 9:1160-1162 ( (Nov-Dec) ) 1956.Crossref 14. Glenn, F., and Thorbjarnarson, B.: Carcinoma of the Pancreas , Ann Surg 159:945-955 ( (June) ) 1964.Crossref 15. Jordan, G.L., Jr.: Surgical Management of Carcinoma of the Pancreas and Periampullary Region , Amer J Surg 107:313-316 ( (Feb) ) 1964.Crossref 16. Whipple, A.O.; Parsons, W.B.; and Mullins, C.R.: Treatment of Carcinoma of the Ampulla of Vater , Ann Surg 102:763-776 ( (Oct) ) 1935.Crossref 17. Hallenbeck, G.A., et al: Report on Surgery of the Biliary System and Pancreas for 1955 , Mayo Clin Proc 31:665-670 ( (Dec 12) ) 1956. 18. Judd, E.S.: Surgery of the Biliary Tract and Pancreas , Mayo Clin Proc 39:927-938 ( (Dec) ) 1964. 19. Priestley, J.T., et al: Annual Report on Surgery of the Biliary System and Pancreas for 1956 , Mayo Clin Proc 32:605-614 ( (Oct 16) ) 1957. 20. Waugh, J.M., and Hallenbeck, G.A.: " The Pancreas ," in Davis, L. (ed.): Christopher's Textbook of Surgery , ed 7, Philadelphia: W. B. Saunders Co., 1960, pp 800-819. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

Total Pancreatectomy for Pleomorphic Carcinoma: A Five-Year Cure

Loading next page...
 
/lp/american-medical-association/total-pancreatectomy-for-pleomorphic-carcinoma-a-five-year-cure-QgosgfTzrt
Publisher
American Medical Association
Copyright
Copyright © 1966 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1966.01320200155027
Publisher site
See Article on Publisher Site

Abstract

Abstract ADENOCARCINOMA is a common type of malignant tumor that arises from the pancreas. Pleomorphic carcinoma of the pancreas is a rare lesion which may be mistaken for rhabdomyosarcoma, malignant melanoma, angiosarcoma, or some other type of unusual neoplasm.1,2 In a study of specimens at autopsy, Sommers and Meissner3 found three pleomorphic carcinomas in 142 patients who died of pancreatic neoplasm. The case of a patient who had pleomorphic carcinoma of the pancreas and in whom total pancreatectomy was performed forms the basis of this report. Report of Case A 49-year-old physician entered the Mayo Clinic in February 1960 because of a daily periumbilical cramping pain of several weeks' duration. His appetite had decreased, but there were no other symptoms except for those associated with severe diabetes which had been present for 28 years. At the time of admission, he was taking a mixture of 40 units of lente References 1. Frantz, V.: " Tumors of the Pancreas ," in Atlas of Tumor Pathology , Armed Forces Institute of Pathology, National Research Council, 1959, sec 7, pt 27 and 28, pp 36-77. 2. Jordan, G.L., Jr.: "Benign and Malignant Tumors of the Pancreas and the Periampullary Region" and "Pancreatic Resection: Subtotal Pancreatic Resection," in Howard, J.M., and Jordan, G.L., Jr., (eds.): Surgical Diseases of the Pancreas , Philadelphia: J. B. Lippincott Co., 1960, pp 449-532 and 533-583. 3. Sommers, S.C., and Meissner, W.A.: Unusual Carcinomas of the Pancreas , Arch Path 58:101-111 ( (Aug) ) 1954. 4. Bell, E.T.: Carcinoma of the Pancreas: I. A Clinical and Pathological Study of 609 Necropsied Cases. II. The Relation of Carcinoma of the Pancreas to Diabetes Mellitus , Amer J Path 33:499-523 ( (May-June) ) 1957. 5. Mongé, J.J., et al: Clinicopathologic Observations on Radical Pancreatoduodenal Resection for Peripapillary Carcinoma , Surg Gynec Obstet 118:275-283 ( (Feb) ) 1964. 6. Dennis, C., and Varco, R.L.: Survival for More Than Five Years After Pancreatoduodenectomy for Cancers of the Ampulla and Pancreatic Head , Surgery 39:92-106 ( (Jan) ) 1956. 7. Miller, E.M., and Clagett, O.T.: Survival Five Years After Radical Pancreatoduodenectomy for Carcinoma of the Head of the Pancreas , Ann Surg 134:1013-1017 ( (Dec) ) 1951.Crossref 8. Mongé, J.J.; Judd, E.S.; and Gage, R.P.: Radical Pancreatoduodenectomy: A 22-Year Experience With the Complications, Mortality Rate, and Survival Rate , Ann Surg 160:711-719 ( (Oct) ) 1964.Crossref 9. Rhoads, J.H.; Zintel, H.A.; and Helwig, J., Jr.: Results of Operations of the Whipple Type of Pancreaticoduodenal Carcinoma , Ann Surg 146:661-665 ( (Oct) ) 1957.Crossref 10. Priestley, J.T.; Comfort, M.W.; and Radcliffe, J., Jr.: Total Pancreatectomy for Hyperinsulinism Due to an Islet-Cell Adenoma: Survival and Cure at 16 Months After Operation; Presentation of Metabolic Studies , Ann Surg 119:211-221 ( (Feb) ) 1944.Crossref 11. Priestley, J.T.; Comfort, M.W.; and Sprague, R.G.: Total Pancreatectomy for Hyperinsulinism Due to Islet-Cell Adenoma: Follow-up Report Five and One-Half Years After Operation, Including Metabolic Studies , Ann Surg 130:211-217 ( (Aug) ) 1949.Crossref 12. Bartlett, M.K.: The Status of Pancreaticoduodenal Resection , Surg Clin N Amer 27:1032-1036 ( (Oct) ) 1947. 13. Brunschwig, A.: Radical Pancreatoduodenectomy for Cancer of the Head of the Pancreas , Cancer 9:1160-1162 ( (Nov-Dec) ) 1956.Crossref 14. Glenn, F., and Thorbjarnarson, B.: Carcinoma of the Pancreas , Ann Surg 159:945-955 ( (June) ) 1964.Crossref 15. Jordan, G.L., Jr.: Surgical Management of Carcinoma of the Pancreas and Periampullary Region , Amer J Surg 107:313-316 ( (Feb) ) 1964.Crossref 16. Whipple, A.O.; Parsons, W.B.; and Mullins, C.R.: Treatment of Carcinoma of the Ampulla of Vater , Ann Surg 102:763-776 ( (Oct) ) 1935.Crossref 17. Hallenbeck, G.A., et al: Report on Surgery of the Biliary System and Pancreas for 1955 , Mayo Clin Proc 31:665-670 ( (Dec 12) ) 1956. 18. Judd, E.S.: Surgery of the Biliary Tract and Pancreas , Mayo Clin Proc 39:927-938 ( (Dec) ) 1964. 19. Priestley, J.T., et al: Annual Report on Surgery of the Biliary System and Pancreas for 1956 , Mayo Clin Proc 32:605-614 ( (Oct 16) ) 1957. 20. Waugh, J.M., and Hallenbeck, G.A.: " The Pancreas ," in Davis, L. (ed.): Christopher's Textbook of Surgery , ed 7, Philadelphia: W. B. Saunders Co., 1960, pp 800-819.

Journal

Archives of SurgeryAmerican Medical Association

Published: Feb 1, 1966

References