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Time Bomb of Lye Ingestion?

Time Bomb of Lye Ingestion? Abstract It is widely recognized that the ingestion of lye is a frequent cause of esophageal stenosis that necessitates lifelong bougie dilation or resection with replacement, commonly by colon. What is less appreciated is the possibility that at the site of stenosis, after a long latency, squamous cell carcinoma may develop. This possibility is the subject of this Marginal Comment. Accidental lye ingestion has perhaps been most commonly reported from Finland, where 10% to 30% lye solutions were widely used for washing purposes. The similarity of these solutions to milk has led to frequent accidental ingestion by children and is occasionally used for suicidal purposes. The development of carcinoma at the site of stricture, although described as early as 1941, has not been frequently commented on. Appleqvist and Salmo estimate that some 70 cases have been reported in the past, but they extract from their 2,414 cases of esophageal cancers 63 References 1. Appleqvist P, Salmo M: Lye corrosion carcinoma of the esophagus . Cancer 45:2655-2658, 1980.Crossref 2. Leape LL, Ashcraft KW, Scarpelli DG, et al: Hazard to health—liquid lye . N Engl J Med 284:578-581, 1971.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

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References (3)

Publisher
American Medical Association
Copyright
Copyright © 1981 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1981.02130250005002
Publisher site
See Article on Publisher Site

Abstract

Abstract It is widely recognized that the ingestion of lye is a frequent cause of esophageal stenosis that necessitates lifelong bougie dilation or resection with replacement, commonly by colon. What is less appreciated is the possibility that at the site of stenosis, after a long latency, squamous cell carcinoma may develop. This possibility is the subject of this Marginal Comment. Accidental lye ingestion has perhaps been most commonly reported from Finland, where 10% to 30% lye solutions were widely used for washing purposes. The similarity of these solutions to milk has led to frequent accidental ingestion by children and is occasionally used for suicidal purposes. The development of carcinoma at the site of stricture, although described as early as 1941, has not been frequently commented on. Appleqvist and Salmo estimate that some 70 cases have been reported in the past, but they extract from their 2,414 cases of esophageal cancers 63 References 1. Appleqvist P, Salmo M: Lye corrosion carcinoma of the esophagus . Cancer 45:2655-2658, 1980.Crossref 2. Leape LL, Ashcraft KW, Scarpelli DG, et al: Hazard to health—liquid lye . N Engl J Med 284:578-581, 1971.Crossref

Journal

American Journal of Diseases of ChildrenAmerican Medical Association

Published: Jan 1, 1981

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