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Tinea Versicolor Treatment

Tinea Versicolor Treatment Abstract To the Editor.— Although tinea versicolor can be successfully treated with several preparations, some agents have shortcomings, which warranted trial of another preparation.Sodium thiosulfate is slow acting and often ineffective. Tolnaftate requires prolonged use for widespread lesions.1 Selenium sulfide (2.5%) shampoo is usually effective,2-4 but there is concern for toxicity with prolonged treatment, or treatment of large areas.5Sulfur and salicylic acid have been used as fungicides, and occasionally for treatment of tinea versicolor. An easily available, safe, and cosmetically pleasant formulation was chosen, which contained 2% micropulverized sulfur and 2% salicylic acid in a shampoo base (Sebulex). Half of the patients were treated with an oil-in-water lotion (Keri Lotion) as a placebo.Thirty-nine volunteers had typical spores and hyphal segments on potassium hydroxide cellophane tape preparations of skin lesions.6 A third party randomized the subjects, using a table of random numbers, and handed out References 1. Robinson HM Jr, Raskin J: Tolnaftate, a potent topical antifungal agent . Arch Dermatol 91:372-376, 1965.Crossref 2. Albright SD III, Hitch JM: Rapid treatment of tinea versicolor with selenium sulfide . Arch Dermatol 93:460-462, 1966.Crossref 3. Levan NE: Selenium sulfide suspension in the treatment of tinea versicolor . Arch Dermatol 75:128-129, 1957.Crossref 4. Hersle K: Selenium sulfide treatment of tinea versicolor . Acta Derm Venereol 51:476-478, 1971. 5. Ransone JW, Scott NM Jr, Khoblock EC: Selenium sulfide intoxication . N Engl J Med 264:384-385, 1961.Crossref 6. Keddie F, Orr A, Liebes D: Direct staining on vinyl plastic tape demonstration of the cutaneous flora of the epidermis by the strip method . Sabouraudia 1:108-111, 1961.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Tinea Versicolor Treatment

Archives of Dermatology , Volume 110 (6) – Dec 1, 1974

Tinea Versicolor Treatment

Abstract

Abstract To the Editor.— Although tinea versicolor can be successfully treated with several preparations, some agents have shortcomings, which warranted trial of another preparation.Sodium thiosulfate is slow acting and often ineffective. Tolnaftate requires prolonged use for widespread lesions.1 Selenium sulfide (2.5%) shampoo is usually effective,2-4 but there is concern for toxicity with prolonged treatment, or treatment of large areas.5Sulfur and salicylic acid have been used as...
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Publisher
American Medical Association
Copyright
Copyright © 1974 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1974.01630120088025
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor.— Although tinea versicolor can be successfully treated with several preparations, some agents have shortcomings, which warranted trial of another preparation.Sodium thiosulfate is slow acting and often ineffective. Tolnaftate requires prolonged use for widespread lesions.1 Selenium sulfide (2.5%) shampoo is usually effective,2-4 but there is concern for toxicity with prolonged treatment, or treatment of large areas.5Sulfur and salicylic acid have been used as fungicides, and occasionally for treatment of tinea versicolor. An easily available, safe, and cosmetically pleasant formulation was chosen, which contained 2% micropulverized sulfur and 2% salicylic acid in a shampoo base (Sebulex). Half of the patients were treated with an oil-in-water lotion (Keri Lotion) as a placebo.Thirty-nine volunteers had typical spores and hyphal segments on potassium hydroxide cellophane tape preparations of skin lesions.6 A third party randomized the subjects, using a table of random numbers, and handed out References 1. Robinson HM Jr, Raskin J: Tolnaftate, a potent topical antifungal agent . Arch Dermatol 91:372-376, 1965.Crossref 2. Albright SD III, Hitch JM: Rapid treatment of tinea versicolor with selenium sulfide . Arch Dermatol 93:460-462, 1966.Crossref 3. Levan NE: Selenium sulfide suspension in the treatment of tinea versicolor . Arch Dermatol 75:128-129, 1957.Crossref 4. Hersle K: Selenium sulfide treatment of tinea versicolor . Acta Derm Venereol 51:476-478, 1971. 5. Ransone JW, Scott NM Jr, Khoblock EC: Selenium sulfide intoxication . N Engl J Med 264:384-385, 1961.Crossref 6. Keddie F, Orr A, Liebes D: Direct staining on vinyl plastic tape demonstration of the cutaneous flora of the epidermis by the strip method . Sabouraudia 1:108-111, 1961.Crossref

Journal

Archives of DermatologyAmerican Medical Association

Published: Dec 1, 1974

References