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Thyroglobulin in Benign and Malignant Thyroid Disease

Thyroglobulin in Benign and Malignant Thyroid Disease Thyroglobulin (TG) is a 19S glycoprotein produced by normal thyroids and almost all nonmedullary thyroid cancers. Radioimmunoassays measure serum levels of TG, and these levels are abnormally elevated in patients with metastatic thyroid cancer. Data from our study show that TG measurement is not effective in screening high-risk populations for thyroid cancer. Nevertheless, serum TG determinations are useful for assessing the presence and possibly the extent of residual or recurrent nonmedullary thyroid cancer in patients who have undergone total thyroidectomy. (JAMA 241:923-925, 1979) http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Thyroglobulin in Benign and Malignant Thyroid Disease

JAMA , Volume 241 (9) – Mar 2, 1979

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References (11)

Publisher
American Medical Association
Copyright
Copyright © 1979 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1979.03290350043022
Publisher site
See Article on Publisher Site

Abstract

Thyroglobulin (TG) is a 19S glycoprotein produced by normal thyroids and almost all nonmedullary thyroid cancers. Radioimmunoassays measure serum levels of TG, and these levels are abnormally elevated in patients with metastatic thyroid cancer. Data from our study show that TG measurement is not effective in screening high-risk populations for thyroid cancer. Nevertheless, serum TG determinations are useful for assessing the presence and possibly the extent of residual or recurrent nonmedullary thyroid cancer in patients who have undergone total thyroidectomy. (JAMA 241:923-925, 1979)

Journal

JAMAAmerican Medical Association

Published: Mar 2, 1979

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