Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You and Your Team.

Learn More →

Tinea Versicolor in Steroid-Treated Patients: Incidence in Patients with Chronic Ulcerative Colitis and Regional Enteritis Treated with Corticotropin and Corticosteroids

Tinea Versicolor in Steroid-Treated Patients: Incidence in Patients with Chronic Ulcerative... Abstract Introduction Since the advent and widespread use of corticosteroids much has been written about the undesirable effects of these drugs. In the past decade the influence of corticosteroids on cutaneous and systemic fungous infections in man and animals has received its share of attention.1-4 However, no systematic research into the possible effects of corticosteroids on tinea versicolor was available, although it was our own clinical impression that there was a higher than expected incidence of this infection in patients with Cushing's syndrome. This observation was confirmed by examining the charts of the 22 patients with Cushing's syndrome hospitalized at The University of Chicago Clinics since 1948. It was found that 3 of these patients had tinea versicolor infections, substantiated by positive KOH preparations. It therefore seemed worthwhile to study the incidence of tinea versicolor in a large number of patients treated with adrenal steroids and corticotropin, as compared with References 1. Burns, R. E.: Fungous Disease as a Complication of Steroid Therapy , A.M.A. Arch. Derm. 77:686, 1958.Crossref 2. Mankowski, Z. T.: Influence of Hormonal Conditions on Experimental Fungus Infection , in Therapy of Fungus Diseases , edited by T. A. Sternberg and V. D. Newcomer, Boston, Little, Brown & Company, 1955. 3. Torack, R. M.: Fungous Infections Associated with Antibiotic and Steroid Therapy , Amer. J. Med. 22:872, 1957.Crossref 4. Mankowski, Z. T., and Littleton, B. J.: Action of Cortisone and ACTH on Experimental Fungus Infections , Antibiot. Chemother. 4:253, 1954. 5. Peck, S. M.; Rosenfeld, H.; Leifer, W., and Bierman, W.: Role of Sweat as a Fungicide , Arch. Derm. Syph. 39:126, 1939.Crossref 6. Rothman, S.; Smiljanic, A. M., and Shapiro, A. L.: Fungistatic Action of Hair Fat on Microsporum Audouini , Proc. Soc. Exp. Biol. Med. 60:394, 1945.Crossref 7. Rothman, S.; Smiljanic, A. M.; Shapiro, A. L., and Weitkamp, A. W.: The Spontaneous Cure of Tinea Capitis in Puberty , J. Invest. Derm. 8:81, 1947.Crossref 8. Lewis, G. M.; Hopper, M. E.; Wilson, J. W., and Plunkett, O. A.: An Introduction to Medical Mycology , Ed. 4, Chicago, Year Book Medical Publishers, Inc., 1958, p. 165. 9. Conant, N. F.; Smith, D. T.; Roger, D. B.; Callaway, J. L., and Martin, D. S.: Manual of Clinical Mycology , Ed. 2, Philadelphia, W. B. Saunders Company, 1954, p. 363. 10. Moore, M.: Cultivation of Malassezia Furfur, Etiological Agent of Pityriasis (Tinea) Versicolor , Mycopathologia 1:53, 1938.Crossref 11. Rothman, S.; Smiljanic, A. M., and Murphy, J. C.: The Nitrogenous Material on Normal Human Skin , J. Invest. Derm. 13:317, 1949.Crossref 12. Rothman, S., and Sullivan, M. B.: Amino Acids on the Normal Human Skin Surface , J. Invest. Derm. 13:319, 1949.Crossref 13. Consden, R.; Gordon, A. H., and Martin, A. J. P.: The Identification of Lower Peptides in Complex Mixtures , Biochem. J. 41:590, 1947. 14. Hardy, T. L.; Holland, D. O., and Nayler, J. H. C.: One-Phase Solvent Mixtures for the Separation of Amino Acids , Analyt. Chem. 27: 971, 1955.Crossref 15. Moore, S., and Stein, W. H.: A Modified Ninhydrin Reagent for the Photometric Determination of Amino Acids and Related Compounds , J. Biol. Chem. 211:907, 1954. 16. Block, R. J.; Durrum, E. L., and Zweig, G.: A Manual of Paper Chromatography and Paper Electrophoresis , Ed. 2, New York, Academic Press, Inc., 1958, p. 99. 17. Stein, W. H., and Moore, S.: Electrolytic Desalting of Amino Acids: Conversion of Arginine to Ornithine , J. Biol. Chem. 190:103, 1951. 18. Clarke, J. T.; Elian, E., and Schwachman, H.: Components of Sweat , Amer. J. Dis. Child. 101:490, 1961.Crossref 19. Leonhardi, G.; Glasenapp, I., and Brühl, G.: Die Freien Aminosaüren der Menschlichen Haut , Hoppe Seyler's Z. Physiol. Chem. 292:89, 1953.Crossref 20. Boughton, B.; Hodgson-Jones, I. S.; MacKenna, R. M. B., and Wormall, A.: Some Observations on the Nature, Origin, and Possible Functions of Squalene and Other Hydrocarbons of Human Sebum , J. Invest. Derm. 24:179, 1955.Crossref 21. Wheatley, V. R.: The Chemistry of Sebum and Some Other Aspects of Skin Chemistry, Ph.D. Thesis, London, St. Bartholomew Medical College, University of London, 1950. 22. Boughton, B., and Wheatley, V. R.: The Fatty Acid Composition of the Skin Surface Fat ('Sebum') of Normal Human Subjects , J. Invest. Derm. 33:49, 1959.Crossref 23. James, A. T., and Martin, A. J. P.: Gas-Liquid Partition Chromatography: The Separation and Micro-Estimation of Volatile Fatty Acids from Formic to Dodecanoic Acid , Biochem. J. 50:679, 1952. 24. James, A. T., and Martin, A. J. P.: Gas-Liquid Chromatography: The Separation and Identification of the Methyl Esters of Saturated and Unsaturated Acids from Formic to n-Octadecanoic Acid , Biochem. J. 63:144, 1956. 25. Keulemans, A. I. M.: Gas Chromatography , edited by C. G. Verver, Ed. 2, New York, Reinhold Publishing Corporation, 1959, p. 33. 26. Kligman, A. M.; Baldridge, G. D., Rebell, G., and Pillsbury, D. M.: The Effect of Cortisone on the Pathologic Responses of Guinea Pigs Infected Cutaneously with Fungi, Viruses, and Bacteria , J. Lab. Clin. Med. 37:615, 1951. 27. Reiss, F., and Caroline, L.: The Influence of ACTH and Cortisone upon Experimental Achorion Quinckeanum Infection and upon Anaphylaxis in Guinea Pigs , J. Invest. Derm. 19:365, 1952.Crossref 28. Sonck, C. E., and Miescher, G.: Der Einfluss von Cortison auf die Meerschweinchentrichophytie , Bull. Schweiz. Akad. Med. Wiss. 8:220, 1952. 29. Jadassohn, W.; Mach, R. S., and Nardin, J.: Effet de la cortisone sur la mycose expérimentale du cobaye , Acta endocr. Kbh. 6:351, 1951. 30. Pillsbury, D. M., and Jacobson, C.: Cushing's Syndrome Complicated by Generalized Trichophyton Rubrum Infection, Society Transactions , A.M.A. Arch. Derm. Syph. 67:436, 1953. 31. Lorincz, A. L., and Reisner, J. E.: Case Report, Program of the Atlantic Dermatologic Conference, Washington, D.C., March 26, 1955. 32. Cremer, G.: The Influence of Adrenocortical Hormones on Dermatomycoses: Especially in the Cushing Syndrome , Dermatologica (Basel) 111: 285, 1955.Crossref 33. Nelson, L. M., and McNiece, K. J.: Recurrent Cushing's Syndrome with Trichophyton Rubrum Infection , A.M.A. Arch. Derm. 80:700, 1959.Crossref 34. Canizares, O.; Shatin, H., and Kellert, A. J.: Cushing's Syndrome and Dermatomycosis , A.M.A. Arch. Derm. 80:705, 1959.Crossref 35. Burke, R. C.: Tinea Versicolor: Susceptibility Factors and Experimental Infection in Human Beings , J. Invest. Derm. 36:389, 1961. 36. Adamson, H. G.: Pityriasis Versicolor with Subsequent Leucodermic Patches , Brit. J. Derm. 61:322, 1949.Crossref 37. Vilanova, X., and Cardenal, C.: in Handbook of Tropical Dermatology and Medical Mycology , edited by R. D. G. Ph. Simons, Amsterdam, Elsevier Press, Inc., 1953, p. 1102. 38. Fischer, J. B., and Wrong, N. M.: Fungous Infections of the Skin, Hair, and Nails , Canad. Med. Ass. J. 67:398, 1952. 39. Burke, R. C., and Bumgarner, F. E.: Superficial Mycoses of Veterans , Arch. Derm. Syph. 60:742, 1949.Crossref 40. Stein, C. U.: Beitrag über die Mykosehäufigkeit im Oldenburger Raum und deren Behandlung an der Oldenburger Klinik , Z. Haut Geschlechtskr. 10:57, 1951. 41. Reiss, F.: Steroid Hormones: Their Fungistatic and Genestatic Effect on Pathogenic Fungi , Arch. Derm. Syph. 59:405, 1949.Crossref 42. Wheatley, V. R., and Gillespie, W. H.: Unpublished data. 43. Reed, W. B.; Pidgeon, J., and Becker, S. W.: Patients with Spinal Cord Injury , Arch. Derm. 83:379, 1961.Crossref 44. Sulzberger, M. B.; Lauer, G. C.; Herrmann, F.; Baer, R. L., and Milberg I.: Effects of ACTH and Cortisone on Certain Diseases and Physiologic Functions of the Skin: I. Effects of ACTH , J. Invest. Derm. 16:323, 1951. 45. Grønbaek, P.: Comparative Investigations on the Influence of Cortisone and Prednisone (M.S.D.) on the Content of Sodium and Potassium in Sweat , Acta Rheum. Scand. 2:170, 1956. 46. Lorincz, A. L., in discussion of a paper by Burke, J. Invest. Derm. 36:401, 1961. 47. Bullough, W. S.: Stress and Epidermal Mitotic Activity: I. The Effects of the Adrenal Hormones , J. Endocr. 8:265, 1952.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Tinea Versicolor in Steroid-Treated Patients: Incidence in Patients with Chronic Ulcerative Colitis and Regional Enteritis Treated with Corticotropin and Corticosteroids

Loading next page...
 
/lp/american-medical-association/tinea-versicolor-in-steroid-treated-patients-incidence-in-patients-Rzo8Scx0B4
Publisher
American Medical Association
Copyright
Copyright © 1962 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1962.01590010050007
Publisher site
See Article on Publisher Site

Abstract

Abstract Introduction Since the advent and widespread use of corticosteroids much has been written about the undesirable effects of these drugs. In the past decade the influence of corticosteroids on cutaneous and systemic fungous infections in man and animals has received its share of attention.1-4 However, no systematic research into the possible effects of corticosteroids on tinea versicolor was available, although it was our own clinical impression that there was a higher than expected incidence of this infection in patients with Cushing's syndrome. This observation was confirmed by examining the charts of the 22 patients with Cushing's syndrome hospitalized at The University of Chicago Clinics since 1948. It was found that 3 of these patients had tinea versicolor infections, substantiated by positive KOH preparations. It therefore seemed worthwhile to study the incidence of tinea versicolor in a large number of patients treated with adrenal steroids and corticotropin, as compared with References 1. Burns, R. E.: Fungous Disease as a Complication of Steroid Therapy , A.M.A. Arch. Derm. 77:686, 1958.Crossref 2. Mankowski, Z. T.: Influence of Hormonal Conditions on Experimental Fungus Infection , in Therapy of Fungus Diseases , edited by T. A. Sternberg and V. D. Newcomer, Boston, Little, Brown & Company, 1955. 3. Torack, R. M.: Fungous Infections Associated with Antibiotic and Steroid Therapy , Amer. J. Med. 22:872, 1957.Crossref 4. Mankowski, Z. T., and Littleton, B. J.: Action of Cortisone and ACTH on Experimental Fungus Infections , Antibiot. Chemother. 4:253, 1954. 5. Peck, S. M.; Rosenfeld, H.; Leifer, W., and Bierman, W.: Role of Sweat as a Fungicide , Arch. Derm. Syph. 39:126, 1939.Crossref 6. Rothman, S.; Smiljanic, A. M., and Shapiro, A. L.: Fungistatic Action of Hair Fat on Microsporum Audouini , Proc. Soc. Exp. Biol. Med. 60:394, 1945.Crossref 7. Rothman, S.; Smiljanic, A. M.; Shapiro, A. L., and Weitkamp, A. W.: The Spontaneous Cure of Tinea Capitis in Puberty , J. Invest. Derm. 8:81, 1947.Crossref 8. Lewis, G. M.; Hopper, M. E.; Wilson, J. W., and Plunkett, O. A.: An Introduction to Medical Mycology , Ed. 4, Chicago, Year Book Medical Publishers, Inc., 1958, p. 165. 9. Conant, N. F.; Smith, D. T.; Roger, D. B.; Callaway, J. L., and Martin, D. S.: Manual of Clinical Mycology , Ed. 2, Philadelphia, W. B. Saunders Company, 1954, p. 363. 10. Moore, M.: Cultivation of Malassezia Furfur, Etiological Agent of Pityriasis (Tinea) Versicolor , Mycopathologia 1:53, 1938.Crossref 11. Rothman, S.; Smiljanic, A. M., and Murphy, J. C.: The Nitrogenous Material on Normal Human Skin , J. Invest. Derm. 13:317, 1949.Crossref 12. Rothman, S., and Sullivan, M. B.: Amino Acids on the Normal Human Skin Surface , J. Invest. Derm. 13:319, 1949.Crossref 13. Consden, R.; Gordon, A. H., and Martin, A. J. P.: The Identification of Lower Peptides in Complex Mixtures , Biochem. J. 41:590, 1947. 14. Hardy, T. L.; Holland, D. O., and Nayler, J. H. C.: One-Phase Solvent Mixtures for the Separation of Amino Acids , Analyt. Chem. 27: 971, 1955.Crossref 15. Moore, S., and Stein, W. H.: A Modified Ninhydrin Reagent for the Photometric Determination of Amino Acids and Related Compounds , J. Biol. Chem. 211:907, 1954. 16. Block, R. J.; Durrum, E. L., and Zweig, G.: A Manual of Paper Chromatography and Paper Electrophoresis , Ed. 2, New York, Academic Press, Inc., 1958, p. 99. 17. Stein, W. H., and Moore, S.: Electrolytic Desalting of Amino Acids: Conversion of Arginine to Ornithine , J. Biol. Chem. 190:103, 1951. 18. Clarke, J. T.; Elian, E., and Schwachman, H.: Components of Sweat , Amer. J. Dis. Child. 101:490, 1961.Crossref 19. Leonhardi, G.; Glasenapp, I., and Brühl, G.: Die Freien Aminosaüren der Menschlichen Haut , Hoppe Seyler's Z. Physiol. Chem. 292:89, 1953.Crossref 20. Boughton, B.; Hodgson-Jones, I. S.; MacKenna, R. M. B., and Wormall, A.: Some Observations on the Nature, Origin, and Possible Functions of Squalene and Other Hydrocarbons of Human Sebum , J. Invest. Derm. 24:179, 1955.Crossref 21. Wheatley, V. R.: The Chemistry of Sebum and Some Other Aspects of Skin Chemistry, Ph.D. Thesis, London, St. Bartholomew Medical College, University of London, 1950. 22. Boughton, B., and Wheatley, V. R.: The Fatty Acid Composition of the Skin Surface Fat ('Sebum') of Normal Human Subjects , J. Invest. Derm. 33:49, 1959.Crossref 23. James, A. T., and Martin, A. J. P.: Gas-Liquid Partition Chromatography: The Separation and Micro-Estimation of Volatile Fatty Acids from Formic to Dodecanoic Acid , Biochem. J. 50:679, 1952. 24. James, A. T., and Martin, A. J. P.: Gas-Liquid Chromatography: The Separation and Identification of the Methyl Esters of Saturated and Unsaturated Acids from Formic to n-Octadecanoic Acid , Biochem. J. 63:144, 1956. 25. Keulemans, A. I. M.: Gas Chromatography , edited by C. G. Verver, Ed. 2, New York, Reinhold Publishing Corporation, 1959, p. 33. 26. Kligman, A. M.; Baldridge, G. D., Rebell, G., and Pillsbury, D. M.: The Effect of Cortisone on the Pathologic Responses of Guinea Pigs Infected Cutaneously with Fungi, Viruses, and Bacteria , J. Lab. Clin. Med. 37:615, 1951. 27. Reiss, F., and Caroline, L.: The Influence of ACTH and Cortisone upon Experimental Achorion Quinckeanum Infection and upon Anaphylaxis in Guinea Pigs , J. Invest. Derm. 19:365, 1952.Crossref 28. Sonck, C. E., and Miescher, G.: Der Einfluss von Cortison auf die Meerschweinchentrichophytie , Bull. Schweiz. Akad. Med. Wiss. 8:220, 1952. 29. Jadassohn, W.; Mach, R. S., and Nardin, J.: Effet de la cortisone sur la mycose expérimentale du cobaye , Acta endocr. Kbh. 6:351, 1951. 30. Pillsbury, D. M., and Jacobson, C.: Cushing's Syndrome Complicated by Generalized Trichophyton Rubrum Infection, Society Transactions , A.M.A. Arch. Derm. Syph. 67:436, 1953. 31. Lorincz, A. L., and Reisner, J. E.: Case Report, Program of the Atlantic Dermatologic Conference, Washington, D.C., March 26, 1955. 32. Cremer, G.: The Influence of Adrenocortical Hormones on Dermatomycoses: Especially in the Cushing Syndrome , Dermatologica (Basel) 111: 285, 1955.Crossref 33. Nelson, L. M., and McNiece, K. J.: Recurrent Cushing's Syndrome with Trichophyton Rubrum Infection , A.M.A. Arch. Derm. 80:700, 1959.Crossref 34. Canizares, O.; Shatin, H., and Kellert, A. J.: Cushing's Syndrome and Dermatomycosis , A.M.A. Arch. Derm. 80:705, 1959.Crossref 35. Burke, R. C.: Tinea Versicolor: Susceptibility Factors and Experimental Infection in Human Beings , J. Invest. Derm. 36:389, 1961. 36. Adamson, H. G.: Pityriasis Versicolor with Subsequent Leucodermic Patches , Brit. J. Derm. 61:322, 1949.Crossref 37. Vilanova, X., and Cardenal, C.: in Handbook of Tropical Dermatology and Medical Mycology , edited by R. D. G. Ph. Simons, Amsterdam, Elsevier Press, Inc., 1953, p. 1102. 38. Fischer, J. B., and Wrong, N. M.: Fungous Infections of the Skin, Hair, and Nails , Canad. Med. Ass. J. 67:398, 1952. 39. Burke, R. C., and Bumgarner, F. E.: Superficial Mycoses of Veterans , Arch. Derm. Syph. 60:742, 1949.Crossref 40. Stein, C. U.: Beitrag über die Mykosehäufigkeit im Oldenburger Raum und deren Behandlung an der Oldenburger Klinik , Z. Haut Geschlechtskr. 10:57, 1951. 41. Reiss, F.: Steroid Hormones: Their Fungistatic and Genestatic Effect on Pathogenic Fungi , Arch. Derm. Syph. 59:405, 1949.Crossref 42. Wheatley, V. R., and Gillespie, W. H.: Unpublished data. 43. Reed, W. B.; Pidgeon, J., and Becker, S. W.: Patients with Spinal Cord Injury , Arch. Derm. 83:379, 1961.Crossref 44. Sulzberger, M. B.; Lauer, G. C.; Herrmann, F.; Baer, R. L., and Milberg I.: Effects of ACTH and Cortisone on Certain Diseases and Physiologic Functions of the Skin: I. Effects of ACTH , J. Invest. Derm. 16:323, 1951. 45. Grønbaek, P.: Comparative Investigations on the Influence of Cortisone and Prednisone (M.S.D.) on the Content of Sodium and Potassium in Sweat , Acta Rheum. Scand. 2:170, 1956. 46. Lorincz, A. L., in discussion of a paper by Burke, J. Invest. Derm. 36:401, 1961. 47. Bullough, W. S.: Stress and Epidermal Mitotic Activity: I. The Effects of the Adrenal Hormones , J. Endocr. 8:265, 1952.Crossref

Journal

Archives of DermatologyAmerican Medical Association

Published: Jan 1, 1962

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$499/year

Save searches from
Google Scholar,
PubMed

Create folders to
organize your research

Export folders, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month